(Q33695083)

28 July 2017

title

Use of genomic data in risk assessment case study: I. Evaluation of the dibutyl phthalate male reproductive development toxicity data set (English)

1 reference

https://api.crossref.org/works/10.1016/J.TAAP.2010.09.006

reverse transcription polymerase chain reaction

15 July 2024

main subject

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20849870

reverse transcription polymerase chain reaction

15 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20849870

no observable adverse effect level

15 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20849870

Organization for Economic Cooperation and Development

15 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20849870

15 July 2024

anogenital distance

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20849870

United States Environmental Protection Agency

15 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20849870

lowest-observed-adverse-effect-level

15 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20849870

15 July 2024

Reference dose

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20849870

15 July 2024

no-observed-effect level

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20849870

no observable adverse effect level

15 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20849870

15 July 2024

Weight of evidence

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20849870

United States Environmental Protection Agency

15 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20849870

Integrated risk information system

15 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20849870

15 July 2024

author name string

Robert Benson

4

1 reference

28 July 2017

Paul Foster

5

1 reference

28 July 2017

Susan L. Makris

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20849870

15 July 2024

Susan Y. Euling

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20849870

15 July 2024

L. Earl Gray

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20849870

15 July 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20849870

15 July 2024

publication date

16 September 2010

1 reference

full work available at URL

28 July 2017

https://api.elsevier.com/content/article/PII:S0041008X10003364?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/J.TAAP.2010.09.006

https://api.elsevier.com/content/article/PII:S0041008X10003364?httpAccept=text/plain

15 July 2024

1 reference

https://api.crossref.org/works/10.1016/J.TAAP.2010.09.006

Toxicology and Applied Pharmacology

15 July 2024

published in

1 reference

28 July 2017

volume

271

1 reference

28 July 2017

issue

3

1 reference

28 July 2017

page(s)

336-348

1 reference

Pathogenesis of male reproductive tract lesions from gestation through adulthood following in utero exposure to Di(n-butyl) phthalate

28 July 2017

cites work

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15 July 2024

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Male reproductive tract lesions at 6, 12, and 18 months of age following in utero exposure to di(n-butyl) phthalate

15 July 2024

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Hypospadias and endocrine disruption: is there a connection?

15 July 2024

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Altered gene expression during rat Wolffian duct development following di(n-butyl) phthalate exposure

15 July 2024

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Critical window of male reproductive tract development in rats following gestational exposure to di-n-butyl phthalate

15 July 2024

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Proposed mode of action for in utero effects of some phthalate esters on the developing male reproductive tract

15 July 2024

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Adverse effects on development of the reproductive system in male offspring of rats given monobutyl phthalate, a metabolite of dibutyl phthalate, during late pregnancy

15 July 2024

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15 July 2024

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Critical period for adverse effects on development of reproductive system in male offspring of rats given di-n-butyl phthalate during late pregnancy

15 July 2024

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15 July 2024

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Use of genomic data in risk assessment case study: II. Evaluation of the dibutyl phthalate toxicogenomic data set.

15 July 2024

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15 July 2024

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Acute and long-term effects of in utero exposure of rats to di(n-butyl) phthalate on testicular germ cell development and proliferation

15 July 2024

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Human 'testicular dysgenesis syndrome': a possible model using in-utero exposure of the rat to dibutyl phthalate

15 July 2024

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Mode of action: impaired fetal leydig cell function--effects on male reproductive development produced by certain phthalate esters

15 July 2024

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Administration of potentially antiandrogenic pesticides (procymidone, linuron, iprodione, chlozolinate, p,p'-DDE, and ketoconazole) and toxic substances (dibutyl- and diethylhexyl phthalate, PCB 169, and ethane dimethane sulphonate) during sexual di

15 July 2024

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Altered Semen Quality in Relation to Urinary Concentrations of Phthalate Monoester and Oxidative Metabolites

15 July 2024

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Effects of dibutyl phthalate in male rabbits following in utero, adolescent, or postpubertal exposure

15 July 2024

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Exposure in utero to di(n-butyl) phthalate alters the vimentin cytoskeleton of fetal rat Sertoli cells and disrupts Sertoli cell-gonocyte contact

15 July 2024

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Molecular and genetic regulation of testis descent and external genitalia development

15 July 2024

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Diverse developmental toxicity of di-n-butyl phthalate in both sexes of rat offspring after maternal exposure during the period from late gestation through lactation

15 July 2024

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Dose-dependent alterations in gene expression and testosterone synthesis in the fetal testes of male rats exposed to di (n-butyl) phthalate

15 July 2024

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Gene expression profiling following in utero exposure to phthalate esters reveals new gene targets in the etiology of testicular dysgenesis

15 July 2024

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Abnormal Leydig Cell aggregation in the fetal testis of rats exposed to di (n-butyl) phthalate and its possible role in testicular dysgenesis

15 July 2024

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Human breast milk contamination with phthalates and alterations of endogenous reproductive hormones in infants three months of age

15 July 2024

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Inter-laboratory control data for reproductive endpoints required in the OPPTS 870.3800/OECD 416 reproduction and fertility test.

15 July 2024

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Expression of insulin-like factor 3 protein in the rat testis during fetal and postnatal development and in relation to cryptorchidism induced by in utero exposure to di (n-Butyl) phthalate

15 July 2024

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Disruption of androgen-regulated male reproductive development by di(n-butyl) phthalate during late gestation in rats is different from flutamide.

15 July 2024

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Dose-dependent alterations in androgen-regulated male reproductive development in rats exposed to Di(n-butyl) phthalate during late gestation

15 July 2024

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Fetal testosterone insufficiency and abnormal proliferation of Leydig cells and gonocytes in rats exposed to di(n-butyl) phthalate

15 July 2024

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Time-dependent and compartment-specific effects of in utero exposure to Di(n-butyl) phthalate on gene/protein expression in the fetal rat testis as revealed by transcription profiling and laser capture microdissection

15 July 2024

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Altered gene profiles in fetal rat testes after in utero exposure to di(n-butyl) phthalate

15 July 2024

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Testicular dysgenesis syndrome: an increasingly common developmental disorder with environmental aspects

15 July 2024

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Testicular effects of di-n-butyl phthalate (DBP): biochemical and histopathological alterations

15 July 2024

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15 July 2024

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15 July 2024

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Di(n-Butyl) Phthalate Impairs Cholesterol Transport and Steroidogenesis in the Fetal Rat Testis through a Rapid and Reversible Mechanism

15 July 2024

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Differential steroidogenic gene expression in the fetal adrenal gland versus the testis and rapid and dynamic response of the fetal testis to di(n-butyl) phthalate

15 July 2024

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Development and descent of the testis in relation to cryptorchidism

15 July 2024

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Identification in rats of a programming window for reproductive tract masculinization, disruption of which leads to hypospadias and cryptorchidism

15 July 2024

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Phthalate ester-induced gubernacular lesions are associated with reduced insl3 gene expression in the fetal rat testis

15 July 2024

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Utilizing toxicogenomic data to understand chemical mechanism of action in risk assessment

15 July 2024

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Reproductive toxicity of di-n-butylphthalate in a continuous breeding protocol in Sprague-Dawley rats

15 July 2024

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Cryptorchidism and testicular cancer: separating fact from fiction

15 July 2024

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Meeting report: moving upstream-evaluating adverse upstream end points for improved risk assessment and decision-making

15 July 2024

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Reproductive and developmental toxicity in F1 Sprague-Dawley male rats exposed to di-n-butyl phthalate in utero and during lactation and determination of its NOAEL.

15 July 2024

64

1 reference

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15 July 2024

Identifiers

1 reference

28 July 2017

1 reference