(Q33709299)

28 July 2017

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title

Melanocortin receptors: perspectives for novel drugs (English)

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28 July 2017

Wikberg JE

1

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28 July 2017

language of work or name

English

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publication date

1 June 1999

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European Journal of Pharmacology

28 July 2017

published in

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28 July 2017

volume

375

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28 July 2017

issue

1-3

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28 July 2017

page(s)

295-310

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Identification of antagonists for melanocortin MC3, MC4 and MC5 receptors

28 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Melanocortins and opiate addiction

7 January 2021

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Cloning and expression of a new member of the melanocyte-stimulating hormone receptor family

7 January 2021

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Agouti antagonism of melanocortin binding and action in the B16F10 murine melanoma cell line

7 January 2021

1 reference

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Characterization of melanocortin receptor subtype expression in murine adipose tissues and in the 3T3-L1 cell line

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Binding of alpha-melanocyte-stimulating hormone to its G-protein-coupled receptor on B-lymphocytes activates the Jak/STAT pathway

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

The neuropeptide alpha-MSH has specific receptors on neutrophils and reduces chemotaxis in vitro

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

The neuropeptide alpha-melanocyte-stimulating hormone inhibits experimental arthritis in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Linkage and association studies between the melanocortin receptors 4 and 5 genes and obesity-related phenotypes in the Québec Family Study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Exocrine gland dysfunction in MC5-R-deficient mice: evidence for coordinated regulation of exocrine gland function by melanocortin peptides

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Alpha-melanocyte-stimulating hormone protects against renal injury after ischemia in mice and rats

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Molecular cloning and expression of the human melanocyte stimulating hormone receptor cDNA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Molecular cloning of a novel human melanocortin receptor

7 January 2021

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Structure-activity studies on the neuroactive and neurotropic effects of neuropeptides related to ACTH.

7 January 2021

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Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y.

7 January 2021

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Production of POMC, CRH-R1, MC1, and MC2 receptor mRNA and expression of tyrosinase gene in relation to hair cycle and dexamethasone treatment in the C57BL/6 mouse skin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Role of melanocortinergic neurons in feeding and the agouti obesity syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

ART (protein product of agouti-related transcript) as an antagonist of MC-3 and MC-4 receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Cloning, expression, and tissue distribution of a fifth melanocortin receptor subtype

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Inhibition by neuropeptides of interleukin-1 beta-induced, prostaglandin-independent hyperalgesia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Evidence for alternate points of attachment for alpha-MSH and its stereoisomer [Nle4, D-Phe7]-alpha-MSH at the melanocortin-1 receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Glutamine235 and arginine272 in human melanocortin 5 receptor determines its low affinity to MSH

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Molecular cloning, expression, and characterization of a fifth melanocortin receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Eating disorders revisited. I: Anorexia nervosa

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Characterization of adrenocorticotropin receptors that appear when 3T3-L1 cells differentiate into adipocytes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Linear and cyclic alpha-melanotropin [4-10]-fragment analogues that exhibit superpotency and residual activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Cyclic lactam alpha-melanotropin analogues of Ac-Nle4-cyclo[Asp5, D-Phe7,Lys10] alpha-melanocyte-stimulating hormone-(4-10)-NH2 with bulky aromatic amino acids at position 7 show high antagonist potency and selectivity at specific melanocortin recep

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Targeted disruption of the melanocortin-4 receptor results in obesity in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Direct effects of corticotrophin on oral keratinocyte cell proliferation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Selective antagonist for the melanocortin 4 receptor (HS014) increases food intake in free-feeding rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Evidence that orexigenic effects of melanocortin 4 receptor antagonist HS014 are mediated by neuropeptide Y.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Evidence for involvement of the melanocortin MC4 receptor in the effects of leptin on food intake and body weight

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Long-term administration of MC4 receptor antagonist HS014 causes hyperphagia and obesity in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Different developmental patterns of melanocortin MC3 and MC4 receptor mRNA: predominance of Mc4 in fetal rat nervous system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

The role of melanocyte-stimulating hormone (MSH) receptor in bovine coat color determination

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Overexpression of an Agouti cDNA in the skin of transgenic mice recapitulates dominant coat color phenotypes of spontaneous mutants

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Molecular cloning of a mouse melanocortin 5 receptor gene widely expressed in peripheral tissues.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Autoradiographic discrimination of melanocortin receptors indicates that the MC3 subtype dominates in the medial rat brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Peptide modulation of inflammatory processes within the brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Agouti protein is an antagonist of the melanocyte-stimulating-hormone receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

The role of alpha-melanocyte-stimulating hormone in cutaneous biology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Binding of anti-inflammatory alpha-melanocyte-stimulating-hormone peptides and proinflammatory cytokines to receptors on melanoma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Direct stimulation of Jak/STAT pathway by the angiotensin II AT1 receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

A missense mutation in the gene for melanocyte-stimulating hormone receptor (MC1R) is associated with the chestnut coat color in horses

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Modulation of ICAM-1 expression by alpha-MSH in human melanoma cells and melanocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Melanocortin-4 receptor mRNA expression in the developing autonomic and central nervous systems

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

The cloning of a family of genes that encode the melanocortin receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Localization of the melanocortin-4 receptor (MC4-R) in neuroendocrine and autonomic control circuits in the brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Infusion of gamma 2-MSH produce a conditioned taste aversion in morphine-dependent rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

α-melanocyte-stimulating hormone reduces interleukin-lβ effects on rat stomach preparations possibly through interference with a type I receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Studies of corticotropin receptors on rat adipocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

ACTH-(1-24) and alpha-MSH antagonize feeding behavior stimulated by kappa opiate agonists

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

A three dimensional model for the interaction of MSH with the melanocortin-1 receptor.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Modeling of the three-dimensional structure of the human melanocortin 1 receptor, using an automated method and docking of a rigid cyclic melanocyte-stimulating hormone core peptide

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

alpha-MSH modulates experimental inflammatory bowel disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

alpha-MSH modulates local and circulating tumor necrosis factor-alpha in experimental brain inflammation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Pigmentation phenotypes of variant extension locus alleles result from point mutations that alter MSH receptor function.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Identification of a receptor for gamma melanotropin and other proopiomelanocortin peptides in the hypothalamus and limbic system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Characterisation of the melanocortin 4 receptor by radioligand binding

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Major pharmacological distinction of the ACTH receptor from other melanocortin receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Evidence indicating that the TM4, EL2, and TM5 of the melanocortin 3 receptor Do not participate in ligand binding

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

The melanocortin 1, 3, 4 or 5 receptors do not have a binding epitope for ACTH beyond the sequence of alpha-MSH.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Selectivity of [Phe-I7], [Ala6], and [D-Ala4,Gln5,Tyr6] substituted ACTH(4-10) analogues for the melanocortin receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Selectivity of cyclic [D-Nal7] and [D-Phe7] substituted MSH analogues for the melanocortin receptor subtypes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Characterisation of D117A and H260A mutations in the melanocortin 1 receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Deletions of the N-terminal regions of the human melanocortin receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Binding of cyclic and linear MSH core peptides to the melanocortin receptor subtypes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Discovery of novel melanocortin4receptor selective MSH analogues

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Evidence indicating that the extracellular loops of the mouse MC5 receptor do not participate in ligand binding

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Melanocortin receptors in leptin effects

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Hypothalamic expression of ART, a novel gene related to agouti, is up-regulated in obese and diabetic mutant mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Structure, regulation and function of NF-kappa B

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Symptomatic relapse in bulimia nervosa following acute tryptophan depletion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Neuropeptide Y chronically injected into the hypothalamus: a powerful neurochemical inducer of hyperphagia and obesity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Evidence of autocrine modulation of macrophage nitric oxide synthase by alpha-melanocyte-stimulating hormone

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Phage display selection on whole cells yields a peptide specific for melanocortin receptor 1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Melanocortin receptor genes in the chicken--tissue distributions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Receptor biology of the melanocortins, a family of neuroimmunomodulatory peptides

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Immunohistochemical detection of the melanocortin 1 receptor in human testis, ovary and placenta using specific monoclonal antibody

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Variants of the melanocyte-stimulating hormone receptor gene are associated with red hair and fair skin in humans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Molecular cloning of a bovine MSH receptor which is highly expressed in the testis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Corticotropin inhibits food intake in rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Selective melanocortin MC4 receptor blockage reduces immobilization stress-induced anorexia in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Melanocortins and cardiovascular regulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Characterisation of ACTH Peptides in Human Skin and Their Activation of the Melanocortin-1 Receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Lipolytic action of corticotropin on rat adipose tissue in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Structure and function of ASP, the human homolog of the mouse agouti gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

A potential mechanism of local anti-inflammatory action of alpha-melanocyte-stimulating hormone within the brain: modulation of tumor necrosis factor-alpha production by human astrocytic cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Localization of ACTH receptor mRNA by in situ hybridization in mouse adrenal gland

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Postnatal expression of melanocortin-3 receptor in rat diencephalon and mesencephalon.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Polyclonal antibodies against human melanocortin MC1 receptor: preliminary immunohistochemical localisation of melanocortin MC1 receptor to malignant melanoma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

Immunological localisation of melanocortin 1 receptor on the cell surface of WM266-4 human melanoma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900298-8

10.1016/S0014-2999(99)00298-8

7 January 2021

Identifiers

DOI

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28 July 2017

1 reference