(Q33650958)

28 July 2017

title

Beneficial effects of the Rho kinase inhibitor Y27632 in murine puromycin aminonucleoside nephrosis (English)

1 reference

28 July 2017

Liming Wang

1

1 reference

28 July 2017

Mathew J Ellis

2

1 reference

28 July 2017

Timothy A Fields

3

1 reference

28 July 2017

David N Howell

4

1 reference

28 July 2017

Robert F Spurney

5

1 reference

28 July 2017

publication date

27 March 2008

1 reference

Kidney and Blood Pressure Research

28 July 2017

published in

1 reference

28 July 2017

volume

31

1 reference

28 July 2017

issue

2

1 reference

28 July 2017

page(s)

111-121

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The role of podocytes in proteinuria

28 July 2017

cites work

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21 June 2018

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21 June 2018

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Molecular mechanisms and therapeutic strategies of chronic renal injury: renoprotective effect of rho-kinase inhibitor in hypertensive glomerulosclerosis

21 June 2018

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21 June 2018

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Gene Expression Profiles of Podocyte-Associated Molecules as Diagnostic Markers in Acquired Proteinuric Diseases

21 June 2018

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Neph1 and nephrin interaction in the slit diaphragm is an important determinant of glomerular permeability

21 June 2018

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Fyn binds to and phosphorylates the kidney slit diaphragm component Nephrin

21 June 2018

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Homodimerization and heterodimerization of the glomerular podocyte proteins nephrin and NEPH1

21 June 2018

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Nephrin and Neph1 co-localize at the podocyte foot process intercellular junction and form cis hetero-oligomers

21 June 2018

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3-Hydroxy-3-methylglutaryl CoA reductase inhibitors prevent high glucose-induced proliferation of mesangial cells via modulation of Rho GTPase/ p21 signaling pathway: Implications for diabetic nephropathy

21 June 2018

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21 June 2018

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Expression of connective tissue growth factor in human renal fibroblasts: regulatory roles of RhoA and cAMP.

21 June 2018

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Proteinuria and perinatal lethality in mice lacking NEPH1, a novel protein with homology to NEPHRIN

21 June 2018

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Leukotriene D(4)-induced Rho-mediated actin reorganization in human bronchial smooth muscle cells

21 June 2018

1 reference

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Contribution of small GTPase Rho and its target protein rock in a murine model of lung fibrosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2821439

The murine nephrin gene is specifically expressed in kidney, brain and pancreas: inactivation of the gene leads to massive proteinuria and neonatal death

21 June 2018

1 reference

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Kidney angiotensin receptors and their role in renal pathophysiology

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2821439

Nephrin in experimental glomerular disease.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2821439

Cloning of rat nephrin: expression in developing glomeruli and in proteinuric states

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2821439

Pharmacological properties of Y-27632, a specific inhibitor of rho-associated kinases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2821439

Nephrin is specifically located at the slit diaphragm of glomerular podocytes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2821439

Rho and Rho kinase mediate thrombin-stimulated vascular smooth muscle cell DNA synthesis and migration

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2821439

Potential role of platelet activating factor in acute renal failure.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2821439

Positionally cloned gene for a novel glomerular protein--nephrin--is mutated in congenital nephrotic syndrome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2821439

Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2821439

Induction of differentiation in cultured rat and human podocytes.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2821439

Formation of actin stress fibers and focal adhesions enhanced by Rho-kinase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2821439

Rhotekin, a new putative target for Rho bearing homology to a serine/threonine kinase, PKN, and rhophilin in the rho-binding domain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2821439

Dup 753 prevents the development of puromycin aminonucleoside-induced nephrosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2821439

Endothelins in the kidney: physiology and pathophysiology

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2821439

Regulation of blood pressure by the type 1A angiotensin II receptor gene

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2821439

Eicosanoids in experimental and human renal disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2821439

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2821439

Effect of fasudil on Rho-kinase and nephropathy in subtotally nephrectomized spontaneously hypertensive rats

21 June 2018

1 reference

Fluvastatin ameliorates podocyte injury in proteinuric rats via modulation of excessive Rho signaling

21 January 2018

1 reference

Transactivation of the epidermal growth factor receptor by angiotensin II in glomerular podocytes.

21 January 2018

1 reference

Frontal dysfunction and frontal cortical synapse loss in alcoholism--the main cause of alcohol dementia?

21 January 2018

1 reference

Determinants of vascular permeability in the kidney glomerulus.

21 January 2018

1 reference

Nephrin loss in experimental diabetic nephropathy is prevented by deletion of protein kinase C alpha signaling in-vivo.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2821439

Activation of Galpha q-coupled signaling pathways in glomerular podocytes promotes renal injury

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2821439

Gq/G13 signaling by ET-1 in smooth muscle: MYPT1 phosphorylation via ETA and CPI-17 dephosphorylation via ETB.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2821439

Rho-ROCK signal pathway regulates microtubule-based process formation of cultured podocytes--inhibition of ROCK promoted process elongation.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2821439

Pressor responses to platelet-activating factor and thromboxane are mediated by Rho-kinase.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2821439

Cardiovascular effects of Y-27632, a selective Rho-associated kinase inhibitor, assessed in the halothane-anesthetized canine model

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2821439

Rho-kinase inhibition blunts renal vasoconstriction induced by distinct signaling pathways in vivo

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2821439

Fasudil attenuates interstitial fibrosis in rat kidneys with unilateral ureteral obstruction

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2821439

Angiotensin type 2 receptor antagonism confers renal protection in a rat model of progressive renal injury

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2821439

Podocyte-associated molecules in puromycin aminonucleoside nephrosis of the rat.

30 October 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2821439

30 October 2018

Involvement of Rho-kinase pathway for angiotensin II-induced plasminogen activator inhibitor-1 gene expression and cardiovascular remodeling in hypertensive rats

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2821439

Blocking angiotensin II synthesis/activity preserves glomerular nephrin in rats with severe nephrosis.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2821439

Transcriptional Regulation of Nephrin Gene by Peroxisome Proliferator-Activated Receptor- Agonist: Molecular Mechanism of the Antiproteinuric Effect of Pioglitazone

30 October 2018

1 reference

Signaling mechanism of renal fibrosis in unilateral ureteral obstructive kidney disease in ROCK1 knockout mice

21 January 2018

1 reference

12 December 2020

Expression of nephrin in pediatric kidney diseases

1 reference

12 December 2020

Podocytes respond to mechanical stress in vitro

1 reference

12 December 2020

Nephrin dissociates from actin, and its expression is reduced in early experimental membranous nephropathy

1 reference

12 December 2020

Y-27632 prevents tubulointerstitial fibrosis in mouse kidneys with unilateral ureteral obstruction

1 reference

12 December 2020

Nephrin TRAP Mice Lack Slit Diaphragms and Show Fibrotic Glomeruli and Cystic Tubular Lesions

1 reference

12 December 2020

Signaling: focus on Rho in renal disease

1 reference

12 December 2020

Involvement of thromboxane A2, leukotrienes and free radicals in puromycin nephrosis in rats

1 reference

12 December 2020

Simvastatin suppresses glomerular cell proliferation and macrophage infiltration in rats with mesangial proliferative nephritis

1 reference

12 December 2020

Leukotrienes and lipoxins: lipoxygenase-derived modulators of leukocyte recruitment and vascular tone in glomerulonephritis

1 reference

12 December 2020

Preventive effect of Y-27632, a selective Rho-kinase inhibitor, on ischemia/reperfusion-induced acute renal failure in rats

1 reference

12 December 2020

Involvements of Rho-kinase and TGF-beta pathways in aldosterone-induced renal injury

1 reference

12 December 2020

Identifiers

DOI

10.1159/000121531

1 reference

28 July 2017

1 reference

28 July 2017

1 reference