(Q33691497)

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Incremental genetic perturbations to MCM2-7 expression and subcellular distribution reveal exquisite sensitivity of mice to DNA replication stress

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scholarly article

1 reference

Europe PubMed Central

28 July 2017

Incremental genetic perturbations to MCM2-7 expression and subcellular distribution reveal exquisite sensitivity of mice to DNA replication stress (English)

1 reference

Europe PubMed Central

28 July 2017

author name string

Chen-Hua Chuang

1

1 reference

Europe PubMed Central

28 July 2017

Marsha D Wallace

2

1 reference

Europe PubMed Central

28 July 2017

Christian Abratte

3

1 reference

Europe PubMed Central

28 July 2017

Teresa Southard

4

1 reference

Europe PubMed Central

28 July 2017

John C Schimenti

5

1 reference

Europe PubMed Central

28 July 2017

publication date

9 September 2010

1 reference

Europe PubMed Central

28 July 2017

1 reference

Europe PubMed Central

28 July 2017

6

1 reference

Europe PubMed Central

28 July 2017

e1001110

1 reference

Europe PubMed Central

28 July 2017

9

1 reference

Europe PubMed Central

28 July 2017

copyright license

Creative Commons Attribution 4.0 International

9 September 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

DNA damage response and tumorigenesis in Mcm2-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2936539

21 June 2018

Aneuploidy and improved growth are coincident but not causal in a yeast cancer model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2936539

21 June 2018

The Mcm2-7 complex has in vitro helicase activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2936539

21 June 2018

Excess MCM proteins protect human cells from replicative stress by licensing backup origins of replication.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2936539

21 June 2018

Phosphorylation of MCM3 on Ser-112 regulates its incorporation into the MCM2-7 complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2936539

21 June 2018

Sequential expression of pluripotency markers during direct reprogramming of mouse somatic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2936539

21 June 2018

Dormant origins licensed by excess Mcm2-7 are required for human cells to survive replicative stress.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2936539

21 June 2018

Differential requirements for MCM proteins in DNA replication in Drosophila S2 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2936539

21 June 2018

Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2936539

21 June 2018

Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2936539

21 June 2018

Progesterone blocks estrogen-induced DNA synthesis through the inhibition of replication licensing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2936539

21 June 2018

Isolation of the Cdc45/Mcm2-7/GINS (CMG) complex, a candidate for the eukaryotic DNA replication fork helicase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2936539

21 June 2018

Excess Mcm2-7 license dormant origins of replication that can be used under conditions of replicative stress.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2936539

21 June 2018

The MCM complex: its role in DNA replication and implications for cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2936539

21 June 2018

CDK phosphorylation of a novel NLS-NES module distributed between two subunits of the Mcm2-7 complex prevents chromosomal rereplication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2936539

21 June 2018

Preventing re-replication of chromosomal DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2936539

21 June 2018

Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2936539

21 June 2018

DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2936539

21 June 2018

Interaction between human MCM7 and Rad17 proteins is required for replication checkpoint signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2936539

21 June 2018

Analysis and prediction of leucine-rich nuclear export signals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2936539

21 June 2018

Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2936539

21 June 2018

Deregulation of cyclin E in human cells interferes with prereplication complex assembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2936539

21 June 2018

The role of Cdc6 in ensuring complete genome licensing and S phase checkpoint activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2936539

21 June 2018

Eukaryotic MCM proteins: beyond replication initiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2936539

21 June 2018

The structure and function of MCM from archaeal M. Thermoautotrophicum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2936539

21 June 2018

Paradoxes of eukaryotic DNA replication: MCM proteins and the random completion problem.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2936539

21 June 2018

MCM2-7 complexes bind chromatin in a distributed pattern surrounding the origin recognition complex in Xenopus egg extracts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2936539

21 June 2018

Making sense of eukaryotic DNA replication origins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2936539

21 June 2018

DNA replication licensing and human cell proliferation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2936539

21 June 2018

MCM proteins in DNA replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2936539

21 June 2018

Uninterrupted MCM2-7 function required for DNA replication fork progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2936539

21 June 2018

Nuclear localization of Schizosaccharomyces pombe Mcm2/Cdc19p requires MCM complex assembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2936539

21 June 2018

Mcm2 and Mcm3 are constitutive nuclear proteins that exhibit distinct isoforms and bind chromatin during specific cell cycle stages of Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2936539

21 June 2018

In vivo interaction of human MCM heterohexameric complexes with chromatin. Possible involvement of ATP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2936539

21 June 2018

Mouse MCM proteins: complex formation and transportation to the nucleus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2936539

21 June 2018

Physical interactions among Mcm proteins and effects of Mcm dosage on DNA replication in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2936539

21 June 2018

hCDC47, a human member of the MCM family. Dissociation of the nucleus-bound form during S phase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2936539

21 June 2018

DNA polymerase alpha associated protein P1, a murine homolog of yeast MCM3, changes its intranuclear distribution during the DNA synthetic period.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2936539

21 June 2018

A viable allele of Mcm4 causes chromosome instability and mammary adenocarcinomas in mice.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001110

21 January 2018

Reduced Mcm2 expression results in severe stem/progenitor cell deficiency and cancer.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001110

21 January 2018

Genetic screen for chromosome instability in mice: Mcm4 and breast cancer.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001110

21 January 2018

hCDC47, a Human Member of the MCM Family

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001110

21 January 2018

Forward genetic screens for meiotic and mitotic recombination-defective mutants in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2936539

30 October 2018

Reduced dosage of a single fission yeast MCM protein causes genetic instability and S phase delay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2936539

30 October 2018

The nuclear envelope prevents reinitiation of replication by regulating the binding of MCM3 to chromatin in Xenopus egg extracts

1 reference

https://pubmed.ncbi.nlm.nih.gov/20838603

12 December 2020

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10.1371/JOURNAL.PGEN.1001110

1 reference

Europe PubMed Central

28 July 2017

1 reference

Europe PubMed Central

28 July 2017

1 reference

Europe PubMed Central

28 July 2017

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