(Q33691507)

English

ATR-Chk1 pathway inhibition promotes apoptosis after UV treatment in primary human keratinocytes: potential basis for the UV protective effects of caffeine

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

ATR-Chk1 pathway inhibition promotes apoptosis after UV treatment in primary human keratinocytes: potential basis for the UV protective effects of caffeine (English)

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

1 reference

based on heuristic

inferred from title

apoptotic process

1 reference

based on heuristic

inferred from title

author name string

Timothy P Heffernan

1

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Masaoki Kawasumi

2

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Alessandra Blasina

3

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Kenna Anderes

4

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Allan H Conney

5

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Paul Nghiem

6

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

language of work or name

0 references

publication date

26 February 2009

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Journal of Investigative Dermatology

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

129

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

7

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

1805-1815

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Breaching the DNA damage checkpoint via PF-00477736, a novel small-molecule inhibitor of checkpoint kinase 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829385

21 June 2018

Effect of caffeine on the ATR/Chk1 pathway in the epidermis of UVB-irradiated mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829385

21 June 2018

Tea consumption and basal cell and squamous cell skin cancer: results of a case-control study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829385

21 June 2018

Stimulatory effect of oral administration of tea, coffee or caffeine on UVB-induced apoptosis in the epidermis of SKH-1 mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829385

21 June 2018

ATR dependent activation of Chk2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829385

21 June 2018

PPM1D dephosphorylates Chk1 and p53 and abrogates cell cycle checkpoints

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829385

21 June 2018

Inhibition of Chk1 by CEP-3891 accelerates mitotic nuclear fragmentation in response to ionizing Radiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829385

21 June 2018

Ataxia telangiectasia mutated (ATM) and ATM and Rad3-related protein exhibit selective target specificities in response to different forms of DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829385

21 June 2018

Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829385

21 June 2018

Targeting the checkpoint kinases: chemosensitization versus chemoprotection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829385

21 June 2018

Stimulatory effect of topical application of caffeine on UVB-induced apoptosis in mouse skin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829385

21 June 2018

Topical applications of caffeine or (-)-epigallocatechin gallate (EGCG) inhibit carcinogenesis and selectively increase apoptosis in UVB-induced skin tumors in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829385

21 June 2018

Cell cycle checkpoint signaling through the ATM and ATR kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829385

21 June 2018

The radiosensitizing agent 7-hydroxystaurosporine (UCN-01) inhibits the DNA damage checkpoint kinase hChk1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829385

21 June 2018

The 1.7 A crystal structure of human cell cycle checkpoint kinase Chk1: implications for Chk1 regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829385

21 June 2018

Caffeine inhibits the checkpoint kinase ATM

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829385

21 June 2018

UCN-01 suppresses thymidylate synthase gene expression and enhances 5-fluorouracil-induced apoptosis in a sequence-dependent manner.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829385

21 June 2018

Effects of tea, decaffeinated tea, and caffeine on UVB light-induced complete carcinogenesis in SKH-1 mice: demonstration of caffeine as a biologically important constituent of tea.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829385

21 June 2018

Frequent clones of p53-mutated keratinocytes in normal human skin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829385

21 June 2018

UCN-01, 7-hydroxyl-staurosporine, inhibits kinase activity of cyclin-dependent kinases and reduces the phosphorylation of the retinoblastoma susceptibility gene product in A549 human lung cancer cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829385

21 June 2018

Separation of the epidermal sheet by dispase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829385

21 June 2018

Ultraviolet light induction of skin carcinoma in the mouse; influence of cAMP modifying agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829385

21 June 2018

Protection from photodamage by topical application of caffeine after ultraviolet irradiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829385

30 October 2018

Cyclic AMP and cyclic GMP suppress TNFalpha-induced hepatocyte apoptosis by inhibiting FADD up-regulation via a protein kinase A-dependent pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829385

30 October 2018

Administration of green tea or caffeine enhances the disappearance of UVB-induced patches of mutant p53 positive epidermal cells in SKH-1 mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829385

30 October 2018

Differential role of transcription-coupled repair in UVB-induced response of human fibroblasts and keratinocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829385

30 October 2018

Stimulatory effect of topical application of caffeine on UVB-induced apoptosis in the epidermis of p53 and Bax knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829385

30 October 2018

Apoptosis and efficient repair of DNA damage protect human keratinocytes against UVB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829385

30 October 2018

A pilot study of plasma caffeine concentrations in a US sample of smoker and nonsmoker volunteers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829385

30 October 2018

Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829385

30 October 2018

UCN-01: a potent abrogator of G2 checkpoint function in cancer cells with disrupted p53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829385

30 October 2018

A method for the isolation and serial propagation of keratinocytes, endothelial cells, and fibroblasts from a single punch biopsy of human skin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829385

30 October 2018

Coffee drinking, mortality, and cancer incidence: results from a Norwegian prospective study

1 reference

https://pubmed.ncbi.nlm.nih.gov/19242509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of antitumor activity of mitomycin C in vitro and in vivo by UCN-01, a selective inhibitor of protein kinase C

1 reference

https://pubmed.ncbi.nlm.nih.gov/19242509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abrogation of an S-phase checkpoint and potentiation of camptothecin cytotoxicity by 7-hydroxystaurosporine (UCN-01) in human cancer cell lines, possibly influenced by p53 function

1 reference

https://pubmed.ncbi.nlm.nih.gov/19242509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of cisplatin-induced cytotoxicity by 7-hydroxystaurosporine (UCN-01), a new G2-checkpoint inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/19242509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of oral administration of tea, decaffeinated tea, and caffeine on the formation and growth of tumors in high-risk SKH-1 mice previously treated with ultraviolet B light

1 reference

https://pubmed.ncbi.nlm.nih.gov/19242509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenosine 3',5'-phosphate in biological materials. I. Purification and properties of cyclic 3',5'-nucleotide phosphodiesterase and use of this enzyme to characterize adenosine 3',5'-phosphate in human urine

1 reference

https://pubmed.ncbi.nlm.nih.gov/19242509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Protective Role of a Small GTPase RhoE against UVB-induced DNA Damage in Keratinocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19242509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Daily coffee consumption and prevalence of nonmelanoma skin cancer in Caucasian women

1 reference

https://pubmed.ncbi.nlm.nih.gov/19242509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tea intake and squamous cell carcinoma of the skin: influence of type of tea beverages

1 reference

https://pubmed.ncbi.nlm.nih.gov/19242509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ATR inhibition selectively sensitizes G1 checkpoint-deficient cells to lethal premature chromatin condensation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19242509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/JID.2008.435

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Dimensions Publication ID

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

ResearchGate publication ID

0 references

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