(Q33738294)

29 July 2017

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title

Intestinal peptide transport systems and oral drug availability (English)

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29 July 2017

Yang CY

1

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29 July 2017

Dantzig AH

series ordinal

2

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29 July 2017

Pidgeon C

series ordinal

3

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29 July 2017

publication date

1 September 1999

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29 July 2017

published in

Pharmaceutical Research

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29 July 2017

volume

16

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29 July 2017

issue

9

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29 July 2017

page(s)

1331-1343

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The oligopeptide transport system of Bacillus subtilis plays a role in the initiation of sporulation

29 July 2017

cites work

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12 December 2020

Human intestinal H+/peptide cotransporter. Cloning, functional expression, and chromosomal localization

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12 December 2020

Intestinal absorption of dipeptides and beta-lactam antibiotics. II. Purification of the binding protein for dipeptides and beta-lactam antibiotics from rabbit small intestinal brush border membranes

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12 December 2020

The dipeptide permease of Escherichia coli closely resembles other bacterial transport systems and shows growth-phase-dependent expression

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12 December 2020

The spo0K locus of Bacillus subtilis is homologous to the oligopeptide permease locus and is required for sporulation and competence

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12 December 2020

Functional expression of transporter for beta-lactam antibiotics and dipeptides in Xenopus laevis oocytes injected with messenger RNA from human, rat and rabbit small intestines.

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12 December 2020

Peptide uptake by Salmonella typhimurium. The periplasmic oligopeptide-binding protein

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12 December 2020

Dipeptide transport in brush-border membrane vesicles (BBMV) prepared from human full-term placentae

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12 December 2020

Expression cloning and functional characterization of the kidney cortex high-affinity proton-coupled peptide transporter

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12 December 2020

A Common Mechanism for Transport of Di- and Tri-Peptides by Hamster Jejunum in Vitro

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12 December 2020

Peptide transport by the multidrug resistance pump

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12 December 2020

Membrane topology of the di- and tripeptide transport protein of Lactococcus lactis.

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12 December 2020

Transport mechanisms responsible for the absorption of loracarbef, cefixime, and cefuroxime axetil into human intestinal Caco-2 cells

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12 December 2020

Peptide chemotaxis in E. coli involves the Tap signal transducer and the dipeptide permease

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12 December 2020

CHL1 encodes a component of the low-affinity nitrate uptake system in Arabidopsis and shows cell type-specific expression in roots.

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12 December 2020

Identification of a renal cell line that constitutively expresses the kidney‐sp ecific high‐affinity H + /peptide cotransporter

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12 December 2020

Cloning of an Arabidopsis histidine transporting protein related to nitrate and peptide transporters.

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12 December 2020

Functional analysis of a chimeric mammalian peptide transporter derived from the intestinal and renal isoforms

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12 December 2020

Cefaclor uptake by the proton-dependent dipeptide transport carrier of human intestinal Caco-2 cells and comparison to cephalexin uptake

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12 December 2020

Transepithelial transport properties of peptidomimetic thrombin inhibitors in monolayers of a human intestinal cell line (Caco-2) and their correlation to in vivo data

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12 December 2020

Amplified expression, purification and functional reconstitution of the dipeptide and tripeptide transport protein of Lactococcus lactis.

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12 December 2020

Use of the peptide carrier system to improve the intestinal absorption of L-alpha-methyldopa: carrier kinetics, intestinal permeabilities, and in vitro hydrolysis of dipeptidyl derivatives of L-alpha-methyldopa

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12 December 2020

Molecular identification of a role for tyrosine 167 in the function of the human intestinal proton- coupled dipeptide transporter (hPepT1).

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12 December 2020

Cloning and functional expression of a brain peptide/histidine transporter

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12 December 2020

Tripeptide transport in rat lung

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12 December 2020

Electrophysiological characteristics of the proton-coupled peptide transporter PEPT2 cloned from rat brain

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12 December 2020

Dipeptide transport across rat alveolar epithelial cell monolayers.

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12 December 2020

Valacyclovir: a substrate for the intestinal and renal peptide transporters PEPT1 and PEPT2.

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12 December 2020

Peptide transport in Salmonella typhimurium: molecular cloning and characterization of the oligopeptide permease genes.

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12 December 2020

Mechanism of absorption of the dipeptide alpha-methyldopa-phe in intestinal brush-border membrane vesicles

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12 December 2020

Peptide transport and chemotaxis in Escherichia coli and Salmonella typhimurium: characterization of the dipeptide permease (Dpp) and the dipeptide-binding protein

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12 December 2020

Minimal molecular determinants of substrates for recognition by the intestinal peptide transporter

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12 December 2020

Sequence, tissue distribution and developmental changes in rat intestinal oligopeptide transporter

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12 December 2020

Genetic and biochemical characterization of the oligopeptide transport system of Lactococcus lactis

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12 December 2020

mRNA translation: influence of the 5' and 3' untranslated regions

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12 December 2020

Enhancement of intestinal transport of thyrotropin-releasing hormone via a carrier-mediated transport system by chemical modification with lauric acid

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12 December 2020

Functional expression of the intestinal peptide-proton co-transporter in Xenopus laevis oocytes

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12 December 2020

Sequence alignments of the H(+)-dependent oligopeptide transporter family PTR: inferences on structure and function of the intestinal PET1 transporter

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12 December 2020

Estimating human oral fraction dose absorbed: a correlation using rat intestinal membrane permeability for passive and carrier-mediated compounds.

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12 December 2020

Intestinal absorption mechanisms of thyrotropin-releasing hormone

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12 December 2020

Interaction of renin inhibitors with the intestinal uptake system for oligopeptides and beta-lactam antibiotics

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12 December 2020

A Bacillus subtilis dipeptide transport system expressed early during sporulation

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12 December 2020

NTR1 encodes a high affinity oligopeptide transporter in Arabidopsis.

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12 December 2020

Is intestinal peptide transport energized by a proton gradient?

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12 December 2020

Passive and carrier-mediated intestinal absorption components of two angiotensin converting enzyme (ACE) inhibitor prodrugs in rats: enalapril and fosinopril

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12 December 2020

Expression cloning of a cDNA from rabbit small intestine related to proton-coupled transport of peptides, beta-lactam antibiotics and ACE-inhibitors

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12 December 2020

The peptide transporter PepT2 is expressed in rat brain and mediates the accumulation of the fluorescent dipeptide derivative beta-Ala-Lys-Nepsilon-AMCA in astrocytes

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12 December 2020

Transepithelial transport and metabolism of thyrotropin-releasing hormone (TRH) in monolayers of a human intestinal cell line (Caco-2): evidence for an active transport component?

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12 December 2020

Functional expression of intestinal dipeptide/beta-lactam antibiotic transporter in Xenopus laevis oocytes.

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12 December 2020

Absorption of thyrotropin-releasing hormone after oral administration of TRH tartrate monohydrate in the rat, dog and human.

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12 December 2020

H+ coupled active transport of bestatin via the dipeptide transport system in rabbit intestinal brush-border membranes

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12 December 2020

Cloning of a Candida albicans peptide transport gene

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12 December 2020

Expression cloning of a mammalian proton-coupled oligopeptide transporter

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12 December 2020

Absorption of peptide and peptidomimetic drugs

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12 December 2020

Cloning and characterization of a rat H+/peptide cotransporter mediating absorption of beta-lactam antibiotics in the intestine and kidney.

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12 December 2020

Association of intestinal peptide transport with a protein related to the cadherin superfamily

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12 December 2020

Characterization of the oral absorption of some beta-lactams: effect of the alpha-amino side chain group

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12 December 2020

Role of pH gradient and membrane potential in dipeptide transport in intestinal and renal brush-border membrane vesicles from the rabbit. Studies with L-carnosine and glycyl-L-proline

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12 December 2020

The ami locus of the gram-positive bacterium Streptococcus pneumoniae is similar to binding protein-dependent transport operons of gram-negative bacteria

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12 December 2020

Expression of human intestinal dipeptide transporter in Xenopus laevis oocytes

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12 December 2020

Transport of bestatin in rat renal brush-border membrane vesicles

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12 December 2020

5'-Amino acid esters of antiviral nucleosides, acyclovir, and AZT are absorbed by the intestinal PEPT1 peptide transporter

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12 December 2020

Carrier-mediated uptake of cephalexin in human intestinal cells

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12 December 2020

Intestinal absorption studies on peptide mimetic alpha-methyldopa prodrugs

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12 December 2020

Structure-activity relationship of carbacephalosporins and cephalosporins: antibacterial activity and interaction with the intestinal proton-dependent dipeptide transport carrier of Caco-2 cells

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12 December 2020

Structural specificity of mucosal-cell transport and metabolism of peptide drugs: implication for oral peptide drug delivery

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12 December 2020

Di-tripeptides and oligopeptides are taken up via distinct transport mechanisms in Lactococcus lactis.

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12 December 2020

Structure, function, and molecular modeling approaches to the study of the intestinal dipeptide transporter PepT1.

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12 December 2020

Determination of intrinsic membrane transport parameters from perfused intestine experiments: A boundary layer approach to estimating the aqueous and unbiased membrane permeabilities

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12 December 2020

Absorption of ACE inhibitors from small intestine and colon

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12 December 2020

Molecular characterization of the oligopeptide permease of Salmonella typhimurium

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12 December 2020

Isolation and characterization of a Saccharomyces cerevisiae peptide transport gene

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12 December 2020

Dipeptide transport characteristics of the apical membrane of rat lung type II pneumocytes

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12 December 2020

H+ coupled uphill transport of aminocephalosporins via the dipeptide transport system in rabbit intestinal brush-border membranes

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12 December 2020

Clinical applications of thyrotrophin-releasing hormone

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12 December 2020

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12 December 2020

Transport mechanisms of bestatin in rabbit intestinal brush-border membranes: role of H+/dipeptide cotransport system.

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12 December 2020

DNA sequence analysis of 66 kb of the human MHC class II region encoding a cluster of genes for antigen processing

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12 December 2020

Pharmacokinetic properties of the cephalosporins

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12 December 2020

Angiotensin-converting enzyme (ACE) inhibitor transport in human intestinal epithelial (Caco-2) cells

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12 December 2020

The POT family of transport proteins

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12 December 2020

Structural studies of the H+/oligopeptide transport system from rabbit small intestine

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12 December 2020

Purification by ceftibuten-affinity chromatography and the functional reconstitution of oligopeptide transporter(s) in rat intestinal brush-border membrane

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12 December 2020

Functional interactions between synthetic alkyl phospholipids and the ABC transporters P-glycoprotein, Ste-6, MRP, and Pgh 1

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12 December 2020

Mechanisms of glycyl-L-leucine uptake by guinea-pig small intestine: relative importance of intact-peptide transport.

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12 December 2020

Molecular cloning and tissue distribution of rat peptide transporter PEPT2.

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12 December 2020

Intestinal absorption mechanism of dipeptide angiotensin converting enzyme inhibitors of the lysyl-proline type: lisinopril and SQ 29,852

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12 December 2020

Identification of the polyamine-induced protein as a periplasmic oligopeptide binding protein

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12 December 2020

The PTR family: a new group of peptide transporters

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12 December 2020

H+/Di-tripeptide transporter (PepT1) expression in the rabbit intestine

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12 December 2020

An Arabidopsis peptide transporter is a member of a new class of membrane transport proteins

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12 December 2020

An oligopeptide transporter is expressed at high levels in the pancreatic carcinoma cell lines AsPc-1 and Capan-2.

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12 December 2020

Thyrotrophin releasing hormone: endocrine and central effects

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12 December 2020

Cloning and characterization of a pH-sensing regulatory factor that modulates transport activity of the human H+/peptide cotransporter, PEPT1

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12 December 2020

Human dipeptide transporter, hPEPT1, stably transfected into Chinese hamster ovary cells

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12 December 2020

The multidrug transporters--proteins of an ancient immune system

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12 December 2020

Intestinal absorption of beta-lactam antibiotics and oligopeptides. Functional and stereospecific reconstitution of the oligopeptide transport system from rabbit small intestine

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12 December 2020

Thyrotrophin-releasing hormone. New applications in the clinic

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12 December 2020

Regulation of translation by specific protein/mRNA interactions

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12 December 2020

Mechanisms of the human intestinal H+-coupled oligopeptide transporter hPEPT1.

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12 December 2020

Conformational study of thyrotrophin-releasing hormone. I. Aspects of importance in the design of novel TRH analogues

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12 December 2020

Differential Recognition of β-Lactam Antibiotics by Intestinal and Renal Peptide Transporters, PEPT 1 and PEPT 2

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12 December 2020

The di- and tripeptide transport protein of Lactococcus lactis. A new type of bacterial peptide transporter.

1 reference

12 December 2020

Molecular cloning of PEPT 2, a new member of the H+/peptide cotransporter family, from human kidney

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12 December 2020

Identifiers

DOI

10.1023/A:1018982505021

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29 July 2017

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