(Q33695742)

28 July 2017

1 reference

title

Metabotropic G-protein-coupled glutamate receptors as therapeutic targets (English)

1 reference

G protein-coupled receptor

28 July 2017

0 references

author name string

Pellicciari R

series ordinal

1

1 reference

PubMed ID

10419848

28 July 2017

Costantino G

series ordinal

2

1 reference

28 July 2017

1 August 1999

1 reference

Current Opinion in Chemical Biology

28 July 2017

1 reference

28 July 2017

3

1 reference

28 July 2017

4

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28 July 2017

433-440

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Pharmacology and functions of metabotropic glutamate receptors

28 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2899%2980064-7

7 January 2021

Cloning and functional expression of a Drosophila metabotropic glutamate receptor expressed in the embryonic CNS.

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2899%2980064-7

7 January 2021

Glutamatergic activation of hippocampal phospholipase D: postnatal fading and receptor desensitization.

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2899%2980064-7

7 January 2021

Metabotropic glutamate receptor 5 is a disulfide-linked dimer

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2899%2980064-7

7 January 2021

The ligand-binding domain in metabotropic glutamate receptors is related to bacterial periplasmic binding proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2899%2980064-7

7 January 2021

Expression and purification of the extracellular ligand binding region of metabotropic glutamate receptor subtype 1.

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2899%2980064-7

7 January 2021

Mutagenesis and modeling of the GABAB receptor extracellular domain support a venus flytrap mechanism for ligand binding

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2899%2980064-7

7 January 2021

Homology modeling of metabotropic glutamate receptors. (mGluRs) structural motifs affecting binding modes and pharmacological profile of mGluR1 agonists and competitive antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2899%2980064-7

7 January 2021

Metabotropic glutamate receptors: a new target for the therapy of neurodegenerative disorders?

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2899%2980064-7

7 January 2021

Competitive antagonism at metabotropic glutamate receptors by (S)-4-carboxyphenylglycine and (RS)-alpha-methyl-4-carboxyphenylglycine.

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2899%2980064-7

7 January 2021

1-Aminoindan-1,5-dicarboxylic acid: a novel antagonist at phospholipase C-linked metabotropic glutamate receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2899%2980064-7

7 January 2021

(S)-(+)-2-(3'-carboxybicyclo[1.1.1]pentyl)-glycine, a structurally new group I metabotropic glutamate receptor antagonist

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2899%2980064-7

7 January 2021

(RS)-2-chloro-5-hydroxyphenylglycine (CHPG) activates mGlu5, but no mGlu1, receptors expressed in CHO cells and potentiates NMDA responses in the hippocampus

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2899%2980064-7

7 January 2021

Presynaptic mGlu1 type receptors potentiate transmitter output in the rat cortex.

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2899%2980064-7

7 January 2021

Hyperalgesia and allodynia induced by intrathecal (RS)-dihydroxyphenylglycine in rats

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2899%2980064-7

7 January 2021

Synthesis and pharmacological characterization of all sixteen stereoisomers of 2-(2'-carboxy-3'-phenylcyclopropyl)glycine. Focus on (2S,1'S,2'S,3'R)-2-(2'-carboxy-3'-phenylcyclopropyl)glycine, a novel and selective group II metabotropic glutamate re

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2899%2980064-7

7 January 2021

Synthesis and biology of the conformationally restricted ACPD analogue, 2-aminobicyclo[2.1.1]hexane-2,5-dicarboxylic acid-I, a potent mGluR agonist.

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2899%2980064-7

7 January 2021

Design, synthesis, and pharmacological characterization of (+)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (LY354740): a potent, selective, and orally active group 2 metabotropic glutamate receptor agonist possessing anticonvulsant and anxioly

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2899%2980064-7

7 January 2021

https://api.crossref.org/works/10.1016%2FS1367-5931%2899%2980064-7

1 reference

7 January 2021

2-Substituted (2SR)-2-amino-2-((1SR,2SR)-2-carboxycycloprop-1-yl)glycines as potent and selective antagonists of group II metabotropic glutamate receptors. 1. Effects of alkyl, arylalkyl, and diarylalkyl substitution.

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2899%2980064-7

7 January 2021

N-acetylaspartylglutamate inhibits forskolin-stimulated cyclic AMP levels via a metabotropic glutamate receptor in cultured cerebellar granule cells

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2899%2980064-7

7 January 2021

N-acetylaspartylglutamate activates cyclic AMP-coupled metabotropic glutamate receptors in cerebellar astrocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2899%2980064-7

7 January 2021

Type 2 metabotropic glutamate (mGlu) receptors tonically inhibit transmitter release in rat caudate nucleus: in vivo studies with (2S,1'S,2'S,3'R)-2-(2'-carboxy-3'-phenylcyclopropyl)glycine, a new potent and selective antagonist

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2899%2980064-7

7 January 2021

Reversal of phencyclidine effects by a group II metabotropic glutamate receptor agonist in rats

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2899%2980064-7

7 January 2021

Synthesis of the four isomers of 4-aminopyrrolidine-2,4-dicarboxylate: identification of a potent, highly selective, and systemically-active agonist for metabotropic glutamate receptors negatively coupled to adenylate cyclase.

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2899%2980064-7

7 January 2021

Selective activation of group-II metabotropic glutamate receptors is protective against excitotoxic neuronal death.

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2899%2980064-7

7 January 2021

Neuroprotective effects of a systemically active group II metabotropic glutamate receptor agonist LY354740 in a gerbil model of global ischaemia.

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2899%2980064-7

7 January 2021

Effects of the selective metabotropic glutamate agonist LY354740 in a rat model of permanent ischaemia.

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2899%2980064-7

7 January 2021

Neuroprotection by glial metabotropic glutamate receptors is mediated by transforming growth factor-beta

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2899%2980064-7

7 January 2021

The effects of (RS)-alpha-cyclopropyl-4-phosphonophenylglycine ((RS)-CPPG), a potent and selective metabotropic glutamate receptor antagonist

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2899%2980064-7

7 January 2021

(S)-homo-AMPA, a specific agonist at the mGlu6 subtype of metabotropic glutamic acid receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2899%2980064-7

7 January 2021

Group III human metabotropic glutamate receptors 4, 7 and 8: molecular cloning, functional expression, and comparison of pharmacological properties in RGT cells

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2899%2980064-7

7 January 2021

Glutamate activates phospholipase D in hippocampal slices of newborn and adult rats.

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2899%2980064-7

7 January 2021

Pharmacological characterization of metabotropic glutamate receptors coupled to phospholipase D in the rat hippocampus

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2899%2980064-7

7 January 2021

Phospholipase D: enzymology, mechanisms of regulation, and function

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2899%2980064-7

7 January 2021

(2R,1'S,2'R,3'S)-2-(2'-Carboxy-3'-phenylcyclopropyl)glycine (PCCG-13), the first potent and selective competitive antagonist of phospholipase D-coupled metabotropic glutamate receptors: asymmetric synthesis and preliminary biological properties.

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2899%2980064-7

7 January 2021

Altered spatial learning and memory in mice lacking the mGluR4 subtype of metabotropic glutamate receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2899%2980064-7

7 January 2021

10.1016/S1367-5931(99)80064-7

Identifiers

DOI

1 reference

28 July 2017

1 reference

PubMed ID

10419848