(Q33642766)

English

Gram-scale synthesis of (+)-spongistatin 1: development of an improved, scalable synthesis of the F-ring subunit, fragment union, and final elaboration

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Gram-scale synthesis of (+)-spongistatin 1: development of an improved, scalable synthesis of the F-ring subunit, fragment union, and final elaboration (English)

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

author name string

Amos B Smith

1

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Takashi Tomioka

2

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Christina A Risatti

3

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Jeffrey B Sperry

4

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Chris Sfouggatakis

5

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

language of work or name

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publication date

28 August 2008

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Organic Letters

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Europe PubMed Central

PubMed publication ID

28 July 2017

10

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

19

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

4359-4362

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Characterization of apoptosis induced by marine natural products in non small cell lung cancer A549 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819470

21 June 2018

Enantioselective organocatalytic direct aldol reactions of alpha-oxyaldehydes: step one in a two-step synthesis of carbohydrates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819470

21 June 2018

Total synthesis of (+)-spongistatin 1. An effective second-generation construction of an advanced EF Wittig salt, fragment union, and final elaboration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819470

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819470

21 June 2018

A broad-spectrum antifungal from the marine sponge Hyrtios erecta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819470

21 June 2018

Evolution of the Petasis-Ferrier union/rearrangement tactic: construction of architecturally complex natural products possessing the ubiquitous cis-2,6-substituted tetrahydropyran structural element

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819470

30 October 2018

In vitro and in vivo antifungal activities of the marine sponge constituent spongistatin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819470

30 October 2018

Multigram synthesis of the C29-C51 subunit and completion of the total synthesis of altohyrtin C (spongistatin 2).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819470

30 October 2018

Synthesis of a C(29)-C(51) subunit of spongistatin 1 (Altohyrtin A) starting from (R)-3-benzyloxy-2-methylpropan-1-ol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819470

30 October 2018

Total Synthesis of Spongistatin 1: A Synthetic Strategy Exploiting Its Latent Pseudo-Symmetry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819470

30 October 2018

A modular approach to marine macrolide construction. 3. Enantioselective synthesis of the C1-C28 sector of spongistatin 1 (altohyrtin A)

1 reference

https://pubmed.ncbi.nlm.nih.gov/18754594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Spongistatins: Architecturally Complex Natural Products-Part One: A Formal Synthesis of (+)-Spongistatin 1 by Construction of an Advanced ABCD Fragment Financial support was provided by the National Institutes of Health (National Cancer Institut

1 reference

https://pubmed.ncbi.nlm.nih.gov/18754594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spongistatin synthetic studies. An efficient, second-generation construction of an advanced ABCD intermediate

1 reference

https://pubmed.ncbi.nlm.nih.gov/18754594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Asymmetric total synthesis of spongistatins 1 and 2

1 reference

https://pubmed.ncbi.nlm.nih.gov/18754594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diastereoselective synthesis of the C(17)-C(28) fragment (the C-D spiroketal unit) of spongistatin 1 (altohyrtin A) via a kinetically controlled iodo-spiroketalization reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/18754594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis of the C(2)-C(13) fragment (the A-B spiroketal unit) of spongistatin 1 (altohyrtin A): use of a common intermediate for the synthesis of both spongistatin spiroketals

1 reference

https://pubmed.ncbi.nlm.nih.gov/18754594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spongistatin synthetic studies. evolution of a scalable synthesis for the EF fragment of (+)-Spongistatin 1 exploiting a Petasis-Ferrier union/rearrangement tactic

1 reference

https://pubmed.ncbi.nlm.nih.gov/18754594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enantio- and Diastereoselective Allylmetalations: An Easy and Efficient Access to the AB Spiroketal of Spongistatin

1 reference

https://pubmed.ncbi.nlm.nih.gov/18754594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A modular approach to marine macrolide construction. 4. Assembly of C36-C51 and C29-C44 building blocks and evaluation of key coupling reactions targeting spongistatin 1 (altohyrtin A)

1 reference

https://pubmed.ncbi.nlm.nih.gov/18754594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Spongistatins: Architecturally Complex Natural Products-Part Two: Synthesis of the C(29-51) Subunit, Fragment Assembly, and Final Elaboration to (+)-Spongistatin 2

1 reference

https://pubmed.ncbi.nlm.nih.gov/18754594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stereocontrolled Total Synthesis of (+)-Altohyrtin A/Spongistatin 1 Financial support was provided by the EPSRC (GR/L41646), Cambridge Commonwealth Trust (Scholarship to M.J.C.), EC (Marie Curie Postdoctoral Fellowship to J.L.A.), DFG (Postdoctoral

1 reference

https://pubmed.ncbi.nlm.nih.gov/18754594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The spongistatins, potently cytotoxic inhibitors of tubulin polymerization, bind in a distinct region of the vinca domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/18754594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altohyrtins B and C and 5-desacetylaltohyrtin A, potent cytotoxic macrolide congeners of altohyrtin A, from the Okinawan marine sponge Hyrtios altum

1 reference

https://pubmed.ncbi.nlm.nih.gov/18754594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/OL801792K

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

ResearchGate publication ID

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