(Q33699336)

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Atm-deficient mice exhibit increased sensitivity to dextran sulfate sodium-induced colitis characterized by elevated DNA damage and persistent immune activation

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scholarly article

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Europe PubMed Central

28 July 2017

Atm-deficient mice exhibit increased sensitivity to dextran sulfate sodium-induced colitis characterized by elevated DNA damage and persistent immune activation (English)

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Europe PubMed Central

28 July 2017

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author name string

Aya M Westbrook

1

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Europe PubMed Central

28 July 2017

Robert H Schiestl

2

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Europe PubMed Central

28 July 2017

language of work or name

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publication date

23 February 2010

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Europe PubMed Central

28 July 2017

Cancer Research

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Europe PubMed Central

28 July 2017

70

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Europe PubMed Central

28 July 2017

5

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Europe PubMed Central

28 July 2017

1875-1884

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Europe PubMed Central

28 July 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2831166/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Intestinal mucosal inflammation leads to systemic genotoxicity in mice

1 reference

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Deficiency of the DNA repair enzyme ATM in rheumatoid arthritis

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Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer

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21 June 2018

DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice

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21 June 2018

Increased susceptibility of chronic ulcerative colitis-induced carcinoma development in DNA repair enzyme Ogg1 deficient mice.

1 reference

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21 June 2018

ATM prevents the persistence and propagation of chromosome breaks in lymphocytes

1 reference

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21 June 2018

ATM deficiency impairs thymocyte maturation because of defective resolution of T cell receptor alpha locus coding end breaks

1 reference

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Mechanisms of Disease: pathogenesis of Crohn's disease and ulcerative colitis

1 reference

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21 June 2018

ATM stabilizes DNA double-strand-break complexes during V(D)J recombination.

1 reference

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21 June 2018

Molecular linkage between the kinase ATM and NF-kappaB signaling in response to genotoxic stimuli

1 reference

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21 June 2018

ATM promotes apoptosis and suppresses tumorigenesis in response to Myc.

1 reference

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Constitutive phosphorylation of ATM in lymphoblastoid cell lines from patients with ICF syndrome without downstream kinase activity

1 reference

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21 June 2018

The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor

1 reference

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21 June 2018

Acute colitis induced by dextran sulfate sodium progresses to chronicity in C57BL/6 but not in BALB/c mice: correlation between symptoms and inflammation.

1 reference

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21 June 2018

Immunoglobulin class switch recombination is impaired in Atm-deficient mice

1 reference

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21 June 2018

Nitric oxide-induced cellular stress and p53 activation in chronic inflammation

1 reference

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21 June 2018

ATM deficiency and oxidative stress: a new dimension of defective response to DNA damage

1 reference

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Inflammation and cancer

1 reference

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Chromosomal aberrations: formation, identification and distribution

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Susceptibility of Msh2-deficient mice to inflammation-associated colorectal tumors

1 reference

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Expression of inducible nitric oxide synthase and nitrotyrosine in multiple sclerosis lesions

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A crucial role for CD44 in inflammation

1 reference

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The risk of colorectal cancer in ulcerative colitis: a meta-analysis

1 reference

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21 June 2018

Chronic experimental colitis induced by dextran sulphate sodium (DSS) is characterized by Th1 and Th2 cytokines

1 reference

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The genetic defect in ataxia-telangiectasia

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21 June 2018

Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma

1 reference

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21 June 2018

Atm-deficient mice: a paradigm of ataxia telangiectasia

1 reference

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Lymphocyte life-span and memory

1 reference

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21 June 2018

Dextran sulfate sodium-induced colitis occurs in severe combined immunodeficient mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831166

21 June 2018

Absence of genotoxicity of the carcinogenic sulfated polysaccharides carrageenan and dextran sulfate in mammalian DNA repair and bacterial mutagenicity assays

1 reference

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A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice

1 reference

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21 June 2018

Selective deficiency of CD4+/CD45RA+ lymphocytes in patients with ataxia-telangiectasia.

1 reference

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Atm heterozygosity does not increase tumor susceptibility to ionizing radiation alone or in a p53 heterozygous background.

1 reference

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Fen1 mutations result in autoimmunity, chronic inflammation and cancers

1 reference

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Antioxidant N-acetyl cysteine reduces incidence and multiplicity of lymphoma in Atm deficient mice.

1 reference

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30 October 2018

Atm heterozygosity cooperates with loss of Brca1 to increase the severity of mammary gland cancer and reduce ductal branching

1 reference

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Repeated infection with Opisthorchis viverrini induces accumulation of 8-nitroguanine and 8-oxo-7,8-dihydro-2'-deoxyguanine in the bile duct of hamsters via inducible nitric oxide synthase

1 reference

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Bone marrow transplantation restores immune system function and prevents lymphoma in Atm-deficient mice.

1 reference

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30 October 2018

Optimization of quantitative real-time RT-PCR parameters for the study of lymphoid malignancies

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Skewed T-cell receptor repertoire, decreased thymic output, and predominance of terminally differentiated T cells in ataxia telangiectasia.

1 reference

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Dextran sulfate enhances the level of an oxidative DNA damage biomarker, 8-oxo-7,8-dihydro-2'-deoxyguanosine, in rat colonic mucosa.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831166

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Treatment of dextran sulfate sodium-induced murine colitis by intracolonic cyclosporin

1 reference

https://pubmed.ncbi.nlm.nih.gov/20179206

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The CD69 receptor: a multipurpose cell-surface trigger for hematopoietic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20179206

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based on heuristic

inferred from PubMed ID database lookup

atm and p53 cooperate in apoptosis and suppression of tumorigenesis, but not in resistance to acute radiation toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20179206

12 December 2020

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inferred from PubMed ID database lookup

The comet assay: a method to measure DNA damage in individual cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20179206

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/0008-5472.CAN-09-2584

1 reference

Europe PubMed Central

28 July 2017

1 reference

Europe PubMed Central

28 July 2017

1 reference

Europe PubMed Central

28 July 2017

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