(Q33701768)

28 July 2017

title

SIRT1 ameliorates age-related senescence of mesenchymal stem cells via modulating telomere shelterin (English)

1 reference

28 July 2017

main subject

mesenchymal stem cell

1 reference

Huiqiang Chen

1

1 reference

28 July 2017

Xianbao Liu

2

1 reference

28 July 2017

Wei Zhu

3

1 reference

28 July 2017

Han Chen

4

1 reference

28 July 2017

Xinyang Hu

5

1 reference

28 July 2017

Zhi Jiang

6

1 reference

28 July 2017

Yinchuan Xu

7

1 reference

28 July 2017

Lihan Wang

8

1 reference

28 July 2017

Yu Zhou

9

1 reference

28 July 2017

Panpan Chen

10

1 reference

28 July 2017

Na Zhang

11

1 reference

28 July 2017

Dexing Hu

12

1 reference

28 July 2017

Ling Zhang

13

1 reference

28 July 2017

Yaping Wang

14

1 reference

28 July 2017

Qiyuan Xu

15

1 reference

28 July 2017

Rongrong Wu

16

1 reference

28 July 2017

Hong Yu

17

1 reference

28 July 2017

Jian'an Wang

18

1 reference

28 July 2017

publication date

3 June 2014

1 reference

Frontiers in Aging Neuroscience

28 July 2017

published in

1 reference

28 July 2017

volume

6

1 reference

28 July 2017

page(s)

103

1 reference

SIRT1 in neurodevelopment and brain senescence

28 July 2017

cites work

1 reference

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21 June 2018

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SIRT1 collaborates with ATM and HDAC1 to maintain genomic stability in neurons

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Telomere maintenance genes SIRT1 and XRCC6 impact age-related decline in telomere length but only SIRT1 is associated with human longevity

21 June 2018

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21 June 2018

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Nicotinamide phosphoribosyltransferase (Nampt) affects the lineage fate determination of mesenchymal stem cells: a possible cause for reduced osteogenesis and increased adipogenesis in older individuals

21 June 2018

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21 June 2018

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Sirtuin 1 is upregulated in a subset of hepatocellular carcinomas where it is essential for telomere maintenance and tumor cell growth.

21 June 2018

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Angiogenic properties of aged adipose derived mesenchymal stem cells after hypoxic conditioning.

21 June 2018

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SIRT1 contributes to telomere maintenance and augments global homologous recombination

21 June 2018

1 reference

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21 June 2018

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Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer.

21 June 2018

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Impact of cellular senescence signature on ageing research

21 June 2018

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Impact of Sirt1 on mammalian aging.

21 June 2018

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TIN2-tethered TPP1 recruits human telomerase to telomeres in vivo

21 June 2018

1 reference

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Functional interaction between telomere protein TPP1 and telomerase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042159

SIRT1 promotes proliferation and prevents senescence through targeting LKB1 in primary porcine aortic endothelial cells

21 June 2018

1 reference

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POT1-TPP1 enhances telomerase processivity by slowing primer dissociation and aiding translocation

21 June 2018

1 reference

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Repair of senescent myocardium by mesenchymal stem cells is dependent on the age of donor mice

21 June 2018

1 reference

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Telomere protection by TPP1 is mediated by POT1a and POT1b

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042159

Exercise alters SIRT1, SIRT6, NAD and NAMPT levels in skeletal muscle of aged rats

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042159

A link between the accumulation of DNA damage and loss of multi-potency of human mesenchymal stromal cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042159

Histone H3-K56 acetylation is important for genomic stability in mammals

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042159

A comprehensive review on mesenchymal stem cell growth and senescence.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042159

Serum regulates adipogenesis of mesenchymal stem cells via MEK/ERK-dependent PPARgamma expression and phosphorylation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042159

How shelterin protects mammalian telomeres

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042159

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042159

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042159

Regulation of WRN protein cellular localization and enzymatic activities by SIRT1-mediated deacetylation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042159

SIRT1 acts as a nutrient-sensitive growth suppressor and its loss is associated with increased AMPK and telomerase activity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042159

Telomere stability and telomerase in mesenchymal stem cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042159

Sirt1 modulates premature senescence-like phenotype in human endothelial cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042159

SIRT1 promotes DNA repair activity and deacetylation of Ku70

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042159

The POT1-TPP1 telomere complex is a telomerase processivity factor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042159

TPP1 is a homologue of ciliate TEBP-beta and interacts with POT1 to recruit telomerase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042159

A critical role for TPP1 and TIN2 interaction in high-order telomeric complex assembly

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042159

Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042159

Shelterin: the protein complex that shapes and safeguards human telomeres

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042159

PTOP interacts with POT1 and regulates its localization to telomeres

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042159

Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042159

Bone marrow cells are targets for the anabolic actions of prostaglandin E2 on bone: induction of a transition from nonadherent to adherent osteoblast precursors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042159

Aging alters tissue resident mesenchymal stem cell properties.

21 June 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNAGI.2014.00103

In vitro senescence of rat mesenchymal stem cells is accompanied by downregulation of stemness-related and DNA damage repair genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNAGI.2014.00103

Effects of donor age, gender, and in vitro cellular aging on the phenotypic, functional, and molecular characteristics of mouse bone marrow-derived mesenchymal stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNAGI.2014.00103

Pharmacologically preconditioned skeletal myoblasts are resistant to oxidative stress and promote angiomyogenesis via release of paracrine factors in the infarcted heart

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNAGI.2014.00103

An assessment of the risks of carcinogenicity associated with polyhydroxyalkanoates through an analysis of DNA aneuploid and telomerase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNAGI.2014.00103

Age-associated decrease of SIRT1 expression in rat hippocampus: prevention by late onset caloric restriction.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNAGI.2014.00103

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNAGI.2014.00103

SIRT1 prevents replicative senescence of normal human umbilical cord fibroblast through potentiating the transcription of human telomerase reverse transcriptase gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNAGI.2014.00103

Knockdown of p21(Cip1/Waf1) enhances proliferation, the expression of stemness markers, and osteogenic potential in human mesenchymal stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNAGI.2014.00103

Telomere dysfunction-induced foci arise with the onset of telomeric deletions and complex chromosomal aberrations in resistant chronic lymphocytic leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNAGI.2014.00103

SIRT1 is required for long-term growth of human mesenchymal stem cells.

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24917814

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Expression of the p16INK4A gene is associated closely with senescence of human mesenchymal stem cells and is potentially silenced by DNA methylation during in vitro expansion

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24917814

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3389/FNAGI.2014.00103

1 reference

28 July 2017

1 reference

28 July 2017

1 reference