(Q33716082)

28 July 2017

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title

H-series protein kinase inhibitors and potential clinical applications (English)

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28 July 2017

N Ono-Saito

1

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28 July 2017

I Niki

series ordinal

2

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28 July 2017

H Hidaka

series ordinal

3

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28 July 2017

publication date

1 May 1999

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Pharmacology & Therapeutics

28 July 2017

published in

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28 July 2017

volume

82

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28 July 2017

issue

2-3

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28 July 2017

page(s)

123-131

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Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase)

28 July 2017

cites work

1 reference

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Vasodilator actions of HA1077 in vitro and in vivo putatively mediated by the inhibition of protein kinase

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7 January 2021

Endothelin: a potential modulator of cerebral vasospasm

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7 January 2021

Blockade of intracellular actions of calcium may protect against ischaemic damage to the gerbil brain

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7 January 2021

Calcium - a life and death signal

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7 January 2021

Switching of the coupling of the beta2-adrenergic receptor to different G proteins by protein kinase A.

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7 January 2021

Modulator protein as a component of the myosin light chain kinase from chicken gizzard

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7 January 2021

Crystal structures of catalytic subunit of cAMP-dependent protein kinase in complex with isoquinolinesulfonyl protein kinase inhibitors H7, H8, and H89. Structural implications for selectivity

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7 January 2021

Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors

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7 January 2021

The protein kinase family: conserved features and deduced phylogeny of the catalytic domains

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7 January 2021

Pharmacology of Protein Kinase Inhibitors

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7 January 2021

Naphthalenesulfonamides as calmodulin antagonists

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7 January 2021

Molecular and cellular pharmacology of a calcium/calmodulin-dependent protein kinase II (CaM kinase II) inhibitor, KN-62, and proposal of CaM kinase phosphorylation cascades

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7 January 2021

Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide-dependent protein kinase and protein kinase C

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7 January 2021

Molecular pharmacology of calcium, calmodulin-dependent myosin phosphorylation in vascular smooth muscle

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7 January 2021

Subcellular redistribution is involved in acute regulation of the brush border Na+/H+ exchanger isoform 3 in human colon adenocarcinoma cell line Caco-2. Protein kinase C-mediated inhibition of the exchanger

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7 January 2021

Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)

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7 January 2021

Regulation of the calmodulin-stimulated protein phosphatase, calcineurin

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7 January 2021

Stat1 combines signals derived from IFN-gamma and LPS receptors during macrophage activation

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7 January 2021

Tyrosine kinase inhibition: an approach to drug development

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7 January 2021

Nitric oxide: a downstream mediator of calcium toxicity in the ischemic cascade

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7 January 2021

Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho

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7 January 2021

Contractile and relaxant effects of phorbol ester in the intestinal smooth muscle of guinea-pig taenia caeci

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7 January 2021

Ca2+ -calmodulin-dependent phosphorylation and platelet secretion

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7 January 2021

Direct evidence for a key role of protein kinase C in the development of vasospasm after subarachnoid hemorrhage

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7 January 2021

Tissue-specific expression of three distinct types of rabbit protein kinase C.

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7 January 2021

Unique inhibitory action of the synthetic compound 2-[N-(2-aminoethyl)-N-(5-isoquinolinesulfonyl)] amino-N-(4-chlorocinnamyl)-N-methylbenzylamine (CKA-1306) against calcium/calmodulin-dependent protein kinase I

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7 January 2021

HA1077, a novel calcium antagonistic antivasospasm drug, increases both cerebral blood flow and glucose metabolism in conscious rats.

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7 January 2021

Inhibition of myosin light chain phosphorylation in cultured smooth muscle cells by HA1077, a new type of vasodilator

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7 January 2021

Disorganization by calcium antagonists of actin microfilament in aortic smooth muscle cells

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7 January 2021

The effects of HA1077 on the cerebral circulation after subarachnoid haemorrhage in dogs

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7 January 2021

Possible prophylactic potential of HA1077, a Ca2+ channel antagonist and vasodilator, on chronic cerebral vasospasm

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7 January 2021

Stimulus-specific patterns of myosin light chain phosphorylation in smooth muscle of rabbit thoracic artery

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7 January 2021

Effects of HA1077, a protein kinase inhibitor, on myosin phosphorylation and tension in smooth muscle

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7 January 2021

Selective inhibition of myosin phosphorylation and tension of hyperplastic arteries by the kinase inhibitor HA1077.

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7 January 2021

The effects of an intracellular calcium antagonist HA 1077 on delayed cerebral vasospasm in dogs

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7 January 2021

Dose escalation trial of a novel calcium antagonist, AT877, in patients with aneurysmal subarachnoid haemorrhage

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7 January 2021

Effect of AT877 on cerebral vasospasm after aneurysmal subarachnoid hemorrhage. Results of a prospective placebo-controlled double-blind trial

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7 January 2021

Effects of HA1077, a novel calciumantagonistic spasmolytic agent on intracerebral arterioles of rats

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7 January 2021

The effects of HA compound calcium antagonists on delayed cerebral vasospasm in dogs

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7 January 2021

Calmodulin Antagonists&rsquo; Binding Sites on Calmodulin

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7 January 2021

The effects of HA1077, a novel protein kinase inhibitor, on reductions of cerebral blood flow and glucose metabolism following acute and/or chronic bilateral carotid artery ligation in Wistar rats.

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7 January 2021

Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension

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7 January 2021

Transforming growth factor-beta1 stimulates protein kinase A in mesangial cells

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7 January 2021

An essential role of myosin light-chain kinase in the regulation of agonist- and fluid flow-stimulated Ca2+ influx in endothelial cells.

1 reference

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7 January 2021

10.1016/S0163-7258(98)00070-9

Identifiers

DOI

1 reference

28 July 2017

1 reference