(Q33652525)

28 July 2017

title

Disrupted differentiation and oncogenic transformation of lymphoid progenitors in E2A-HLF transgenic mice (English)

1 reference

28 July 2017

K S Smith

1

1 reference

28 July 2017

J W Rhee

series ordinal

2

1 reference

28 July 2017

L Naumovski

series ordinal

3

1 reference

28 July 2017

M L Cleary

series ordinal

4

1 reference

28 July 2017

language of work or name

English

0 references

publication date

1 June 1999

1 reference

Molecular and Cellular Biology

28 July 2017

published in

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28 July 2017

volume

19

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28 July 2017

issue

6

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28 July 2017

page(s)

4443-4451

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The AD1 and AD2 transactivation domains of E2A are essential for the antiapoptotic activity of the chimeric oncoprotein E2A-HLF

28 July 2017

cites work

1 reference

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21 June 2018

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Regulation of the DBP promoter by PAR proteins and in leukemic cells bearing an E2A/HLF translocation

21 June 2018

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High incidence of T-cell tumors in E2A-null mice and E2A/Id1 double-knockout mice

21 June 2018

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Oncogenic transcription factors in the human acute leukemias

21 June 2018

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Bcl-2 and Bax function independently to regulate cell death

21 June 2018

1 reference

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E2A deficiency leads to abnormalities in alphabeta T-cell development and to rapid development of T-cell lymphomas

21 June 2018

1 reference

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Chimeric oncoprotein E2a-Pbx1 induces apoptosis of hematopoietic cells by a p53-independent mechanism that is suppressed by Bcl-2.

21 June 2018

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Pivotal role for the NFIL3/E4BP4 transcription factor in interleukin 3-mediated survival of pro-B lymphocytes

21 June 2018

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E2A-HLF chimeric transcription factors in pro-B cell acute lymphoblastic leukemia

21 June 2018

1 reference

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Cell transformation mediated by homodimeric E2A-HLF transcription factors

21 June 2018

1 reference

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Bax alpha perturbs T cell development and affects cell cycle entry of T cells

21 June 2018

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Transcriptional regulator of programmed cell death encoded by Caenorhabditis elegans gene ces-2.

21 June 2018

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Reversal of apoptosis by the leukaemia-associated E2A-HLF chimaeric transcription factor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104403

The proto-oncogene HLF and the related basic leucine zipper protein TEF display highly similar DNA-binding and transcriptional regulatory properties

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104403

Chromosomal translocations involving the E2A gene in acute lymphoblastic leukemia: clinical features and molecular pathogenesis

21 June 2018

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Protein dimerization between Lmo2 (Rbtn2) and Tal1 alters thymocyte development and potentiates T cell tumorigenesis in transgenic mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104403

A new transcriptional-activation motif restricted to a class of helix-loop-helix proteins is functionally conserved in both yeast and mammalian cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104403

Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104403

The E2A gene product contains two separable and functionally distinct transcription activation domains

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104403

E2A expression, nuclear localization, and in vivo formation of DNA- and non-DNA-binding species during B-cell development

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104403

DNA-binding specificity and trans-activating potential of the leukemia-associated E2A-hepatic leukemia factor fusion protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104403

Chimaeric oncoproteins resulting from chromosomal translocations in acute lymphoblastic leukaemia.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104403

DNA-binding and transcriptional regulatory properties of hepatic leukemia factor (HLF) and the t(17;19) acute lymphoblastic leukemia chimera E2A-HLF

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104403

Bclx regulates the survival of double-positive thymocytes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104403

E2A-HLF-mediated cell transformation requires both the trans-activation domains of E2A and the leucine zipper dimerization domain of HLF.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104403

Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14;18) translocation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104403

Establishment of a novel heterotransplantable acute lymphoblastic leukemia cell line with a t(17;19) chromosomal translocation the growth of which is inhibited by interleukin-3.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104403

Oncogenic conversion of transcription factors by chromosomal translocations

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104403

CD4 expressed on earliest T-lineage precursor cells in the adult murine thymus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104403

Hlf, a novel hepatic bZIP protein, shows altered DNA-binding properties following fusion to E2A in t(17;19) acute lymphoblastic leukemia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104403

Thymic overexpression of Ttg-1 in transgenic mice results in T-cell acute lymphoblastic leukemia/lymphoma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104403

Fusion of the leucine zipper gene HLF to the E2A gene in human acute B-lineage leukemia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104403

Expression patterns of the hepatic leukemia factor gene in the nervous system of developing and adult mice.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104403

Chimeric homeobox gene E2A-PBX1 induces proliferation, apoptosis, and malignant lymphomas in transgenic mice

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104403

T-cell lineage commitment and cytokine responses of thymic progenitors.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104403

Advantages of detecting monoclonal antibody binding to tissue sections with biotin and avidin reagents in Coplin jars

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104403

Abnormalities of the immune system induced by dysregulated bcl-2 expression in transgenic mice

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104403

T cell tumours of disparate phenotype in mice transgenic for Rbtn-2

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104403

The c-myc oncogene perturbs B lymphocyte development in Eμ-myc transgenic mice

30 October 2018

1 reference

12 December 2020

Thymic dendritic cells and T cells develop simultaneously in the thymus from a common precursor population

1 reference

12 December 2020

Two types of genomic rearrangements create alternative E2A-HLF fusion proteins in t(17;19)-ALL

1 reference

12 December 2020

Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice

1 reference

12 December 2020

Identifiers

DOI

10.1128/MCB.19.6.4443

1 reference

28 July 2017

1 reference

28 July 2017

1 reference