(Q33733363)

29 July 2017

title

Involvement of caspase activation in azaspiracid-induced neurotoxicity in neocortical neurons (English)

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29 July 2017

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Zhengyu Cao

1

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29 July 2017

Keith T LePage

2

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29 July 2017

Michael O Frederick

3

1 reference

29 July 2017

Kyriacos C Nicolaou

4

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29 July 2017

Thomas F Murray

5

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29 July 2017

publication date

4 January 2010

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29 July 2017

published in

Toxicological Sciences

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29 July 2017

volume

114

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29 July 2017

issue

2

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29 July 2017

page(s)

323-334

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Azaspiracid substituent at C1 is relevant to in vitro toxicity

29 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840215

Brevetoxin-induced phosphorylation of Pyk2 and Src in murine neocortical neurons involves distinct signaling pathways

21 June 2018

1 reference

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Irreversible cytoskeletal disarrangement is independent of caspase activation during in vitro azaspiracid toxicity in human neuroblastoma cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840215

Cytotoxic and cytoskeletal effects of azaspiracid-1 on mammalian cell lines

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840215

Azaspiracid-4 inhibits Ca2+ entry by stored operated channels in human T lymphocytes.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840215

Effects of Azaspiracids 2 and 3 on intracellular cAMP, [Ca2+], and pH.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840215

Structural revision and total synthesis of azaspiracid-1, part 2: definition of the ABCD domain and total synthesis.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840215

Structural revision and total synthesis of azaspiracid-1, part 1: intelligence gathering and tentative proposal

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840215

Na+, K+-ATPase: the new face of an old player in pathogenesis and apoptotic/hybrid cell death

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840215

The first identification of azaspiracids in shellfish from France and Spain.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840215

First evidence of an extensive northern European distribution of azaspiracid poisoning (AZP) toxins in shellfish.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840215

Azaspiracid-1, a potent, nonapoptotic new phycotoxin with several cell targets.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840215

Determination of azaspiracids in shellfish using liquid chromatography/tandem electrospray mass spectrometry

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840215

Extranuclear apoptosis. The role of the cytoplasm in the execution phase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840215

Mechanisms for synchronous calcium oscillations in cultured rat cerebellar neurons.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840215

Spontaneous calcium transients regulate neuronal plasticity in developing neurons

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840215

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840215

Spontaneous synchronized calcium oscillations in neocortical neurons in the presence of physiological [Mg(2+)]: involvement of AMPA/kainate and metabotropic glutamate receptors

21 June 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP312

Distinct aspects of neuronal differentiation encoded by frequency of spontaneous Ca2+ transients

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP312

Azaspiracid-1 inhibits bioelectrical activity of spinal cord neuronal networks.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP312

Cleavage of cytoskeletal proteins by caspases during ovarian cell death: evidence that cell-free systems do not always mimic apoptotic events in intact cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP312

Total synthesis and structural elucidation of azaspiracid-1. Final assignment and total synthesis of the correct structure of azaspiracid-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP312

Optical monitoring of excitatory synaptic activity between cultured hippocampal neurons by a multi-site Ca2+ fluorometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP312

The c-Jun-N-terminal kinase is involved in the neurotoxic effect of azaspiracid-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP312

Effects of azaspiracid-1, a potent cytotoxic agent, on primary neuronal cultures. A structure-activity relationship study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP312

Ionic mechanism of ouabain-induced concurrent apoptosis and necrosis in individual cultured cortical neurons.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840215

Total Synthesis and Structural Elucidation of Azaspiracid-1. Synthesis-Based Analysis of Originally Proposed Structures and Indication of Their Non-Identity to the Natural Product

30 October 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP312

Total synthesis and confirmation of the revised structures of azaspiracid-2 and azaspiracid-3

21 January 2018

1 reference

12 December 2020

Chronic effects in mice caused by oral administration of sublethal doses of azaspiracid, a new marine toxin isolated from mussels

1 reference

12 December 2020

Quantitative determination of glutamate mediated cortical neuronal injury in cell culture by lactate dehydrogenase efflux assay

1 reference

12 December 2020

Structures of Azaspiracid Analogs, Azaspiracid-4 and Azaspiracid-5, Causative Toxins of Azaspiracid Poisoning in Europe

1 reference

12 December 2020

Total synthesis and structural elucidation of azaspiracid-1. Construction of key building blocks for originally proposed structure

1 reference

12 December 2020

Multiple organ damage caused by a new toxin azaspiracid, isolated from mussels produced in Ireland

1 reference

12 December 2020

Identifiers

DOI

10.1093/TOXSCI/KFP312

1 reference

29 July 2017

1 reference

29 July 2017

1 reference