(Q33716131)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10454202%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

review article

1 reference

title

The transition from a pharmacophore-guided approach to a receptor-guided approach in the design of potent protein kinase C ligands (English)

1 reference

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11 December 2019

0 references

9

1 reference

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11 December 2019

author name string

V E Marquez

1

1 reference

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11 December 2019

K Nacro

2

1 reference

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11 December 2019

S Benzaria

3

1 reference

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11 December 2019

J Lee

4

1 reference

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11 December 2019

R Sharma

5

1 reference

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11 December 2019

K Teng

6

1 reference

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11 December 2019

G W Milne

7

1 reference

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11 December 2019

B Bienfait

8

1 reference

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11 December 2019

N E Lewin

10

1 reference

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11 December 2019

P M Blumberg

11

1 reference

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11 December 2019

publication date

1 May 1999

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10454202%20AND%20SRC:MED&resulttype=core&format=json

Pharmacology & Therapeutics

11 December 2019

published in

1 reference

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11 December 2019

volume

82

1 reference

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11 December 2019

issue

2-3

1 reference

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11 December 2019

page(s)

251-261

1 reference

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Conformationally constrained analogues of diacylglycerol (DAG). 15. The indispensable role of the sn-1 and sn-2 carbonyls in the binding of DAG-lactones to protein kinase C (PK-C)

11 December 2019

cites work

1 reference

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7 January 2021

Inositol trisphosphate and diacylglycerol as second messengers

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7 January 2021

Beta2-chimaerin is a high affinity receptor for the phorbol ester tumor promoters

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7 January 2021

RasGRP, a Ras guanyl nucleotide- releasing protein with calcium- and diacylglycerol-binding motifs

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7 January 2021

Specificity and mechanism of protein kinase C activation by sn-1,2-diacylglycerols

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7 January 2021

Antireplicative and anticytopathic activities of prostratin, a non-tumor-promoting phorbol ester, against human immunodeficiency virus (HIV).

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7 January 2021

Effect of intravenous infusions of 12-O-tetradecanoylphorbol-13-acetate (TPA) in patients with myelocytic leukemia: preliminary studies on therapeutic efficacy and toxicity

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7 January 2021

Diacylglycerols and phosphatidates: which molecular species are intracellular messengers?

1 reference

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7 January 2021

Solution structure of a cysteine rich domain of rat protein kinase C.

1 reference

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7 January 2021

Solution structure of cysteine-rich domain of protein kinase C alpha

1 reference

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7 January 2021

A phase I trial of bryostatin 1 in patients with advanced malignancy using a 24 hour intravenous infusion.

1 reference

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7 January 2021

Cyclohexane diester analogues of phorbol ester as potential activators of protein kinase C.

1 reference

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7 January 2021

The pharmacophore of debromoaplysiatoxin responsible for protein kinase C activation

1 reference

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7 January 2021

Structure/activity relationships of polyfunctional diterpenes of the tigliane type. A pharmacophore model for protein-kinase-C activators based on structure/activity studies and molecular modeling of the tumor promoters 12-O-tetradecanoylphorbol 13-

1 reference

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7 January 2021

Studies on bioactive compounds. 13. Synthesis and lack of growth-inhibitory properties of cyclohexane-1,2,4-triol 1,2-diesters, which resemble ring C of the phorbol ester molecule

1 reference

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7 January 2021

Conformationally constrained analogues of diacylglycerol (DAG)--II. Differential interaction of delta-lactones and gamma-lactones with protein kinase C (PK-C)

1 reference

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7 January 2021

Conformationally constrained analogues of diacylglycerol. 13. Protein kinase C ligands based on templates derived from 2,3-dideoxy-L-erythro(threo)-hexono-1,4-lactone and 2-deoxyapiolactone

1 reference

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7 January 2021

Synthesis of bis-gamma-butyrolactones containing conformationally constrained (S)- and (R)-diacylglycerol structures

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900048-5

7 January 2021

Conformationally Constrained Analogues of Diacylglycerol. 12.1Ultrapotent Protein Kinase C Ligands Based on a Chiral 4,4-Disubstituted Heptono-1,4-lactone Template

1 reference

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7 January 2021

Conformationally constrained analogues of diacylglycerol. 11. Ultrapotent protein kinase C ligands based on a chiral 5-disubstituted tetrahydro-2-furanone template

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900048-5

7 January 2021

Conformationally constrained analogues of diacylglycerol having a perhydrofuro[3,4-c]furan-1,4-dione bis-gamma-butyrolactone skeleton

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900048-5

7 January 2021

Conformationally constrained analogues of diacylglycerol (DAG). 14. Dissection of the roles of the sn-1 and sn-2 carbonyls in DAG mimetics by isopharmacophore replacement

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900048-5

7 January 2021

Distributed automated docking of flexible ligands to proteins: Parallel applications of AutoDock 2.4

1 reference

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7 January 2021

Structural basis of protein kinase C activation by tumor promoters

1 reference

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7 January 2021

Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C

1 reference

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7 January 2021

Phorbol ester binding to protein kinase C requires a cysteine-rich zinc-finger-like sequence

1 reference

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7 January 2021

Display and analysis of patterns of differential activity of drugs against human tumor cell lines: development of mean graph and COMPARE algorithm.

1 reference

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7 January 2021

A phase I study of intravenous bryostatin 1 in patients with advanced cancer

1 reference

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7 January 2021

The stereospecific activation of protein kinase C

1 reference

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7 January 2021

Comparison of the activity of phorbol 12-myristate 13-acetate and the diglyceride glycerol 1-myristate 2-acetate

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900048-5

7 January 2021

Conformationally constrained analogues of diacylglycerol. 10. Ultrapotent protein kinase C ligands based on a racemic 5-disubstituted tetrahydro-2-furanone template

1 reference

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7 January 2021

Phospholipase D in cell signalling and its relationship to phospholipase C.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900048-5

7 January 2021

Protein kinase C. Modeling of the binding site and prediction of binding constants

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900048-5

7 January 2021

Crystal structure of the cys2 activator-binding domain of protein kinase C delta in complex with phorbol ester

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900048-5

7 January 2021

10.1016/S0163-7258(98)00048-5

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10454202%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

1 reference