(Q33742688)

24220145

29 July 2017

title

Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts (English)

1 reference

29 July 2017

0 references

1 reference

8

1 reference

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6 June 2020

Charles M. Perou

12

1 reference

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6 June 2020

J Chuck Harrell

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24220145%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

author name string

Adam D Pfefferle

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24220145%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Jason I Herschkowitz

2

1 reference

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6 June 2020

Jerry Usary

3

1 reference

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6 June 2020

Benjamin T Spike

5

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6 June 2020

Jessica R Adams

6

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6 June 2020

Maria I Torres-Arzayus

7

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6 June 2020

Sean E Egan

9

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6 June 2020

Geoffrey M Wahl

10

1 reference

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6 June 2020

Jeffrey M Rosen

11

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6 June 2020

publication date

12 November 2013

1 reference

29 July 2017

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6 June 2020

volume

14

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6 June 2020

issue

11

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6 June 2020

page(s)

R125

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24220145%20AND%20SRC:MED&resulttype=core&format=json

Predicting drug responsiveness in human cancers using genetically engineered mice.

6 June 2020

cites work

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21 June 2018

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21 June 2018

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21 June 2018

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Cross-species genomic and functional analyses identify a combination therapy using a CHK1 inhibitor and a ribonucleotide reductase inhibitor to treat triple-negative breast cancer.

21 June 2018

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Oncogenic PI3K mutations lead to NF-κB-dependent cytokine expression following growth factor deprivation

21 June 2018

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21 June 2018

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Multiple roles of cyclin-dependent kinase 4/6 inhibitors in cancer therapy

21 June 2018

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STAT1-deficient mice spontaneously develop estrogen receptor α-positive luminal mammary carcinomas

21 June 2018

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Basal-like Breast cancer DNA copy number losses identify genes involved in genomic instability, response to therapy, and patient survival

21 June 2018

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Genomic analysis identifies unique signatures predictive of brain, lung, and liver relapse.

21 June 2018

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Comparative oncogenomics identifies breast tumors enriched in functional tumor-initiating cells

21 June 2018

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Building prognostic models for breast cancer patients using clinical variables and hundreds of gene expression signatures.

21 June 2018

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Deconstructing the molecular portraits of breast cancer

21 June 2018

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Minireview: Basal-like breast cancer: from molecular profiles to targeted therapies

21 June 2018

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Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer

21 June 2018

1 reference

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Rb deletion in mouse mammary progenitors induces luminal-B or basal-like/EMT tumor subtypes depending on p53 status

21 June 2018

1 reference

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Fibroblast growth factor receptor signaling dramatically accelerates tumorigenesis and enhances oncoprotein translation in the mouse mammary tumor virus-Wnt-1 mouse model of breast cancer

21 June 2018

1 reference

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A core MYC gene expression signature is prominent in basal-like breast cancer but only partially overlaps the core serum response

21 June 2018

1 reference

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Expression of autotaxin and lysophosphatidic acid receptors increases mammary tumorigenesis, invasion, and metastases

21 June 2018

1 reference

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CDK inhibitor p18(INK4c) is a downstream target of GATA3 and restrains mammary luminal progenitor cell proliferation and tumorigenesis

21 June 2018

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Supervised risk predictor of breast cancer based on intrinsic subtypes

21 June 2018

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In vitro and in vivo analysis of B-Myb in basal-like breast cancer

21 June 2018

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The functional loss of the retinoblastoma tumour suppressor is a common event in basal-like and luminal B breast carcinomas

21 June 2018

1 reference

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Molecular targeted therapies for breast cancer treatment

21 June 2018

1 reference

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Basal-like breast cancer: a critical review

21 June 2018

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ETV6-NTRK3 fusion oncogene initiates breast cancer from committed mammary progenitors via activation of AP1 complex

21 June 2018

1 reference

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Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors

21 June 2018

1 reference

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The mighty mouse: genetically engineered mouse models in cancer drug development

21 June 2018

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Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

21 June 2018

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Can the pharmaceutical industry reduce attrition rates?

21 June 2018

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21 June 2018

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pRb inactivation in mammary cells reveals common mechanisms for tumor initiation and progression in divergent epithelia

21 June 2018

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21 June 2018

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Expression of the ETV6-NTRK3 gene fusion as a primary event in human secretory breast carcinoma

21 June 2018

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Significance analysis of microarrays applied to the ionizing radiation response

21 June 2018

1 reference

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Molecular portraits of human breast tumours

21 June 2018

1 reference

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Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation.

21 June 2018

1 reference

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Mouse mammary tumor virus infection accelerates mammary carcinogenesis in Wnt-1 transgenic mice by insertional activation of int-2/Fgf-3 and hst/Fgf-4.

21 June 2018

1 reference

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Prostate and mammary adenocarcinoma in transgenic mice carrying a rat C3(1) simian virus 40 large tumor antigen fusion gene

21 June 2018

1 reference

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Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice

21 June 2018

1 reference

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Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: synergistic action of oncogenes in vivo

21 June 2018

1 reference

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The int-2 gene product acts as an epithelial growth factor in transgenic mice

21 June 2018

1 reference

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Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease

21 June 2018

1 reference

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Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease

21 June 2018

1 reference

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High drug attrition rates--where are we going wrong?

21 June 2018

1 reference

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Cooperation between Pik3ca and p53 mutations in mouse mammary tumor formation.

30 October 2018

1 reference

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Characterization of mammary tumors from Brg1 heterozygous mice.

30 October 2018

1 reference

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Characterization of medroxyprogesterone and DMBA-induced multilineage mammary tumors by gene expression profiling

30 October 2018

1 reference

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Impact of ionizing radiation and genetic background on mammary tumorigenesis in p53-deficient mice.

30 October 2018

1 reference

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Inhibition of mammary gland involution is associated with transforming growth factor alpha but not c-myc-induced tumorigenesis in transgenic mice.

30 October 2018

1 reference

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High tumor incidence and activation of the PI3K/AKT pathway in transgenic mice define AIB1 as an oncogene

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053990

Expression of a truncated Int3 gene in developing secretory mammary epithelium specifically retards lobular differentiation resulting in tumorigenesis

30 October 2018

1 reference

12 December 2020

Lactation-induced WAP-SV40 Tag transgene expression in C57BL/6J mice leads to mammary carcinoma

1 reference

12 December 2020

Mammary tumor formation in p53- and BRCA1-deficient mice

1 reference

12 December 2020

A mammary-specific model demonstrates the role of the p53 tumor suppressor gene in tumor development

1 reference

12 December 2020

10.1186/GB-2013-14-11-R125

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24220145%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

6 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24220145%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

24220145

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24220145%20AND%20SRC:MED&resulttype=core&format=json