(Q33643006)

28 July 2017

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title

Engineering viral vectors to subvert the airway defense response (English)

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28 July 2017

Look DC

1

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28 July 2017

Brody SL

series ordinal

2

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28 July 2017

publication date

1 June 1999

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American Journal of Respiratory Cell and Molecular Biology

28 July 2017

published in

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28 July 2017

volume

20

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28 July 2017

issue

6

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28 July 2017

page(s)

1103-1106

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Transfer of genes to humans: early lessons and obstacles to success

28 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1165%2FAJRCMB.20.6.F150

Gene therapy for cystic fibrosis: challenges and future directions

21 January 2018

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Status of gene therapy for cystic fibrosis lung disease

21 January 2018

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Adenovirus-mediated transfer of a recombinant alpha 1-antitrypsin gene to the lung epithelium in vivo

21 January 2018

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Direct gene transfer of human CFTR into human bronchial epithelia of xenografts with E1-deleted adenoviruses.

21 January 2018

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Adenovirus-mediated transfer of the CFTR gene to lung of nonhuman primates: biological efficacy study.

21 January 2018

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Acute responses of non-human primates to airway delivery of an adenovirus vector containing the human cystic fibrosis transmembrane conductance regulator cDNA.

21 January 2018

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Adenovirus-mediated gene transfer transiently corrects the chloride transport defect in nasal epithelia of patients with cystic fibrosis.

21 January 2018

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A controlled study of adenoviral-vector-mediated gene transfer in the nasal epithelium of patients with cystic fibrosis

21 January 2018

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A mouse model for investigating the molecular pathogenesis of adenovirus pneumonia

21 January 2018

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Replication-deficient adenoviral vector for gene transfer potentiates airway neurogenic inflammation.

21 January 2018

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Repeat administration of an adenovirus vector encoding cystic fibrosis transmembrane conductance regulator to the nasal epithelium of patients with cystic fibrosis

21 January 2018

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Pulmonary inflammation induced by incomplete or inactivated adenoviral particles

21 January 2018

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Prolonged transgene expression in cotton rat lung with recombinant adenoviruses defective in E2a.

21 January 2018

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Persistence in muscle of an adenoviral vector that lacks all viral genes

21 January 2018

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Recombinant IL-12 prevents formation of blocking IgA antibodies to recombinant adenovirus and allows repeated gene therapy to mouse lung.

21 January 2018

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Cyclophosphamide diminishes inflammation and prolongs transgene expression following delivery of adenoviral vectors to mouse liver and lung.

21 January 2018

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Oral tolerization to adenoviral antigens permits long-term gene expression using recombinant adenoviral vectors

21 January 2018

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Transient immunomodulation with anti-CD40 ligand antibody and CTLA4Ig enhances persistence and secondary adenovirus-mediated gene transfer into mouse liver

21 January 2018

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Viral strategies of immune evasion

21 January 2018

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"E3/19K" protein of adenovirus type 2 inhibits lysis of cytolytic T lymphocytes by blocking cell-surface expression of histocompatibility class I antigens

21 January 2018

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Safety and efficacy of repetitive adenovirus-mediated transfer of CFTR cDNA to airway epithelia of primates and cotton rats.

21 January 2018

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Stat1 depends on transcriptional synergy with Sp1.

21 January 2018

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Targeted inhibition of interferon-gamma-dependent intercellular adhesion molecule-1 (ICAM-1) expression using dominant-negative Stat1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FAJRCMB.20.6.F150

Two contact regions between Stat1 and CBP/p300 in interferon gamma signaling

21 January 2018

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https://api.crossref.org/works/10.1165%2FAJRCMB.20.6.F150

A novel interferon-inducible domain: structural and functional analysis of the human interferon regulatory factor 1 gene promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FAJRCMB.20.6.F150

STATs and gene regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FAJRCMB.20.6.F150

Direct suppression of Stat1 function during adenoviral infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FAJRCMB.20.6.F150

Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease

21 January 2018

1 reference

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Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FAJRCMB.20.6.F150

Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FAJRCMB.20.6.F150

Does gene therapy call for "STAT" immunity and inflammation at the epithelial barrier?

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FAJRCMB.20.6.F150

Upregulation of class I major histocompatibility complex antigens by interferon gamma is necessary for T-cell-mediated elimination of recombinant adenovirus-infected hepatocytes in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FAJRCMB.20.6.F150

ICAM-1 induction in respiratory cells exposed to a replication-deficient recombinant adenovirus in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FAJRCMB.20.6.F150

Cellular targets for transformation by the adenovirus E1A proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FAJRCMB.20.6.F150

Mechanism of active transcriptional repression by the retinoblastoma protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FAJRCMB.20.6.F150

The 289-amino acid E1A protein of adenovirus binds zinc in a region that is important for trans-activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FAJRCMB.20.6.F150

Ligand-induced assembly and activation of the gamma interferon receptor in intact cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FAJRCMB.20.6.F150

Early-Onset Inflammatory ResponsesIn Vivoto Adenoviral Vectors in the Presence or Absence of Lipopolysaccharide-Induced Inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FAJRCMB.20.6.F150

21 January 2018

Identifiers

DOI

10.1165/AJRCMB.20.6.F150

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28 July 2017

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