(Q33684164)

28 July 2017

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title

Discovery and development of sesquiterpenoid derived hydroxymethylacylfulvene: a new anticancer drug (English)

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28 July 2017

McMorris TC

1

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28 July 2017

language of work or name

English

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publication date

1 May 1999

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Bioorganic & Medicinal Chemistry

28 July 2017

published in

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28 July 2017

volume

7

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28 July 2017

issue

5

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28 July 2017

page(s)

881-886

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(Hydroxymethyl)acylfulvene: an illudin derivative with superior antitumor properties

28 July 2017

cites work

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Illudin s (lampterol)

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Structure of lampterol (illudin S)

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Metabolites of Clitocybe illudens. IV. Illudalic acid, a sesquiterpenoid, and illudinine, a sesquiterpenoid alkaloid

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7 January 2021

Secondary mould metabolites. Part 31. Isolation and structure elucidation of illudins A and B, and illudalenol, new sesquiterpenoids from Clitocybe illudens

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7 January 2021

Leaianafulvene, a sesquiterpenoid fulvene derivative from cultures of Mycena leaiana

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7 January 2021

On the mechanism of toxicity of illudins: the role of glutathione

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7 January 2021

Metabolism by rat liver cytosol of illudin S, a toxic substance of Lampteromyces japonicus. II. Characterization of illudin S-metabolizing enzyme

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7 January 2021

FUNGAL METABOLITES. THE STRUCTURES OF THE NOVEL SESQUITERPENOIDS ILLUDIN-S AND -M

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7 January 2021

Structure-activity relationships of illudins: analogs with improved therapeutic index

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7 January 2021

Acylfulvenes, a new class of potent antitumor agents

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7 January 2021

Efficacy of HMAF (MGI-114) in the MV522 metastatic lung carcinoma xenograft model nonresponsive to traditional anticancer agents

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7 January 2021

Design and Synthesis of Antitumor Acylfulvenes

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7 January 2021

Metabolism of illudin S, a toxic substance of Lampteromyces japonicus: urinary excretion of mercapturic acids in rat

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7 January 2021

Metabolism of antitumor acylfulvene by rat liver cytosol

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7 January 2021

Preclinical evaluation of illudins as anticancer agents: basis for selective cytotoxicity

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7 January 2021

Efficacy of MGI 114 (6-hydroxymethylacylfulvene, HMAF) against the mdr1/gp170 metastatic MV522 lung carcinoma xenograft

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7 January 2021

Characterization of illudin S sensitivity in DNA repair-deficient Chinese hamster cells. Unusually high sensitivity of ERCC2 and ERCC3 DNA helicase-deficient mutants in comparison to other chemotherapeutic agents

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7 January 2021

Effects on DNA integrity and apoptosis induction by a novel antitumor sesquiterpene drug, 6-hydroxymethylacylfulvene (HMAF, MGI 114)

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7 January 2021

10.1016/S0968-0896(99)00016-4

Identifiers

DOI

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28 July 2017

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