(Q33731904)

29 July 2017

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title

Neuroregulation of ProTRH biosynthesis and processing (English)

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29 July 2017

Nillni EA

1

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29 July 2017

publication date

1 June 1999

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29 July 2017

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29 July 2017

volume

10

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29 July 2017

issue

3

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29 July 2017

page(s)

185-199

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Tertiary hypothyroidism and hyperglycemia in mice with targeted disruption of the thyrotropin-releasing hormone gene

29 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FBF02738618

Neuroendocrine regulation of thyrotropin-releasing hormone (TRH) in the tuberoinfundibular system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02738618

Proteolytic processing mechanisms in the biosynthesis of neuroendocrine peptides: the subtilisin-like proprotein convertases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02738618

Enzymic characterization of murine and human prohormone convertase-1 (mPC1 and hPC1) expressed in mammalian GH4C1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02738618

Carboxypeptidase E activity is deficient in mice with the fat mutation. Effect on peptide processing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02738618

Sorting and storage during secretory granule biogenesis: looking backward and looking forward

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02738618

Identification of a transferable sorting domain for the regulated pathway in the prohormone convertase PC2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02738618

Identification of routing determinants in the cytosolic domain of a secretory granule-associated integral membrane protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02738618

Cloning and characterization of a cDNA encoding a novel subtype of rat thyrotropin-releasing hormone receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02738618

Desensitization of thyrotropin-releasing hormone receptor-mediated responses involves multiple steps

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02738618

Rapid desensitization of the thyrotropin-releasing hormone receptor expressed in single human embryonal kidney 293 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02738618

Evidence that the thyrotropin-releasing hormone receptor and its ligand are recycled dissociated from each other

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02738618

Calcium- and pH-dependent aggregation of carboxypeptidase E

21 January 2018

1 reference

12 December 2020

Proinsulin processing by the subtilisin-related proprotein convertases furin, PC2, and PC3

1 reference

12 December 2020

Thyrotropin-releasing hormone: regional distribution in rat brain

1 reference

12 December 2020

Testicular expression of PC4 in the rat: molecular diversity of a novel germ cell-specific Kex2/subtilisin-like proprotein convertase

1 reference

12 December 2020

cDNA structure, tissue distribution, and chromosomal localization of rat PC7, a novel mammalian proprotein convertase closest to yeast kexin-like proteinases

1 reference

12 December 2020

Furin is a subtilisin-like proprotein processing enzyme in higher eukaryotes

1 reference

12 December 2020

Cloning and expression of the thyrotropin-releasing hormone receptor from GH3 rat anterior pituitary cells

1 reference

12 December 2020

Characterization of receptors for thyrotropin-releasing hormone-potentiating peptide on rat anterior pituitary membranes

1 reference

12 December 2020

Light and electron microscopic immunocytochemistry of neurotensin-like immunoreactive neurons in the rat hypothalamus

1 reference

12 December 2020

Preprothyrotropin-releasing hormone mRNA in the rat central gray is strongly and persistently induced during morphine withdrawal

1 reference

12 December 2020

Re-routing of a secretory protein by fusion with human growth hormone sequences

1 reference

12 December 2020

Increased fos-like immunoreactivity in the periaqueductal gray of anaesthetised rats during opiate withdrawal.

1 reference

12 December 2020

A study of a highly specific pyroglutamyl aminopeptidase type-II from the membrane fraction of bovine brain.

1 reference

12 December 2020

Constitutive and regulated secretion of proteins

1 reference

12 December 2020

Proprotein and prohormone convertases of the subtilisin family Recent developments and future perspectives

1 reference

12 December 2020

Expression of the proprotein convertases PC1 and PC2 mRNAs in thyrotropin releasing hormone neurons of the rat paraventricular nucleus of hypothalamus

1 reference

12 December 2020

The family of subtilisin/kexin like pro-protein and pro-hormone convertases: divergent or shared functions

1 reference

12 December 2020

Multifactorial modulation of TRH metabolism

1 reference

12 December 2020

Processing of thyrotropin-releasing hormone (TRH) prohormone in the rat olfactory bulb generates novel TRH-related peptides.

1 reference

12 December 2020

Extrahypothalamic Thyrotropin Releasing Hormone (TRH) — Its distribution and its functions

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12 December 2020

Glucocorticoids stimulate thyrotropin-releasing hormone gene expression in cultured hypothalamic neurons

1 reference

12 December 2020

Processing of prothyrotropin-releasing hormone (Pro-TRH) by bovine intermediate lobe secretory vesicle membrane PC1 and PC2 enzymes

1 reference

12 December 2020

Kex2-like endoproteases PC2 and PC3 accurately cleave a model prohormone in mammalian cells: evidence for a common core of neuroendocrine processing enzymes

1 reference

12 December 2020

The proprotein convertases

1 reference

12 December 2020

The propeptide of preprosomatostatin mediates intracellular transport and secretion of alpha-globin from mammalian cells

1 reference

12 December 2020

Neuroendocrine control of thyrotropin secretion

1 reference

12 December 2020

Agonist-stimulated internalization of the thyrotropin-releasing hormone receptor is dependent on two domains in the receptor carboxyl terminus

1 reference

12 December 2020

Immunohistochemical localization of thyrotropin-releasing hormone in the rat hypothalamus and pituitary

1 reference

12 December 2020

Comparative proteolytic processing of rat prosomatostatin by the convertases PC1, PC2, furin, PACE4 and PC5 in constitutive and regulated secretory pathways

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12 December 2020

Processing of proenkephalin is tissue-specific

1 reference

12 December 2020

CCK biosynthesis and processing: recent progress and future challenges

1 reference

12 December 2020

Evidence for alpha 1-adrenergic stimulatory control of in vitro release of immunoreactive thyrotropin-releasing hormone from rat median eminence: in vivo corroboration

1 reference

12 December 2020

Mannose 6-phosphate receptors are sorted from immature secretory granules via adaptor protein AP-1, clathrin, and syntaxin 6-positive vesicles

1 reference

12 December 2020

The disulfide bond in chromogranin B, which is essential for its sorting to secretory granules, is not required for its aggregation in the trans-Golgi network

1 reference

12 December 2020

Role of TRH in seizure modulation.

1 reference

12 December 2020

Identification of the thyrotropin-releasing hormone-prohormone and its posttranslational processing in a transfected AtT20 tumoral cell line

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12 December 2020

Leptin inhibition of the hypothalamic-pituitary-adrenal axis in response to stress

1 reference

12 December 2020

The arcuate nucleus is the major source for neuropeptide Y-innervation of thyrotropin-releasing hormone neurons in the hypothalamic paraventricular nucleus

1 reference

12 December 2020

Distribution of TRH-potentiating peptide (Ps4) and its receptors in rat brain and peripheral tissues

1 reference

12 December 2020

Analysis of structural requirements for TRH-potentiating peptide receptor binding by analogue design

1 reference

12 December 2020

Thyrotropin-releasing hormone precursor: characterization in rat brain

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12 December 2020

Cloning and sequence analysis of cDNA encoding rat carboxypeptidase D.

1 reference

12 December 2020

Molecular dissection of the secretory pathway

1 reference

12 December 2020

Specificity of a Serum Peptidase Hydrolyzing Thyroliberin at the Pyroglutamyl-Histidine Bond

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12 December 2020

Neuroendocrine and autonomous mechanisms underlying thermoregulation in cold environment

1 reference

12 December 2020

Central respiratory stimulant effect by thyrotropin in releasing hormone in the rat

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12 December 2020

Distribution of TRH-like immunoreactivity with special reference to coexistence with other neuroactive compounds

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12 December 2020

Inhibition of hypothalamic thyrotropin-releasing hormone messenger ribonucleic acid during food deprivation

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12 December 2020

Adenohypophyseal degradation of thyrotropin releasing hormone regulated by thyroid hormones

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12 December 2020

Regional distribution of pyroglutamyl peptidase II in rabbit brain, spinal cord, and organs

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12 December 2020

Processing of proTRH to its intermediate products occurs before the packing into secretory granules of transfected AtT20 cells

1 reference

12 December 2020

Role of the hypothalamic paraventricular nucleus in the secretion of thyrotropin under adrenergic and cold-stimulated conditions in the rat.

1 reference

12 December 2020

Identification of the sorting signal motif within pro-opiomelanocortin for the regulated secretory pathway

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12 December 2020

Structure and function of eukaryotic proprotein processing enzymes of the subtilisin family of serine proteases.

1 reference

12 December 2020

On the neuropharmacology of thyrotropin releasing hormone (TRH)

1 reference

12 December 2020

Alterations in mRNA of enkephalin, dynorphin and thyrotropin releasing hormone during amygdala kindling: an in situ hybridization study

1 reference

12 December 2020

Immunocytochemical distribution in rat brain of putative peptides derived from thyrotropin-releasing hormone prohormone

1 reference

12 December 2020

Cellular localization of the prohormone convertases in the hypothalamic paraventricular and supraoptic nuclei: selective regulation of PC1 in corticotrophin-releasing hormone parvocellular neurons mediated by glucocorticoids

1 reference

12 December 2020

Biosynthesis and posttranslational processing of the neurotensin/neuromedin N precursor in the rat medullary thyroid carcinoma 6-23 cell line. Effect of dexamethasone

1 reference

12 December 2020

Involvement of adrenergic receptor mechanisms within hypothalamus in the fever induced by amphetamine and thyrotropin-releasing hormone in the rat

1 reference

12 December 2020

Cloning and characterization of a new subtype of thyrotropin-releasing hormone receptors

1 reference

12 December 2020

Circadian and pulsatile thyrotropin secretion in euthyroid man under the influence of thyroid hormone and glucocorticoid administration

1 reference

12 December 2020

Responses of anterior hypothalamic-preoptic thermosensitive neurons to thyrotropin releasing hormone and cyclo(His-Pro)

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12 December 2020

Corticotropin release inhibiting factor is encoded within prepro-TRH.

1 reference

12 December 2020

A prepro-TRH connecting peptide (prepro-TRH 160-169) potentiates TRH-induced TSH release from rat perifused pituitaries by stimulating dihydropyridine- and omega-conotoxin-sensitive Ca2+ channels

1 reference

12 December 2020

Effect of 6-hydroxydopamine treatment on TSH secretion in basal and cold-stimulated conditions in the rat

1 reference

12 December 2020

Thyrotropin-releasing hormone: basis and potential for its therapeutic use.

1 reference

12 December 2020

Protein hormone storage in secretory granules: mechanisms for concentration and sorting

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12 December 2020

Molecular and cellular biology of thyrotropin-releasing hormone receptors

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12 December 2020

Pituitary TRH receptors

1 reference

12 December 2020

Glucocorticoids modulate the biosynthesis and processing of prothyrotropin releasing-hormone (proTRH).

1 reference

12 December 2020

Prohormone processing in the trans-Golgi network: endoproteolytic cleavage of prosomatostatin and formation of nascent secretory vesicles in permeabilized cells

1 reference

12 December 2020

Thyrotropin-releasing hormone (TRH): distribution in hypothalamic and extrahypothalamic brain tissues of mammalian and submammalian chordates

1 reference

12 December 2020

Identification of the thyrotropin-releasing hormone precursor, its processing products, and its coexpression with convertase 1 in primary cultures of hypothalamic neurons: anatomic distribution of PC1 and PC2.

1 reference

12 December 2020

Somatostatin connections between the hypothalamus and the limbic system of the rat brain.

1 reference

12 December 2020

Pro‐Thyrotropin‐Releasing Hormone Processing by Recombinant PC1

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12 December 2020

The organization of forebrain afferents to the paraventricular and supraoptic nuclei of the rat.

1 reference

12 December 2020

Signal transduction, desensitization, and recovery of responses to thyrotropin-releasing hormone after inhibition of receptor internalization

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12 December 2020

Some Events of Thyrotropin-Releasing Hormone Metabolism Are Regulated in Lactating and Cycling Rats

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12 December 2020

Processing of thyrotropin-releasing hormone prohormone (pro-TRH) generates a biologically active peptide, prepro-TRH-(160-169), which regulates TRH-induced thyrotropin secretion

1 reference

12 December 2020

Stimulation of prolactin and growth hormone release by TRH infused into a hypophysial portal vessel.

1 reference

12 December 2020

Proteolytic processing of pro-ACTH/endorphin begins in the Golgi complex of pituitary corticotropes and AtT-20 cells

1 reference

12 December 2020

Prohormone-converting enzymes: regulation and evaluation of function using antisense RNA.

1 reference

12 December 2020

Thyroid-stimulating Hormone Response to Synthetic Thyrotrophin-releasing Hormone in Man

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12 December 2020

Triiodothyronine exerts direct cell-specific regulation of thyrotropin-releasing hormone gene expression in the hypothalamic paraventricular nucleus

1 reference

12 December 2020

Pituitary thyrotropin-releasing hormone (TRH) receptors: effects of TRH, drugs mimicking TRH action, and chlordiazepoxide.

1 reference

12 December 2020

Altered processing of procholecystokinin in carboxypeptidase E-deficient fat mice: differential synthesis in neurons and endocrine cells.

1 reference

12 December 2020

Eukaryotic protein processing: endoproteolysis of precursor proteins

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12 December 2020

SPC4, SPC6, and the novel protease SPC7 are coexpressed with bone morphogenetic proteins at distinct sites during embryogenesis.

1 reference

12 December 2020

Release of pro-thyrotropin-releasing hormone connecting peptides PS4 and PS5 from perifused rat hypothalamic slices

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12 December 2020

Leptin prevents fasting-induced suppression of prothyrotropin-releasing hormone messenger ribonucleic acid in neurons of the hypothalamic paraventricular nucleus

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12 December 2020

Localization of immunoreactive thyrotropin releasing hormone in the lower brainstem of the rat.

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12 December 2020

Cold exposure elevates thyrotropin-releasing hormone gene expression in medullary raphe nuclei: relationship with vagally mediated gastric erosions

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12 December 2020

Pathways of protein secretion in eukaryotes

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12 December 2020

Reduction of the disulfide bond of chromogranin B (secretogranin I) in the trans-Golgi network causes its missorting to the constitutive secretory pathways.

1 reference

12 December 2020

The amino-terminal sequence of pro-opiomelanocortin directs intracellular targeting to the regulated secretory pathway

1 reference

12 December 2020

Prolactin and thyrotropin release in man by synthetic pyroglutamyl-histidyl-prolinamide

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12 December 2020

Secretory protein traffic. Chromogranin A contains a dominant targeting signal for the regulated pathway

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12 December 2020

Changes in adrenal status affect hypothalamic thyrotropin-releasing hormone gene expression in parallel with corticotropin-releasing hormone

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12 December 2020

Hyperproinsulinaemia in obese fat/fat mice associated with a carboxypeptidase E mutation which reduces enzyme activity

1 reference

12 December 2020

Carboxypeptidase E is a regulated secretory pathway sorting receptor: genetic obliteration leads to endocrine disorders in Cpe(fat) mice

1 reference

12 December 2020

Developmental changes of pyroglutamate-peptidase I activity in several regions of the female and the male rat brain.

1 reference

12 December 2020

Molecular cloning of a functional human thyrotropin-releasing hormone receptor

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12 December 2020

Calcium sequestration in the Golgi apparatus of cultured mammalian cells revealed by laser scanning confocal microscopy and ion microscopy

1 reference

12 December 2020

Physiological evidence for alpha 1-adrenergic facilitatory control of the cold-induced TRH release in the rat, obtained by push-pull cannulation of the median eminence

1 reference

12 December 2020

Is Ps4 (prepro-TRH [160-169]) more than an enhancer for thyrotropin-releasing hormone?

1 reference

12 December 2020

Dynamic measurement of the pH of the Golgi complex in living cells using retrograde transport of the verotoxin receptor

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12 December 2020

Identification of a human insulinoma cDNA encoding a novel mammalian protein structurally related to the yeast dibasic processing protease Kex2.

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12 December 2020

Expression cloning of a cDNA encoding the mouse pituitary thyrotropin-releasing hormone receptor

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12 December 2020

Effects of TRH and a rat TSH preparation on discrete hypothalamic and forebrain catecholamine nerve terminal networks in the hypophysectomized male rat.

1 reference

12 December 2020

Amino-terminal sequences of prosomatostatin direct intracellular targeting but not processing specificity

1 reference

12 December 2020

TRH gene products are implicated in the antidepressant mechanisms of seizures

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12 December 2020

Decreased levels of internalized thyrotropin-releasing hormone receptors after uncoupling from guanine nucleotide-binding protein and phospholipase-C.

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12 December 2020

Structural elements of PC2 required for interaction with its helper protein 7B2.

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12 December 2020

Thyroid hormones modulate thyrotropin-releasing hormone biosynthesis in tissues outside the hypothalamic-pituitary axis of male rats

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12 December 2020

Structure and Biosynthesis of Pro-Adrenocorticotropin/Endorphin and Related Peptides*

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12 December 2020

Prepro-TRH-(160-169) potentiates gastric acid secretion stimulated by TRH microinjected into the dorsal motor nucleus of the vagus

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12 December 2020

Influence of thyroid status on TRH metabolism in rat olfactory bulb

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12 December 2020

Central role of brown adipose tissue thyroxine 5'-deiodinase on thyroid hormone-dependent thermogenic response to cold.

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12 December 2020

The physiological role of thyrotropin-releasing hormone in the regulation of thyroid-stimulating hormone and prolactin secretion in the rat

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12 December 2020

pH- and Ca(2+)-dependent aggregation property of secretory vesicle matrix proteins and the potential role of chromogranins A and B in secretory vesicle biogenesis

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12 December 2020

Presence of a membrane bound pyroglutamyl amino peptidase degrading thyrotropin releasing hormone in rat brain

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12 December 2020

Isolation and amino acid sequence of the TRH-potentiating peptide from bovine hypothalamus

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12 December 2020

Proteases and the emerging role of protease inhibitors in prohormone processing.

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12 December 2020

Purification of and kinetic studies on a narrow specificity synaptosomal membrane pyroglutamate aminopeptidase from guinea-pig brain

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12 December 2020

Heterologous processing of prosomatostatin in constitutive and regulated secretory pathways. Putative role of the endoproteases furin, PC1, and PC2

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12 December 2020

Differential expression of alpha and beta thyroid hormone receptor genes in rat brain and pituitary

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12 December 2020

Identification of a cDNA encoding a second putative prohormone convertase related to PC2 in AtT20 cells and islets of Langerhans

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12 December 2020

In vitro studies on mechanism of action of thyrotropin releasing factor

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12 December 2020

Central nervous system action of TRH to influence gastrointestinal function and ulceration

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12 December 2020

cDNA sequence of two distinct pituitary proteins homologous to Kex2 and furin gene products: tissue-specific mRNAs encoding candidates for pro-hormone processing proteinases

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12 December 2020

Prosomatostatin II processing is initiated in the trans-Golgi network of anglerfish pancreatic cells

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12 December 2020

Thyroid hormone regulates TRH biosynthesis in the paraventricular nucleus of the rat hypothalamus

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12 December 2020

Turning off the signal: desensitization of beta-adrenergic receptor function

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12 December 2020

Opiate withdrawal increases ProTRH gene expression in the ventrolateral column of the midbrain periaqueductal gray.

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12 December 2020

Release of Somatostatin and Thyrotropin-Releasing Hormone from Rat Hypothalamic Fragmentsin Vitro*

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12 December 2020

Obesity and the hypothalamus: novel peptides for new pathways

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12 December 2020

Effects of thyrotropin releasing hormone injections into different loci of rat brain on core temperature

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12 December 2020

PC1 and PC2 are proprotein convertases capable of cleaving proopiomelanocortin at distinct pairs of basic residues

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12 December 2020

Immunocytochemical delineation of thyrotrophic area: origin of thyrotropin-releasing hormone in the median eminence

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12 December 2020

Dopaminergic Control of the Rat Thyrotroph

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12 December 2020

Tissue-specific regulation of pyroglutamate aminopeptidase II activity by thyroid hormones

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12 December 2020

Milieu-induced, selective aggregation of regulated secretory proteins in the trans-Golgi network

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12 December 2020

Distribution and coexistence of corticotropin-releasing factor-, neurotensin-, enkephalin-, cholecystokinin-, galanin- and vasoactive intestinal polypeptide/peptide histidine isoleucine-like peptides in the parvocellular part of the paraventricular

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12 December 2020

Gene expression of prohormone and proprotein convertases in the rat CNS: a comparative in situ hybridization analysis

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12 December 2020

Cold exposure elevates cellular levels of messenger ribonucleic acid encoding thyrotropin-releasing hormone in paraventricular nucleus despite elevated levels of thyroid hormones.

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12 December 2020

Differential coexpression of genes encoding prothyrotropin-releasing hormone (pro-TRH) and prohormone convertases (PC1 and PC2) in rat brain neurons: implications for differential processing of pro-TRH.

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12 December 2020

Thyrotrophin releasing hormone: endocrine and central effects

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12 December 2020

Distribution and regulation of the prohormone convertases PC1 and PC2 in the rat pituitary

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12 December 2020

Constitutive and basal secretion from the endocrine cell line, AtT-20

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12 December 2020

Distribution, cellular localization, and ontogeny of preprothyrotropin-releasing hormone-(160-169) (Ps4)-binding sites in the rat pituitary

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12 December 2020

Effects of dexamethasone on TRH, TRH-glycine and pre-pro-TRH (178-199) levels in various rat organs

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12 December 2020

Substance P and behavior: Opposite effects of N-terminal and C-terminal fragments

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12 December 2020

TRH: a possible mediator of thermoregulation

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12 December 2020

Dexamethasone inhibits corticotropin-releasing factor gene expression in the rat paraventricular nucleus

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12 December 2020

Vasoactive intestinal polypeptide/peptide histidine isoleucine immunoreactive neuron systems in the basal hypothalamus of the rat with special reference to the portal vasculature: an immunohistochemical and in situ hybridization study

1 reference

12 December 2020

Visualization of the thyrotropin-releasing hormone receptor and its ligand during endocytosis and recycling

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12 December 2020

Thyrotropin releasing hormone (TRH): neurotransmitter regulation of secretion by mouse hypothalamic tissue in vitro

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12 December 2020

Quantitative autoradiography of TRH receptors in discrete brain regions of different mammalian species

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12 December 2020

Depletion of carboxypeptidase E, a regulated secretory pathway sorting receptor, causes misrouting and constitutive secretion of proinsulin and proenkephalin, but not chromogranin A.

1 reference

12 December 2020

Modulation of brown adipose tissue-mediated thermogenesis by lesions to the nucleus tractus solitarius in the rat.

1 reference

12 December 2020

Preprothyrotropin-releasing hormone-(178-199) does not inhibit corticotropin release

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12 December 2020

Immunolocalization of the thyrotropin-releasing hormone prohormone in the rat central nervous system

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12 December 2020

Cloning and primary sequence of a mouse candidate prohormone convertase PC1 homologous to PC2, Furin, and Kex2: distinct chromosomal localization and messenger RNA distribution in brain and pituitary compared to PC2.

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF02738618

1 reference

29 July 2017

1 reference