(Q33711452)

28 July 2017

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title

Host genetic influences on HIV-1 pathogenesis (English)

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28 July 2017

Michael NL

1

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28 July 2017

1 August 1999

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Current Opinion in Immunology

28 July 2017

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28 July 2017

11

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28 July 2017

4

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28 July 2017

466-474

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The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus

28 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

A dual-tropic primary HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

A seven-transmembrane domain receptor involved in fusion and entry of T-cell-tropic human immunodeficiency virus type 1 strains.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

CC CKR5: a RANTES, MIP-1alpha, MIP-1beta receptor as a fusion cofactor for macrophage-tropic HIV-1

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Identification of a major co-receptor for primary isolates of HIV-1

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Association between biological properties of human immunodeficiency virus variants and risk for AIDS and AIDS mortality

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

A new classification for HIV-1

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Change in coreceptor use correlates with disease progression in HIV-1--infected individuals

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

HIV-1 tropism and co-receptor use

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Mapping of independent V3 envelope determinants of human immunodeficiency virus type 1 macrophage tropism and syncytium formation in lymphocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Macrophage tropism of human immunodeficiency virus type 1 and utilization of the CC-CKR5 coreceptor.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Selective expression of the eotaxin receptor CCR3 by human T helper 2 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Functional expression of the eotaxin receptor CCR3 in T lymphocytes co-localizing with eosinophils

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Will multiple coreceptors need to be targeted by inhibitors of human immunodeficiency virus type 1 entry?

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Use of coreceptors other than CCR5 by non-syncytium-inducing adult and pediatric isolates of human immunodeficiency virus type 1 is rare in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Natural infection of a homozygous delta24 CCR5 red-capped mangabey with an R2b-tropic simian immunodeficiency virus.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

A new SIV co-receptor, STRL33.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Expression cloning of new receptors used by simian and human immunodeficiency viruses

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Use of GPR1, GPR15, and STRL33 as coreceptors by diverse human immunodeficiency virus type 1 and simian immunodeficiency virus envelope proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

TYMSTR, a putative chemokine receptor selectively expressed in activated T cells, exhibits HIV-1 coreceptor function.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

STRL33, A novel chemokine receptor-like protein, functions as a fusion cofactor for both macrophage-tropic and T cell line-tropic HIV-1

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Two orphan seven-transmembrane segment receptors which are expressed in CD4-positive cells support simian immunodeficiency virus infection

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

The CC chemokine I-309 inhibits CCR8-dependent infection by diverse HIV-1 strains

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

The cytomegalovirus-encoded chemokine receptor US28 can enhance cell-cell fusion mediated by different viral proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

An orphan seven-transmembrane domain receptor expressed widely in the brain functions as a coreceptor for human immunodeficiency virus type 1 and simian immunodeficiency virus

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

ChemR23, a putative chemoattractant receptor, is expressed in monocyte-derived dendritic cells and macrophages and is a coreceptor for SIV and some primary HIV-1 strains

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Molecular cloning and functional characterization of a novel human CC chemokine receptor (CCR5) for RANTES, MIP-1beta, and MIP-1alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Molecular cloning and functional expression of a new human CC-chemokine receptor gene

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

CCR5 levels and expression pattern correlate with infectability by macrophage-tropic HIV-1, in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8+ T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

The V3 domain of the HIV-1 gp120 envelope glycoprotein is critical for chemokine-mediated blockade of infection

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

HIV-1 entry and macrophage inflammatory protein-1beta-mediated signaling are independent functions of the chemokine receptor CCR5.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Multiple extracellular elements of CCR5 and HIV-1 entry: dissociation from response to chemokines

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Relative resistance to HIV-1 infection of CD4 lymphocytes from persons who remain uninfected despite multiple high-risk sexual exposure

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Genetic Restriction of HIV-1 Infection and Progression to AIDS by a Deletion Allele of the CKR5 Structural Gene

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

The role of a mutant CCR5 allele in HIV-1 transmission and disease progression.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

The role of viral phenotype and CCR-5 gene defects in HIV-1 transmission and disease progression

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Heterozygosity for a deletion in the CKR-5 gene leads to prolonged AIDS-free survival and slower CD4 T-cell decline in a cohort of HIV-seropositive individuals

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Inherited resistance to HIV-1 conferred by an inactivating mutation in CC chemokine receptor 5: studies in populations with contrasting clinical phenotypes, defined racial background, and quantified risk

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

HIV-1 infection in an individual homozygous for the CCR5 deletion allele

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

HIV-1 infection in a man homozygous for CCR5▵32

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

HIV-1 infection in an individual homozygous for CCR5 delta 32. Seroco Study Group

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Homozygous delta 32 deletion of the CCR-5 chemokine receptor gene in an HIV-1-infected patient.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

HIV-1 infection in a heterosexual man homozygous for CCR-5 delta32.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

An HIV-1-infected individual homozygous for the CCR-5 delta32 allele and the SDF-1 3'A allele

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Protection against human immunodeficiency virus type 1 infection in persons with repeated exposure: evidence for T cell immunity in the absence of inherited CCR5 coreceptor defects

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

The impact of the syncytium-inducing phenotype of human immunodeficiency virus on disease progression

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Viral phenotype and CCR5 genotype

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Risk of mother-to-infant transmission of HIV-1 is not reduced in CCR5/delta32ccr5 heterozygotes

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Lack of protection from HIV infection by the mutant HIV coreceptor CCR5 in intravenously HIV infected hemophilia patients

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

CCR5 chemokine receptor variant in HIV-1 mother-to-child transmission and disease progression in children. French Pediatric HIV Infection Study Group

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

CCR5del32 in perinatal HIV-1 infection.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

CCR5 HIV-1 vertical transmission. Women and Infants Transmission Study Group

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Genealogy of the CCR5 locus and chemokine system gene variants associated with altered rates of HIV-1 disease progression

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

CCR5 genotypes in sexually active couples discordant for human immunodeficiency virus type 1 infection status

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Possible influence of the mutant CCR5 Allele on vertical transmission of HIV-1

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Global distribution of the CCR5 gene 32-basepair deletion.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

The deltaccr5 mutation conferring protection against HIV-1 in Caucasian populations has a single and recent origin in Northeastern Europe.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Dating the origin of the CCR5-Delta32 AIDS-resistance allele by the coalescence of haplotypes

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

32 bp CCR-5 gene deletion and resistance to fast progression in HIV-1 infected heterozygotes

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

HIV-Infected Individuals With the CCR5Δ32/CCR5 Genotype Have Lower HIV RNA Levels and Higher CD4 Cell Counts in the Early Years of the Infection Than Do Patients With the Wild Type

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Genetic polymorphism of CCR5 gene and HIV disease: the heterozygous (CCR5/delta ccr5) genotype is neither essential nor sufficient for protection against disease progression. Swiss HIV Cohort.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

A 32-bp deletion within the CCR5 locus protects against transmission of parenterally acquired human immunodeficiency virus but does not affect progression to AIDS-defining illness

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

No evidence for an effect of the CCR5 delta32/+ and CCR2b 64I/+ mutations on human immunodeficiency virus (HIV)-1 disease progression among HIV-1-infected injecting drug users

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Reduced HIV-1 infectability of CD4+ lymphocytes from exposed-uninfected individuals: association with low expression of CCR5 and high production of beta-chemokines

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

The role of CCR5 and CCR2 polymorphisms in HIV-1 transmission and disease progression

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Association between CCR5 genotype and the clinical course of HIV-1 infection

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

MT-2 tropism and CCR-5 genotype strongly influence disease progression in HIV-1-infected individuals

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Impact of heterozygosity for the chemokine receptor CCR5 32-bp-deleted allele on plasma virus load and CD4 T lymphocytes in perinatally human immunodeficiency virus-infected children at 8 years of age.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

HIV-1-resistance phenotype conferred by combination of two separate inherited mutations of CCR5 gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Novel alleles of the chemokine-receptor gene CCR5.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

The extent of genetic variation in the CCR5 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

CXCR4 polymorphisms and HIV-1 pathogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Genomic organization and functional characterization of the chemokine receptor CXCR4, a major entry co-receptor for human immunodeficiency virus type 1

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Contrasting Genetic Influence of CCR2 and CCR5 Variants on HIV-1 Infection and Disease Progression

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

A chemokine receptor CCR2 allele delays HIV-1 disease progression and is associated with a CCR5 promoter mutation.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Distinctive effects of CCR5, CCR2, and SDF1 genetic polymorphisms in AIDS progression.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

CCR2 Polymorphism and HIV Disease

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Chemokine receptor CCR2b 64I polymorphism and its relation to CD4 T-cell counts and disease progression in a Danish cohort of HIV-infected individuals. Copenhagen AIDS cohort.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Genetic effects on HIV disease progression

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Influence of the CCR2-V64I polymorphism on human immunodeficiency virus type 1 coreceptor activity and on chemokine receptor function of CCR2b, CCR3, CCR5, and CXCR4.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

CCR5 promoter polymorphism and HIV-1 disease progression. Multicenter AIDS Cohort Study (MACS).

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Genetic acceleration of AIDS progression by a promoter variant of CCR5.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Functional analysis of the proximal CCR5 promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

The human CC chemokine receptor 5 (CCR5) gene. Multiple transcripts with 5'-end heterogeneity, dual promoter usage, and evidence for polymorphisms within the regulatory regions and noncoding exons

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Genetic restriction of AIDS pathogenesis by an SDF-1 chemokine gene variant. ALIVE Study, Hemophilia Growth and Development Study (HGDS), Multicenter AIDS Cohort Study (MACS), Multicenter Hemophilia Cohort Study (MHCS), San Francisco City Cohort (SF

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Structure and chromosomal localization of the human stromal cell-derived factor 1 (SDF1) gene

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Effect of HIV constructs containing protease-reverse transcriptase fusion proteins on viral replication

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Population biology of antigen presentation by MHC class I molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Natural selection at major histocompatibility complex loci of vertebrates

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Correlates of protective viruses damaging to HIV infection

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Enhanced immunological surveillance in mice heterozygous at the H-2 gene complex

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Association of malaria parasite population structure, HLA, and immunological antagonism.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Association between an MHC class II allele and clearance of hepatitis B virus in the Gambia

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Heterozygote advantage for HLA class-II type in hepatitis B virus infection

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Common west African HLA antigens are associated with protection from severe malaria

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

HLA and HIV-1: heterozygote advantage and B*35-Cw*04 disadvantage

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

Clinical progression of HIV infection: role of NK cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2899%2980078-8

7 January 2021

10.1016/S0952-7915(99)80078-8

Identifiers

DOI

1 reference

28 July 2017

1 reference

PubMed ID

10448150