(Q33717702)

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Niemann-Pick C1 functions independently of Niemann-Pick C2 in the initial stage of retrograde transport of membrane-impermeable lysosomal cargo

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scholarly article

1 reference

Europe PubMed Central

28 July 2017

Niemann-Pick C1 functions independently of Niemann-Pick C2 in the initial stage of retrograde transport of membrane-impermeable lysosomal cargo (English)

1 reference

Europe PubMed Central

28 July 2017

author name string

Stephen D B Goldman

1

1 reference

Europe PubMed Central

28 July 2017

Jeffrey P Krise

2

1 reference

Europe PubMed Central

28 July 2017

language of work or name

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publication date

10 December 2009

1 reference

Europe PubMed Central

28 July 2017

Journal of Biological Chemistry

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Europe PubMed Central

28 July 2017

285

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Europe PubMed Central

28 July 2017

4983-4994

1 reference

Europe PubMed Central

28 July 2017

7

1 reference

Europe PubMed Central

28 July 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2836102/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Deficiency of niemann-pick type C-1 protein impairs release of human immunodeficiency virus type 1 and results in Gag accumulation in late endosomal/lysosomal compartments

1 reference

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21 June 2018

A fluorescence resonance energy transfer-based approach for investigating late endosome-lysosome retrograde fusion events

1 reference

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21 June 2018

Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium

1 reference

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21 June 2018

NPC1/NPC2 function as a tag team duo to mobilize cholesterol

1 reference

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21 June 2018

NPC2 facilitates bidirectional transfer of cholesterol between NPC1 and lipid bilayers, a step in cholesterol egress from lysosomes

1 reference

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21 June 2018

Niemann-Pick C1 functions in regulating lysosomal amine content

1 reference

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Repair of injured plasma membrane by rapid Ca2+-dependent endocytosis

1 reference

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21 June 2018

The concept of "aldehyde load" in neurodegenerative mechanisms: cytotoxicity of the polyamine degradation products hydrogen peroxide, acrolein, 3-aminopropanal, 3-acetamidopropanal and 4-aminobutanal in a retinal ganglion cell line

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Neurotoxicity of reactive aldehydes: the concept of "aldehyde load" as demonstrated by neuroprotection with hydroxylamines

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21 June 2018

Cholesterol accumulation sequesters Rab9 and disrupts late endosome function in NPC1-deficient cells

1 reference

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21 June 2018

Niemann-Pick C1 protein facilitates the efflux of the anticancer drug daunorubicin from cells according to a novel vesicle-mediated pathway

1 reference

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21 June 2018

Membrane traffic to and from lysosomes

2 references

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Intracellular trafficking of Niemann-Pick C proteins 1 and 2: obligate components of subcellular lipid transport

1 reference

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21 June 2018

Genetic evidence for nonredundant functional cooperativity between NPC1 and NPC2 in lipid transport

1 reference

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21 June 2018

Massive cell vacuolization induced by organic amines such as procainamide.

1 reference

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21 June 2018

Niemann-Pick disease type C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836102

21 June 2018

Telomerase immortalization upregulates Rab9 expression and restores LDL cholesterol egress from Niemann-Pick C1 late endosomes

1 reference

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21 June 2018

Rab proteins mediate Golgi transport of caveola-internalized glycosphingolipids and correct lipid trafficking in Niemann-Pick C cells

1 reference

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21 June 2018

Repairing a torn cell surface: make way, lysosomes to the rescue.

1 reference

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21 June 2018

Visualization of Rab9-mediated vesicle transport from endosomes to the trans-Golgi in living cells

1 reference

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21 June 2018

Cessation of rapid late endosomal tubulovesicular trafficking in Niemann-Pick type C1 disease

1 reference

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21 June 2018

Dynamic movements of organelles containing Niemann-Pick C1 protein: NPC1 involvement in late endocytic events

1 reference

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21 June 2018

Neurons in Niemann-Pick disease type C accumulate gangliosides as well as unesterified cholesterol and undergo dendritic and axonal alterations

1 reference

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21 June 2018

Identification of HE1 as the second gene of Niemann-Pick C disease

1 reference

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21 June 2018

Niemann-pick type C1 (NPC1) overexpression alters cellular cholesterol homeostasis

1 reference

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21 June 2018

Lysosome-endosome fusion and lysosome biogenesis.

1 reference

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21 June 2018

The Niemann-Pick C1 protein resides in a vesicular compartment linked to retrograde transport of multiple lysosomal cargo

1 reference

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21 June 2018

Abnormal transport along the lysosomal pathway in mucolipidosis, type IV disease

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21 June 2018

Fusion of lysosomes with late endosomes produces a hybrid organelle of intermediate density and is NSF dependent

1 reference

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21 June 2018

Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis

1 reference

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21 June 2018

Lysosomes behave as Ca2+-regulated exocytic vesicles in fibroblasts and epithelial cells

1 reference

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21 June 2018

Evidence for retrograde traffic between terminal lysosomes and the prelysosomal/late endosome compartment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836102

21 June 2018

Commentary. Lysosomotropic agents

1 reference

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Ganglioside storage, hexosaminidase lability, and urinary oligosaccharides in adult Sandhoff's disease

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21 June 2018

The intracellular transport of low density lipoprotein-derived cholesterol is defective in Niemann-Pick type C fibroblasts

1 reference

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Immunocytochemical characterization of the endocytic and phagolysosomal compartments in peritoneal macrophages

1 reference

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Replacement of endogenous cholesteryl esters of low density lipoprotein with exogenous cholesteryl linoleate. Reconstitution of a biologically active lipoprotein particle

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21 June 2018

The sterol-sensing domain of the Niemann-Pick C1 (NPC1) protein regulates trafficking of low density lipoprotein cholesterol

1 reference

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Cellular and lysosomal uptake of methylamine in isolated rat hepatocytes

1 reference

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The role of intraorganellar Ca(2+) in late endosome-lysosome heterotypic fusion and in the reformation of lysosomes from hybrid organelles

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Regional and temporal alterations of ODC/polyamine system during ALS-like neurodegenerative motor syndrome in G93A transgenic mice

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Structural and physical changes in lysosomes from isolated rat hepatocytes treated with methylamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/20007703

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Group C Niemann-Pick disease: faulty regulation of low-density lipoprotein uptake and cholesterol storage in cultured fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/20007703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain polyamine levels are altered in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20007703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dense core lysosomes can fuse with late endosomes and are re-formed from the resultant hybrid organelles

1 reference

https://pubmed.ncbi.nlm.nih.gov/20007703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

THE QUANTITATIVE DETERMINATION OF GANGLIOSIDES AND THEIR NEURAMINIC ACID-FREE DERIVATIVES IN INFANTILE, JUVENILE AND FORMS OF AMAUROTIC IDIOCY AND AN UNUSUAL LATE INFANTILE BIOCHEMICAL FORM

1 reference

https://pubmed.ncbi.nlm.nih.gov/20007703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M109.037622

1 reference

Europe PubMed Central

28 July 2017

1 reference

Europe PubMed Central

28 July 2017

1 reference

Europe PubMed Central

28 July 2017

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