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Beta-catenin deficiency causes DiGeorge syndrome-like phenotypes through regulation of Tbx1.
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Europe PubMed Central
PMC publication ID
2835329
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20215350%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
title
Beta-catenin deficiency causes DiGeorge syndrome-like phenotypes through regulation of Tbx1
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
2835329
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20215350%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
author
David M. Ornitz
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
2835329
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20215350%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
author name string
Sung-Ho Huh
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1
1 reference
stated in
Europe PubMed Central
PMC publication ID
2835329
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20215350%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
language of work or name
English
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publication date
1 April 2010
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Europe PubMed Central
PMC publication ID
2835329
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20215350%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
number of pages
11
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Development
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Europe PubMed Central
PMC publication ID
2835329
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20215350%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
volume
137
1 reference
stated in
Europe PubMed Central
PMC publication ID
2835329
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20215350%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
issue
7
1 reference
stated in
Europe PubMed Central
PMC publication ID
2835329
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20215350%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
page(s)
1137-1147
1 reference
stated in
Europe PubMed Central
PMC publication ID
2835329
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20215350%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
cites work
Retinoic acid down-regulates Tbx1 expression and induces abnormal differentiation of tongue muscles in fetal mice
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PubMed Central
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21 June 2018
An FGF-WNT gene regulatory network controls lung mesenchyme development
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21 June 2018
The renewal and differentiation of Isl1+ cardiovascular progenitors are controlled by a Wnt/beta-catenin pathway
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835329
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21 June 2018
Formation and differentiation of multiple mesenchymal lineages during lung development is regulated by beta-catenin signaling
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PubMed Central
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21 June 2018
Islet1 cardiovascular progenitors: a single source for heart lineages?
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21 June 2018
Wnt/beta-catenin signaling and cardiogenesis: timing does matter
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21 June 2018
Wnt/beta-catenin signaling promotes expansion of Isl-1-positive cardiac progenitor cells through regulation of FGF signaling
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21 June 2018
Canonical Wnt signaling is a positive regulator of mammalian cardiac progenitors
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PubMed Central
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21 June 2018
Beta-catenin directly regulates Islet1 expression in cardiovascular progenitors and is required for multiple aspects of cardiogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835329
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21 June 2018
Canonical Wnt signaling functions in second heart field to promote right ventricular growth
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PubMed Central
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21 June 2018
Human TBX1 missense mutations cause gain of function resulting in the same phenotype as 22q11.2 deletions
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PubMed Central
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21 June 2018
Wnt/beta-catenin signaling in development and disease
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21 June 2018
DiGeorge syndrome and pharyngeal apparatus development
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PubMed Central
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21 June 2018
Mesodermal expression of Tbx1 is necessary and sufficient for pharyngeal arch and cardiac outflow tract development
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835329
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21 June 2018
Fgf8 is required for anterior heart field development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835329
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21 June 2018
Required, tissue-specific roles for Fgf8 in outflow tract formation and remodeling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835329
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21 June 2018
Dose-dependent interaction of Tbx1 and Crkl and locally aberrant RA signaling in a model of del22q11 syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835329
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21 June 2018
Wnt/beta-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis
1 reference
stated in
PubMed Central
reference URL
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21 June 2018
Inactivation of TGFbeta signaling in neural crest stem cells leads to multiple defects reminiscent of DiGeorge syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835329
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21 June 2018
Sequential roles of Hedgehog and Wnt signaling in osteoblast development
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835329
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21 June 2018
Full spectrum of malformations in velo-cardio-facial syndrome/DiGeorge syndrome mouse models by altering Tbx1 dosage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835329
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21 June 2018
DiGeorge's syndrome: a gene at last
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835329
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21 June 2018
Development of the pharyngeal arches
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835329
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21 June 2018
Tbx1 is regulated by tissue-specific forkhead proteins through a common Sonic hedgehog-responsive enhancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835329
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21 June 2018
Identification of a Wnt/Dvl/beta-Catenin --> Pitx2 pathway mediating cell-type-specific proliferation during development
1 reference
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PubMed Central
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21 June 2018
DiGeorge syndrome: the use of model organisms to dissect complex genetics
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835329
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21 June 2018
Tbx1 mutation causes multiple cardiovascular defects and disrupts neural crest and cranial nerve migratory pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835329
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21 June 2018
Chromosomal microdeletions: dissecting del22q11 syndrome
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PubMed Central
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21 June 2018
Tbx1, a DiGeorge syndrome candidate gene, is regulated by sonic hedgehog during pharyngeal arch development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835329
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21 June 2018
Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835329
retrieved
21 June 2018
Mice lacking the homologue of the human 22q11.2 gene CRKL phenocopy neurocristopathies of DiGeorge syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835329
retrieved
21 June 2018
DiGeorge syndrome phenotype in mice mutant for the T-box gene, Tbx1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835329
retrieved
21 June 2018
Tbx1 haploinsufficieny in the DiGeorge syndrome region causes aortic arch defects in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835329
retrieved
21 June 2018
TBX1 is responsible for cardiovascular defects in velo-cardio-facial/DiGeorge syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835329
retrieved
21 June 2018
The 22q11 deletion syndromes
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835329
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21 June 2018
Fate of the mammalian cardiac neural crest
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835329
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21 June 2018
Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835329
retrieved
21 June 2018
Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835329
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21 June 2018
Generalized lacZ expression with the ROSA26 Cre reporter strain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835329
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21 June 2018
Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835329
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21 June 2018
Expression of the T-box family genes, Tbx1-Tbx5, during early mouse development.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835329
retrieved
21 June 2018
Transcription factor AP-2 is expressed in neural crest cell lineages during mouse embryogenesis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835329
retrieved
21 June 2018
Retinoic acid affects craniofacial patterning by changing Fgf8 expression in the pharyngeal ectoderm
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835329
retrieved
30 October 2018
Haemodynamics determined by a genetic programme govern asymmetric development of the aortic arch.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835329
retrieved
30 October 2018
Mutations in TBX1 genocopy the 22q11.2 deletion and duplication syndromes: a new susceptibility factor for mental retardation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835329
retrieved
30 October 2018
Independent requirements for Hedgehog signaling by both the anterior heart field and neural crest cells for outflow tract development.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835329
retrieved
30 October 2018
FGF8 is required for cell survival at distinct stages of nephrogenesis and for regulation of gene expression in nascent nephrons.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835329
retrieved
30 October 2018
Tbx1 regulates fibroblast growth factors in the anterior heart field through a reinforcing autoregulatory loop involving forkhead transcription factors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835329
retrieved
30 October 2018
Twist regulates cytokine gene expression through a negative feedback loop that represses NF-kappaB activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835329
retrieved
30 October 2018
A genetic link between Tbx1 and fibroblast growth factor signaling.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835329
retrieved
30 October 2018
Identifiers
DOI
10.1242/DEV.045534
1 reference
stated in
Europe PubMed Central
PMC publication ID
2835329
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20215350%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
PMC publication ID
2835329
1 reference
stated in
Europe PubMed Central
PMC publication ID
2835329
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20215350%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
PubMed publication ID
20215350
1 reference
stated in
Europe PubMed Central
PMC publication ID
2835329
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20215350%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
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