(Q33739256)

29 July 2017

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title

Acute promyelocytic leukemia: from treatment to genetics and back (English)

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acute promyelocytic leukemia

29 July 2017

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Kogan SC

1

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29 July 2017

Bishop JM

series ordinal

2

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29 July 2017

language of work or name

English

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publication date

1 September 1999

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29 July 2017

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29 July 2017

volume

18

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29 July 2017

issue

38

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29 July 2017

page(s)

5261-5267

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Translocation breakpoint of acute promyelocytic leukemia lies within the retinoic acid receptor alpha locus

29 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202996

The promyelocytic leukemia protein PML has a pro-apoptotic activity mediated through its RING domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202996

Molecular analysis of acute promyelocytic leukemia breakpoint cluster region on chromosome 17

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202996

A PMLRARalpha transgene initiates murine acute promyelocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202996

Rearrangements of the retinoic acid receptor alpha and promyelocytic leukemia zinc finger genes resulting from t(11;17)(q23;q21) in a patient with acute promyelocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202996

The PML-retinoic acid receptor alpha translocation converts the receptor from an inhibitor to a retinoic acid-dependent activator of transcription factor AP-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202996

A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202996

Characterization of a Zinc Finger Gene Disrupted by the t(15;17) in Acute Promyelocytic Leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202996

Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202996

The acute promyelocytic leukemia-specific PML-RAR alpha fusion protein inhibits differentiation and promotes survival of myeloid precursor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202996

Distinct interactions of PML-RARalpha and PLZF-RARalpha with co-repressors determine differential responses to RA in APL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202996

Acute leukemia with promyelocytic features in PML/RARalpha transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202996

In vivo analysis of the molecular pathogenesis of acute promyelocytic leukemia in the mouse and its therapeutic implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202996

Structure, organization, and dynamics of promyelocytic leukemia protein nuclear bodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202996

SMRT corepressor interacts with PLZF and with the PML-retinoic acid receptor alpha (RARalpha) and PLZF-RARalpha oncoproteins associated with acute promyelocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202996

Multimeric complexes of the PML-retinoic acid receptor alpha fusion protein in acute promyelocytic leukemia cells and interference with retinoid and peroxisome-proliferator signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202996

Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202996

Application of heavy metal and cytokine for differentiation-inducing therapy in acute promyelocytic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202996

Retinoic acid and arsenic synergize to eradicate leukemic cells in a mouse model of acute promyelocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202996

Structure and Function in the Nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202996

Recombinant PML adenovirus suppresses growth and tumorigenicity of human breast cancer cells by inducing G1 cell cycle arrest and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202996

Role of the histone deacetylase complex in acute promyelocytic leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202996

The RXR heterodimers and orphan receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202996

PML, a growth suppressor disrupted in acute promyelocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202996

Targeting the PML/RAR alpha translocation product triggers apoptosis in promyelocytic leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202996

Opposite effects of the acute promyelocytic leukemia PML-retinoic acid receptor alpha (RAR alpha) and PLZF-RAR alpha fusion proteins on retinoic acid signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202996

Retinoids in cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202996

Complete remission after treatment of acute promyelocytic leukemia with arsenic trioxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202996

The unique aspects of acute promyelocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202996

Role of PML in cell growth and the retinoic acid pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202996

Retinoic acid regulates aberrant nuclear localization of PML-RAR alpha in acute promyelocytic leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202996

Fusion of retinoic acid receptor alpha to NuMA, the nuclear mitotic apparatus protein, by a variant translocation in acute promyelocytic leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202996

The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor alpha gene to a novel transcribed locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202996

7 January 2021

The PML-RARα fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202996

7 January 2021

Retinoic acid enhances colony-stimulating factor-induced clonal growth of normal human myeloid progenitor cells in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202996

7 January 2021

Mutant AF-2 domain of PML-RARalpha in retinoic acid-resistant NB4 cells: differentiation induced by RA is triggered directly through PML-RARalpha and its down-regulation in acute promyelocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202996

7 January 2021

Mapping of the human retinoic acid receptor to the q21 band of chromosome 17

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202996

7 January 2021

PMLRAR homodimers: distinct DNA binding properties and heteromeric interactions with RXR

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202996

7 January 2021

15/17 translocation, a consistent chromosomal change in acute promyelocytic leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202996

7 January 2021

Terminal megakaryocytic differentiation of TF-1 cells is induced by phorbol esters and thrombopoietin and is blocked by expression of PML/RARalpha fusion protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202996

7 January 2021

PML is essential for multiple apoptotic pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202996

7 January 2021

Acute promyelocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202996

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1202996

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Dimensions Publication ID

29 July 2017

1028782433

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1 reference