(Q33730450)

29 July 2017

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title

Sodium-hydrogen exchange and platelet function (English)

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29 July 2017

Rosskopf D

1

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29 July 2017

publication date

1 July 1999

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Journal of Thrombosis and Thrombolysis

29 July 2017

published in

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29 July 2017

volume

8

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29 July 2017

issue

1

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29 July 2017

page(s)

15-24

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Sodium-proton exchange and primary hypertension. An update

29 July 2017

cites work

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12 December 2020

Variations in the apparent pH set point for activation of platelet Na-H antiport

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12 December 2020

Na+/H+ exchange and aggregation of human platelets activated by ADP: the exchange is not required for aggregation

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12 December 2020

Stimulation of human platelets by collagen occurs by a Na+/H+ exchanger independent mechanism

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12 December 2020

Rapid determination of the elevated Na(+)-H+ exchange in platelets of patients with essential hypertension using an optical swelling assay

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12 December 2020

The Na+/H+exchanger role in the intracellular pH regulation of human platelets

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12 December 2020

Elevation of pHi is not an essential step in calcium mobilisation in fura-2-loaded human platelets

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12 December 2020

Molecular cloning, genomic organization, and functional expression of Na+/H+ exchanger isoform 5 (NHE5) from human brain

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12 December 2020

Endosomal recycling of the Na+/H+ exchanger NHE3 isoform is regulated by the phosphatidylinositol 3-kinase pathway.

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12 December 2020

Activation of Na+/H+ exchange and Ca2+ mobilization start simultaneously in thrombin-stimulated platelets. Evidence that platelet shape change disturbs early rises of BCECF fluorescence which causes an underestimation of actual cytosolic alkalinizat

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12 December 2020

Molecular cloning, primary structure, and expression of the human growth factor-activatable Na+/H+ antiporter

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12 December 2020

Molecular cloning and physical and genetic mapping of a novel human Na+/H+ exchanger (NHE5/SLC9A5) to chromosome 16q22.1

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12 December 2020

The Na+/H+ exchange is required for platelet aggregation induced by AVP (arginine-vasopressin)

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12 December 2020

Changes of platelet functions by extracellular sodium ion

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12 December 2020

Amiloride inhibits phorbol ester-stimulated Na+/H+ exchange and protein kinase C. An amiloride analog selectively inhibits Na+/H+ exchange

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12 December 2020

Activation of Na+-H+ exchange is necessary for RhoA-induced stress fiber formation

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12 December 2020

Regulation of the phosphoinositide cycle by Na+/H+ exchange and intracellular pH in human platelets

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12 December 2020

Evidence for A role of Na+H+ exchange in platelets activated with calcium-ionophore A 23187

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12 December 2020

Molecular mechanisms of platelet activation

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12 December 2020

Activation of phospholipases A and C in human platelets exposed to epinephrine: role of glycoproteins IIb/IIIa and dual role of epinephrine

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12 December 2020

A phorbol ester and 1-oleoyl-2-acetylglycerol induce Na+/H+ exchange in human platelets

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12 December 2020

Galpha12 differentially regulates Na+-H+ exchanger isoforms.

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12 December 2020

Phorbol ester and diacylglycerol mimic growth factors in raising cytoplasmic pH

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12 December 2020

[Effect of adenylate cyclase system activation on Na+/H+-exchange in human platelets]

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12 December 2020

Structure function of the growth factor-activatable Na+/H+ exchanger (NHE1)

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12 December 2020

Alpha-thrombin, epidermal growth factor, and okadaic acid activate the Na+/H+ exchanger, NHE-1, by phosphorylating a set of common sites

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12 December 2020

Phosphorylation of the C-terminal domain of the Na+/H+ exchanger by Ca2+/calmodulin-dependent protein kinase II

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12 December 2020

Simultaneous flow cytometric measurements of thrombin-induced cytosolic pH and Ca2+ fluxes in human platelets

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12 December 2020

Role of Na+/H+ exchange in thrombin- and arachidonic acid-induced Ca2+ influx in platelets

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12 December 2020

Relation between the changes in Na+/H+-exchange and cytoplasmic Ca levels in platelet activation

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12 December 2020

Potentiation by adrenaline of thrombin-induced elevation of pHi is not essential for synergistic activation of human platelets

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12 December 2020

Agonist-evoked alkaline shift in the cytosolic pH set point for activation of Na+/H+ antiport in human platelets. The role of cytosolic Ca2+ and protein kinase C.

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12 December 2020

Sodium-hydrogen exchange isoform expression in blood cells: implications for studies in diabetes mellitus

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12 December 2020

Identification of a mitochondrial Na+/H+ exchanger

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12 December 2020

Inhibition by amiloride analogues of Na+-dependent hexose uptake in LLC-PK1/Cl4 cells

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12 December 2020

Na+/H+ exchange modulates Ca2+ mobilization in human platelets stimulated by ADP and the thromboxane mimetic U 46619

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12 December 2020

Growth factors induce phosphorylation of the Na+/H+ antiporter, glycoprotein of 110 kD

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12 December 2020

Role of Na(+)-H+ and Cl(-)-HCO3- antiports in the regulation of cytosolic pH near neutrality

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12 December 2020

Molecular cloning and functional expression of a rat Na+/H+ exchanger (NHE5) highly expressed in brain

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12 December 2020

Thrombin-induced cytosolic alkalinization in human platelets occurs without an apparent involvement of HCO3-/Cl- exchange

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12 December 2020

Evidence for a role for Na+-H+ exchange in activation of human platelets by PAF

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12 December 2020

pH sensitivity of the thrombin-induced rise in fructose 2,6-bisphosphate content of human platelets

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12 December 2020

Agonist-evoked changes in cytosolic pH and calcium concentration in human platelets: studies in physiological bicarbonate

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12 December 2020

Hypertensive sodium-proton exchanger phenotype persists in immortalized lymphoblasts from essential hypertensive patients. A cell culture model for human hypertension

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12 December 2020

Enhanced mitogen-activated protein kinase activity and phosphorylation of the Na+/H+ exchanger isoform-1 of human lymphoblasts in hypertension

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12 December 2020

Thrombin stimulates Na+-H+exchange across the human platelet plasma membrane

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12 December 2020

Amiloride and its analogs as tools in the study of ion transport

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12 December 2020

Primary structure and functional expression of a novel gastrointestinal isoform of the rat Na/H exchanger.

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12 December 2020

The Na+/H+exchanger is phosphorylated in human platelets in response to activating agents

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12 December 2020

Synthesis of the highly selective Na+/H+ exchange inhibitors cariporide mesilate and (3-methanesulfonyl-4-piperidino-benzoyl) guanidine methanesulfonate.

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12 December 2020

Regulation of platelet function by sodium-hydrogen exchange

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12 December 2020

Calmodulin-binding autoinhibitory domain controls "pH-sensing" in the Na+/H+ exchanger NHE1 through sequence-specific interaction

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12 December 2020

Na+/H+ exchange and cytoplasmic pH in the action of growth factors in human fibroblasts

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12 December 2020

Thrombin-induced changes of intracellular [Ca2+] and pH in human platelets. Cytoplasmic alkalinization is not a prerequisite for calcium mobilization

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12 December 2020

Topological analysis of NHE1, the ubiquitous Na+/H+ exchanger using chymotryptic cleavage

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12 December 2020

Cloning and expression of a rabbit cDNA encoding a serum-activated ethylisopropylamiloride-resistant epithelial Na+/H+ exchanger isoform (NHE-2).

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12 December 2020

Na+/H+ exchangers of mammalian cells.

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12 December 2020

Cloning, tissue distribution, and functional analysis of the human Na+/N+ exchanger isoform, NHE3

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12 December 2020

G proteins of the G12 family are activated via thromboxane A2 and thrombin receptors in human platelets

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12 December 2020

Membrane sodium-proton exchange and primary hypertension

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12 December 2020

Inhibition of platelet aggregation by amiloride

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12 December 2020

Mechanism of cardiac T-type Ca channel blockade by amiloride

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12 December 2020

The Na+/H+ exchanger isoform 1 (NHE1) is a novel member of the calmodulin-binding proteins. Identification and characterization of calmodulin-binding sites

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12 December 2020

Inhibition of thrombin and SFLLR-peptide stimulation of platelet aggregation, phospholipase A2 and Na+/H+ exchange by a thrombin receptor antagonist

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12 December 2020

G alpha 13 stimulates Na+-H+ exchange through distinct Cdc42-dependent and RhoA-dependent pathways

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12 December 2020

Na+/H+ exchange and growth factor-induced cytosolic pH changes. Role in cellular proliferation

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12 December 2020

Characterization of Na+/H+ exchange in platelets

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12 December 2020

Ca2+ mobilization can occur independent of acceleration of Na+/H+ exchange in thrombin-stimulated human platelets

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12 December 2020

p160ROCK mediates RhoA activation of Na-H exchange

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12 December 2020

Removal of extraplatelet Na+ eliminates indomethacin-sensitive secretion from human platelets stimulated by epinephrine, ADP, and thrombin

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12 December 2020

Activation of sodium–proton exchange is a prerequisite for Ca2+ mobilization in human platelets

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12 December 2020

Inhibition of Na+/Ca2+ exchange in membrane vesicle and papillary muscle preparations from guinea pig heart by analogs of amiloride

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12 December 2020

Thrombin-induced platelet aggregation is affected by external Na+ independently of the Na+/H+ exchange

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12 December 2020

Na+/H+ exchange in PAF-stimulated platelets

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12 December 2020

A calcineurin homologous protein inhibits GTPase-stimulated Na-H exchange

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12 December 2020

Higher Na+???H+ exchange rate and more alkaline intracellular pH set-point in essential hypertension: effects of protein kinase modulation in platelets

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12 December 2020

Molecular cloning of putative members of the Na/H exchanger gene family. cDNA cloning, deduced amino acid sequence, and mRNA tissue expression of the rat Na/H exchanger NHE-1 and two structurally related proteins

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12 December 2020

Angiotensin II stimulates p90rsk in vascular smooth muscle cells. A potential Na(+)-H+ exchanger kinase

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12 December 2020

Platelet Na(+)-H+ exchanger activity in normotensive and hypertensive subjects: effect of enalapril therapy upon antiport activity

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12 December 2020

Estimation of carrier density and turnover rate of the Na+/H+ exchanger in human platelets using 5-(N-methyl-N-[3H]isobutyl)amiloride

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12 December 2020

Stimulation of mitogen-activated protein kinase and Na+/H+ exchanger in human platelets. Differential effect of phorbol ester and vasopressin

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12 December 2020

Mutation of calmodulin-binding site renders the Na+/H+ exchanger (NHE1) highly H(+)-sensitive and Ca2+ regulation-defective

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12 December 2020

Molecular cloning, sequencing, tissue distribution, and functional expression of a Na+/H+ exchanger (NHE-2)

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12 December 2020

A point mutation of the Na+/H+ exchanger gene (NHE1) and amplification of the mutated allele confer amiloride resistance upon chronic acidosis

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12 December 2020

Growth factor activation and "H(+)-sensing" of the Na+/H+ exchanger isoform 1 (NHE1). Evidence for an additional mechanism not requiring direct phosphorylation

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12 December 2020

Amiloride-sensitive Na+-H+ exchange in platelets and leukocytes: detection by electronic cell sizing

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12 December 2020

Evidence that Na+/H+ exchange regulates receptor-mediated phospholipase A2 activation in human platelets

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12 December 2020

Effects of sodium removal on calcium mobilization and dense granule secretion induced by thrombin in human platelets

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12 December 2020

The p42/p44 mitogen-activated protein kinase cascade is determinant in mediating activation of the Na+/H+ exchanger (NHE1 isoform) in response to growth factors

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12 December 2020

Effects of changes in intracellular pH induced by platelet storage and treatment with monovalent cation ionophores on platelet functions

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12 December 2020

Modification of Na+/H+ exchanger in human platelets by 1,2-dioctanoylglycerol, a protein kinase C activator

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12 December 2020

G alpha 12 and G alpha 13 stimulate Rho-dependent stress fiber formation and focal adhesion assembly

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12 December 2020

Molecular physiology of vertebrate Na+/H+ exchangers

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12 December 2020

The intracellular pH of the human platelet

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12 December 2020

Effects of angiotensin II and endothelin-1 on platelet aggregation and cytosolic pH and free Ca2+ concentrations in essential hypertension

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12 December 2020

Protein kinase C-dependent and -independent activation of Na+/H+ exchanger by G alpha 12 class of G proteins.

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12 December 2020

Pharmacological characterization of stably transfected Na+/H+ antiporter isoforms using amiloride analogs and a new inhibitor exhibiting anti-ischemic properties.

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12 December 2020

Regulation of intracellular pH in human platelets. Effects of thrombin, A23187, and ionomycin and evidence for activation of Na+/H+ exchange and its inhibition by amiloride analogs

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12 December 2020

Intracellular calcium mobilization and activation of the Na+/H+ exchanger in platelets

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12 December 2020

Hormonal regulation, pharmacology, and membrane sorting of vertebrate Na+/H+ exchanger isoforms

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12 December 2020

Changes in Cytoplasmic pH and in Membrane Potential in Thrombin-Stimulated Human Platelets

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12 December 2020

Protective effects of HOE642, a selective sodium-hydrogen exchange subtype 1 inhibitor, on cardiac ischaemia and reperfusion

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12 December 2020

Vasopressin elevation of Na+/H+ exchange is inhibited by genistein in human blood platelets

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12 December 2020

Effects of the Na+/H+-exchange inhibitor Hoe 642 on intracellular pH, calcium and sodium in isolated rat ventricular myocytes

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12 December 2020

Extracellular Na+ removal enhances granule secretion in platelets--evidence that Na+/H+ exchange is inhibitory to secretion induced by some agonists

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12 December 2020

Sodium fluoride prevents receptor- and protein kinase C-mediated activation of the human platelet Na+/H+ exchanger without inhibiting its basic pHi-regulating activity

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12 December 2020

G alpha 13 stimulates Na-H exchange.

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12 December 2020

G-protein stimulation inhibits amiloride-sensitive Na/H exchange independently of cyclic AMP

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12 December 2020

Comparison between sodium-hydrogen ion and lithium-hydrogen ion exchange in human platelets

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12 December 2020

Effect of epinephrine on the regulation of Na+/H+ exchange in human platelets

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12 December 2020

Cloning and sequencing of a rabbit cDNA encoding an intestinal and kidney-specific Na+/H+ exchanger isoform (NHE-3)

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12 December 2020

Resting and ADP-evoked changes in cytosolic free sodium concentration in human platelets loaded with the indicator SBFI.

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12 December 2020

Aspirin does not inhibit adenosine diphosphate-induced platelet alpha-granule release

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12 December 2020

Na(+)-H+ exchange and essential hypertension. A new approach

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12 December 2020

Identification of a sodium-bicarbonate symport in human platelets

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12 December 2020

Phosphorylation and regulation of the Na+/H+ exchanger through mitogen-activated protein kinase

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12 December 2020

Activation of Na+/H+ exchange in human platelets stimulated by thrombin and a phorbol ester

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12 December 2020

Induction of tyrosine phosphorylation and Na+/H+ exchanger activation during shrinkage of human neutrophils

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12 December 2020

Na-H exchange acts downstream of RhoA to regulate integrin-induced cell adhesion and spreading

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12 December 2020

A 90-kD Na(+)-H+ exchanger kinase has increased activity in spontaneously hypertensive rat vascular smooth muscle cells

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12 December 2020

Inhibitors of Na+/H+ exchange block stimulus-provoked arachidonic acid release in human platelets. Selective effects on platelet activation by epinephrine, ADP, and lower concentrations of thrombin

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12 December 2020

Intracellular pH regulation in leukocytes: mechanisms and functional significance.

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12 December 2020

Expression of Na(+)-H+ exchanger isoforms NHE1 and NHE3 in kidney and blood cells of rabbit and rat

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12 December 2020

Effects of amiloride on the response of human platelets to bovine α thrombin

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12 December 2020

Cytoplasmic pH dependency of Na+/H+ exchange in human platelets activated with thrombin, arachidonic acid, A23187 and TPA

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12 December 2020

Direct characterization of the Na+/H+ exchanger in human platelets

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12 December 2020

Identifiers

DOI

10.1023/A:1008986329267

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Dimensions Publication ID

29 July 2017

1034109740

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