(Q33693946)

English

Glucuronidation of 3'-azido-3'-deoxythymidine (zidovudine) by human liver microsomes: relevance to clinical pharmacokinetic interactions with atovaquone, fluconazole, methadone, and valproic acid

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scholarly article

1 reference

Europe PubMed Central

28 July 2017

Glucuronidation of 3'-azido-3'-deoxythymidine (zidovudine) by human liver microsomes: relevance to clinical pharmacokinetic interactions with atovaquone, fluconazole, methadone, and valproic acid (English)

1 reference

Europe PubMed Central

28 July 2017

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

pharmacokinetics

1 reference

based on heuristic

inferred from title

author name string

C B Trapnell

1

1 reference

Europe PubMed Central

28 July 2017

R W Klecker

2

1 reference

Europe PubMed Central

28 July 2017

C Jamis-Dow

3

1 reference

Europe PubMed Central

28 July 2017

J M Collins

4

1 reference

Europe PubMed Central

28 July 2017

language of work or name

0 references

publication date

1 July 1998

1 reference

Europe PubMed Central

28 July 2017

Antimicrobial Agents and Chemotherapy

1 reference

Europe PubMed Central

28 July 2017

42

1 reference

Europe PubMed Central

28 July 2017

7

1 reference

Europe PubMed Central

28 July 2017

1592-1596

1 reference

Europe PubMed Central

28 July 2017

Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105651

28 July 2018

Drug interactions with antiviral drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105651

28 July 2018

Atovaquone inhibits the glucuronidation and increases the plasma concentrations of zidovudine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105651

28 July 2018

Fluconazole. An update of its pharmacodynamic and pharmacokinetic properties and therapeutic use in major superficial and systemic mycoses in immunocompromised patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105651

28 July 2018

Therapy for human immunodeficiency virus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105651

28 July 2018

Utility of in vitro drug metabolism data in predicting in vivo metabolic clearance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105651

28 July 2018

Clinical pharmacokinetics of zidovudine: inter and intraindividual variability and relationship to long term efficacy and toxicity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105651

28 July 2018

Predicting the hepatic clearance of xenobiotics in humans from in vitro data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105651

28 July 2018

Utilization of plasma and urine methadone concentrations to optimize treatment in maintenance clinics: I. Measurement techniques for a clinical setting

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105651

28 July 2018

Guidelines for the use of zidovudine in pregnant women with HIV infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105651

28 July 2018

Drug interactions with zidovudine phosphorylation in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105651

28 July 2018

The use of in vitro metabolism techniques in the planning and interpretation of drug safety studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105651

28 July 2018

Valproic acid. A reappraisal of its pharmacological properties and clinical efficacy in epilepsy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105651

28 July 2018

Specificity of human UDP-glucuronosyltransferases and xenobiotic glucuronidation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105651

28 July 2018

Probenecid and zidovudine metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105651

28 July 2018

The effect of various drugs on the glucuronidation of zidovudine (azidothymidine; AZT) by human liver microsomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105651

28 July 2018

Glucuronidation of 3'-azido-3'-deoxythymidine catalyzed by human liver UDP-glucuronosyltransferase. Significance of nucleoside hydrophobicity and inhibition by xenobiotics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105651

28 July 2018

In vitro inhibition studies of the glucuronidation of 3'-azido-3'-deoxythymidine catalysed by human liver UDP-glucuronosyl transferase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105651

28 July 2018

Glucuronidation of 3'-azido-3'-deoxythymidine in human liver microsomes: enzyme inhibition by drugs and steroid hormones.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105651

28 July 2018

Zidovudine: five years later

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105651

28 July 2018

Increased plasma rifabutin levels with concomitant fluconazole therapy in HIV-infected patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105651

30 October 2018

Effect of fluconazole on zidovudine pharmacokinetics in patients infected with human immunodeficiency virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105651

30 October 2018

Methadone maintenance treatment in opiate dependence: a review.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105651

30 October 2018

Pharmacokinetic interaction between zidovudine and valproic acid in patients infected with human immunodeficiency virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105651

30 October 2018

Metabolism of taxol by human and rat liver in vitro: a screen for drug interactions and interspecies differences.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105651

30 October 2018

Safety, plasma concentrations, and efficacy of high-dose fluconazole in invasive mold infections.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105651

30 October 2018

Atovaquone. A review of its pharmacological properties and therapeutic efficacy in opportunistic infections

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105651

30 October 2018

Glucuronidation of amines and hydroxylated xenobiotics and endobiotics catalyzed by expressed human UGT1.4 protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/9660989

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stereoselective metabolism of fenoldopam and its metabolites in human liver microsomes, cytosol, and slices

1 reference

https://pubmed.ncbi.nlm.nih.gov/9660989

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum levels of methadone in maintenance clients who persist in illicit drug use

1 reference

https://pubmed.ncbi.nlm.nih.gov/9660989

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro glucuronidation of 3'-azido-3'-deoxythymidine by human liver. Role of UDP-glucuronosyltransferase 2 form

1 reference

https://pubmed.ncbi.nlm.nih.gov/9660989

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

3'-azido-3'-deoxythymidine drug interactions. Screening for inhibitors in human liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9660989

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of anticancer drugs on the glucuronidation of 3'-azido-3'-deoxythymidine in human liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9660989

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Utilization of plasma and urine methadone concentration measurements to limit narcotics use in methadone maintenance patients: II. Generation of plasma concentration response curves

1 reference

https://pubmed.ncbi.nlm.nih.gov/9660989

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/AAC.42.7.1592

0 references

1 reference

Europe PubMed Central

28 July 2017

1 reference

Europe PubMed Central

28 July 2017

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