(Q33723609)

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The pathogenesis of acute promyelocytic leukaemia: evaluation of the role of molecular diagnosis and monitoring in the management of the disease

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Europe PubMed Central

PubMed publication ID

28 July 2017

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Europe PubMed Central

The pathogenesis of acute promyelocytic leukaemia: evaluation of the role of molecular diagnosis and monitoring in the management of the disease (English)

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Europe PubMed Central

PubMed publication ID

28 July 2017

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Grimwade D

1

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Europe PubMed Central

PubMed publication ID

28 July 2017

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publication date

1 September 1999

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Europe PubMed Central

PubMed publication ID

28 July 2017

British Journal of Haematology

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Europe PubMed Central

PubMed publication ID

28 July 2017

106

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Europe PubMed Central

PubMed publication ID

28 July 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

591-613

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

The promyelocytic leukemia gene product (PML) forms stable complexes with the retinoblastoma protein

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Antisense oligonucleotides from the stage-specific myeloid zinc finger gene MZF-1 inhibit granulopoiesis in vitro

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

In vivo and in vitro characterization of the B1 and B2 zinc-binding domains from the acute promyelocytic leukemia protooncoprotein PML

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

The translocation t(8;16)(p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREB-binding protein

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-alpha

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Regulation of activity of the transcription factor GATA-1 by acetylation

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Outcome prediction in childhood acute lymphoblastic leukaemia by molecular quantification of residual disease at the end of induction

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Developmental biology. Reading the retinoid signals.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

A PMLRARalpha transgene initiates murine acute promyelocytic leukemia

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Randomised comparison of addition of autologous bone-marrow transplantation to intensive chemotherapy for acute myeloid leukaemia in first remission: results of MRC AML 10 trial. UK Medical Research Council Adult and Children's Leukaemia Working Par

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Demonstration of a RNA-dependent nuclear interaction between the promyelocytic leukaemia protein and glyceraldehyde-3-phosphate dehydrogenase

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia. European Organization for Research and Treatment of Cancer--Childhood Leukemia Cooperative Group

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Role of CBP/P300 in nuclear receptor signalling

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

NuMA: a protein involved in nuclear structure, spindle assembly, and nuclear re-formation

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor alpha gene to a novel transcribed locus

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

The PML-RARα fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Aberrant recruitment of the nuclear receptor corepressor-histone deacetylase complex by the acute myeloid leukemia fusion partner ETO.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Minimal residual disease analysis for the prediction of relapse in children with standard-risk acute lymphoblastic leukaemia.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Acute leukemia with promyelocytic features in PML/RARalpha transgenic mice

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Distinct interactions of PML-RARalpha and PLZF-RARalpha with co-repressors determine differential responses to RA in APL.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Structure, organization, and dynamics of promyelocytic leukemia protein nuclear bodies.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Deregulation of NPM and PLZF in a variant t(5;17) case of acute promyelocytic leukemia.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Identification of three major sentrinization sites in PML

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Genetic analysis of RXR alpha developmental function: convergence of RXR and RAR signaling pathways in heart and eye morphogenesis.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Leukemia-associated retinoic acid receptor alpha fusion partners, PML and PLZF, heterodimerize and colocalize to nuclear bodies

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Localization of nascent RNA and CREB binding protein with the PML-containing nuclear body.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Sequence-specific DNA binding and transcriptional regulation by the promyelocytic leukemia zinc finger protein.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Role of the histone deacetylase complex in acute promyelocytic leukaemia

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

PML suppresses oncogenic transformation of NIH/3T3 cells by activated neu.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Transcriptional activation of the human p21(WAF1/CIP1) gene by retinoic acid receptor. Correlation with retinoid induction of U937 cell differentiation

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

ETO, a target of t(8;21) in acute leukemia, interacts with the N-CoR and mSin3 corepressors

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

A novel, erythroid cell-specific murine transcription factor that binds to the CACCC element and is related to the Krüppel family of nuclear proteins

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

PML, a growth suppressor disrupted in acute promyelocytic leukemia

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Conjugation with the ubiquitin-related modifier SUMO-1 regulates the partitioning of PML within the nucleus

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Ikaros in hemopoietic lineage determination and homeostasis

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Defective haematopoiesis in fetal liver resulting from inactivation of the EKLF gene

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Retinoic acid enhances the expression of interferon-induced proteins: evidence for multiple mechanisms of action

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Lethal beta-thalassaemia in mice lacking the erythroid CACCC-transcription factor EKLF

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

PML induces a novel caspase-independent death process

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Crystal structure of the RAR-gamma ligand-binding domain bound to all-trans retinoic acid

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

The acute promyelocytic leukaemia specific PML and PLZF proteins localize to adjacent and functionally distinct nuclear bodies

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Prolonged molecular remission after PML/RAR alpha-positive autologous peripheral blood stem cell transplantation in acute promyelocytic leukemia: is relevant pretransplant minimal residual disease in the graft?

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Does this have a familiar RING?

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Leukemia and the disruption of normal hematopoiesis

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Interaction of SP100 with HP1 proteins: a link between the promyelocytic leukemia-associated nuclear bodies and the chromatin compartment

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

The promyelocytic leukemia zinc finger protein affects myeloid cell growth, differentiation, and apoptosis

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

The RAR alpha-PLZF chimera associated with Acute Promyelocytic Leukemia has retained a sequence-specific DNA-binding domain.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Ataxin-1 with an expanded glutamine tract alters nuclear matrix-associated structures

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Complete remission after treatment of acute promyelocytic leukemia with arsenic trioxide

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Steroid receptor coactivator-1 is a histone acetyltransferase

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Developmentally regulated expression of a human "finger"-containing gene encoded by the 5' half of the ret transforming gene

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Stimulation of calf thymus DNA polymerase alpha activity by nucleolar protein B23

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

All-trans-retinoic acid in acute promyelocytic leukemia

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

The promyelocytic leukemia protein interacts with Sp1 and inhibits its transactivation of the epidermal growth factor receptor promoter

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Prognostic value of minimal residual disease in acute lymphoblastic leukaemia in childhood.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Therapeutic targeting of transcription in acute promyelocytic leukemia by use of an inhibitor of histone deacetylase.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

ETO, fusion partner in t(8;21) acute myeloid leukemia, represses transcription by interaction with the human N-CoR/mSin3/HDAC1 complex

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Role of PML in cell growth and the retinoic acid pathway

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Retinoic acid regulates aberrant nuclear localization of PML-RAR alpha in acute promyelocytic leukemia cells

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Fusion of retinoic acid receptor alpha to NuMA, the nuclear mitotic apparatus protein, by a variant translocation in acute promyelocytic leukaemia

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Leukemia translocation protein PLZF inhibits cell growth and expression of cyclin A.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Acetylation and modulation of erythroid Krüppel-like factor (EKLF) activity by interaction with histone acetyltransferases

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Proto-oncogene PML controls genes devoted to MHC class I antigen presentation

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Arsenic-induced PML targeting onto nuclear bodies: implications for the treatment of acute promyelocytic leukemia

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Molecular detection of t(8;21)/AML1-ETO in AML M1/M2: correlation with cytogenetics, morphology and immunophenotype

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Identification of major nucleolar proteins as candidate mitotic substrates of cdc2 kinase

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Quantification of PML-RARalpha transcripts in acute promyelocytic leukaemia: explanation for the lack of sensitivity of RT-PCR for the detection of minimal residual disease and induction of the leukaemia-specific mRNA by alpha interferon

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Inhibition of skin development by targeted expression of a dominant-negative retinoic acid receptor

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

A case of cryptic acute promyelocytic leukemia

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Preliminary experience in external quality control of RT-PCR PML-RAR alpha detection in promyelocytic leukemia

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Immunological detection of minimal residual disease in children with acute lymphoblastic leukaemia

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Acute promyelocytic leukaemia with t(11;17)(q23;q12-21) and a good initial response to prolonged ATRA and combination chemotherapy

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

PML/RAR alpha APL with undifferentiated morphology and stem cell immunophenotype

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Salvage of patients with acute promyelocytic leukaemia with residual disease following ABMT performed in second CR using all-trans retinoic acid

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Characterisation of the PML/RAR alpha rearrangement associated with t(15;17) acute promyelocytic leukaemia.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

What happens subsequently in AML when cytogenetic abnormalities persist at bone marrow harvest? Results of the 10th UK MRC AML trial. Medical Research Council Leukaemia Working Parties

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Immunophenotype of adult and childhood acute promyelocytic leukaemia: correlation with morphology, type of PML gene breakpoint and clinical outcome. A cooperative Italian study on 196 cases

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Frequency of CBF beta/MYH11 fusion transcripts in patients entered into the U.K. MRC AML trials. The MRC Adult Leukaemia Working Party

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Incidence of AML1/ETO fusion transcripts in patients entered into the MRC AML trials. MRC Adult Leukaemia Working Party

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Evidence for a 15; 17 translocation in every patient with acute promyelocytic leukemia

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Molecular evaluation of residual disease as a predictor of relapse in acute promyelocytic leukaemia

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Differentiation of t(5;17) variant acute promyelocytic leukemic blasts by all-trans retinoic acid

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

15/17 translocation, a consistent chromosomal change in acute promyelocytic leukaemia

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

RT-PCR method with increased sensitivity shows persistence of PML-RARA fusion transcripts in patients in long-term remission of APL

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Differential SMN2 expression associated with SMA severity

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1999.01501.X

21 January 2018

Identifiers

10.1046/J.1365-2141.1999.01501.X

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

ResearchGate publication ID

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