(Q33745559)

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C1q differentially modulates phagocytosis and cytokine responses during ingestion of apoptotic cells by human monocytes, macrophages, and dendritic cells.

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19864605%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

C1q differentially modulates phagocytosis and cytokine responses during ingestion of apoptotic cells by human monocytes, macrophages, and dendritic cells (English)

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19864605%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

apoptotic process

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1 reference

based on heuristic

inferred from title

1 reference

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Edward L Nelson

3

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19864605%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

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Deborah A Fraser

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19864605%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Amanda K Laust

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19864605%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Andrea J Tenner

4

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Europe PubMed Central

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11 February 2020

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28 October 2009

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Europe PubMed Central

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11 February 2020

Journal of Immunology

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19864605%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

183

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19864605%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

10

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19864605%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

6175-6185

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19864605%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Identification of splenic reservoir monocytes and their deployment to inflammatory sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

21 June 2018

Apoptotic cell-mediated immunoregulation of dendritic cells does not require iC3b opsonization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

21 June 2018

The complement protein properdin binds apoptotic T cells and promotes complement activation and phagocytosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

21 June 2018

Murine low-density lipoprotein receptor-related protein 1 (LRP) is required for phagocytosis of targets bearing LRP ligands but is not required for C1q-triggered enhancement of phagocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

21 June 2018

The consequences of apoptosis in autoimmunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

21 June 2018

Properdin binds to late apoptotic and necrotic cells independently of C3b and regulates alternative pathway complement activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

21 June 2018

Phagocytosis of apoptotic cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

21 June 2018

C1q binds phosphatidylserine and likely acts as a multiligand-bridging molecule in apoptotic cell recognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

21 June 2018

Role of complement and complement regulators in the removal of apoptotic cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

21 June 2018

Immunological consequences of apoptotic cell phagocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

21 June 2018

Generation of inhibitory NFkappaB complexes and phosphorylated cAMP response element-binding protein correlates with the anti-inflammatory activity of complement protein C1q in human monocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

21 June 2018

Dendritic cell and macrophage subsets in the handling of dying cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

21 June 2018

Complement proteins C1q and MBL are pattern recognition molecules that signal immediate and long-term protective immune functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

21 June 2018

Mannose-binding lectin-deficient mice display defective apoptotic cell clearance but no autoimmune phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

21 June 2018

The interface between innate and adaptive immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

21 June 2018

Spontaneous autoimmunity in 129 and C57BL/6 mice-implications for autoimmunity described in gene-targeted mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

21 June 2018

Essential contribution of monocyte chemoattractant protein-1/C-C chemokine ligand-2 to resolution and repair processes in acute bacterial pneumonia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

21 June 2018

Opsonization of apoptotic cells by autologous iC3b facilitates clearance by immature dendritic cells, down-regulates DR and CD86, and up-regulates CC chemokine receptor 7.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

21 June 2018

A blast from the past: clearance of apoptotic cells regulates immune responses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

21 June 2018

Role of surfactant proteins A, D, and C1q in the clearance of apoptotic cells in vivo and in vitro: calreticulin and CD91 as a common collectin receptor complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

21 June 2018

C1q and mannose binding lectin engagement of cell surface calreticulin and CD91 initiates macropinocytosis and uptake of apoptotic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

21 June 2018

Complement. Second of two parts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

21 June 2018

Complement. First of two parts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

21 June 2018

A hierarchical role for classical pathway complement proteins in the clearance of apoptotic cells in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

21 June 2018

CD14-dependent clearance of apoptotic cells: relevance to the immune system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

21 June 2018

Th1 (IL-2, interferon-gamma (IFN-gamma)) and Th2 (IL-10, IL-4) cytokine production by peripheral blood mononuclear cells (PBMC) from patients with systemic lupus erythematosus (SLE).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

21 June 2018

Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

21 June 2018

Monocyte chemoattractant protein-1 is sufficient for the chemotaxis of monocytes and lymphocytes in transgenic mice but requires an additional stimulus for inflammatory activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

21 June 2018

Human recombinant monocyte chemotactic protein and other C-C chemokines bind and induce directional migration of dendritic cells in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

21 June 2018

Monocyte chemoattractant protein 1 acts as a T-lymphocyte chemoattractant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

21 June 2018

Follicular dendritic cells, interdigitating cells, and cells of the monocyte-macrophage lineage are the C1q-producing sources in the spleen. Identification of specific cell types by in situ hybridization and immunohistochemical analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

21 June 2018

Isolation and characterization of C1q, a subcomponent of the first component of complement, from human and rabbit sera

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

21 June 2018

Complement subcomponent C1q secreted by cultured human monocytes has subunit structure identical with that of serum C1q.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

21 June 2018

C1q acts synergistically with phorbol dibutyrate to activate CR1-mediated phagocytosis by human mononuclear phagocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

21 June 2018

Complement subcomponent C1q stimulates Ig production by human B lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

21 June 2018

Direct demonstration and quantitation of the first complement component in human serum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

21 June 2018

The lectin-like activity of human C1q and its implication in DNA and apoptotic cell recognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

30 October 2018

Apoptotic cells induce dendritic cell-mediated suppression via interferon-gamma-induced IDO.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

30 October 2018

Short communication: differences between macrophages and dendritic cells in the cyclic AMP-dependent regulation of lipopolysaccharide-induced cytokine and chemokine synthesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

30 October 2018

Impaired recognition of apoptotic neutrophils by the C1q/calreticulin and CD91 pathway in systemic lupus erythematosus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

30 October 2018

C1q and MBL, components of the innate immune system, influence monocyte cytokine expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

30 October 2018

Involvement of phosphatidylserine, alphavbeta3, CD14, CD36, and complement C1q in the phagocytosis of primary necrotic lymphocytes by macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

30 October 2018

Complement C1q regulates LPS-induced cytokine production in bone marrow-derived dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

30 October 2018

Murine glomerular mesangial cell uptake of apoptotic cells is inefficient and involves serum-mediated but complement-independent mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

30 October 2018

Identification of a site on mannan-binding lectin critical for enhancement of phagocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

30 October 2018

Cycling of human dendritic cell effector phenotypes in response to TNF-alpha: modification of the current 'maturation' paradigm and implications for in vivo immunoregulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

30 October 2018

Differential regulation of chemokine receptors during dendritic cell maturation: a model for their trafficking properties.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

30 October 2018

Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843563

30 October 2018

Kinetics of dendritic cell activation: impact on priming of TH1, TH2 and nonpolarized T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19864605

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reconstitution of the Complement Function in C1q-Deficient (C1qa-/-) Mice with Wild-Type Bone Marrow Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19864605

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct binding of C1q to apoptotic cells and cell blebs induces complement activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19864605

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Maturation-dependent expression of C1q binding proteins on the cell surface of human monocyte-derived dendritic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19864605

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dendritic cells in the arterial wall express C1q: potential significance in atherogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19864605

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Maturation of dendritic cells abrogates C1q production in vivo and in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/19864605

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Opsonization with C1q and mannose-binding lectin targets apoptotic cells to dendritic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19864605

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and radiolabeling of human C1q

1 reference

https://pubmed.ncbi.nlm.nih.gov/19864605

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of C1 by monoclonal antibodies directed against C1q

1 reference

https://pubmed.ncbi.nlm.nih.gov/19864605

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of C1q receptor expression on human phagocytic cells: effects of PDBu and fMLP

1 reference

https://pubmed.ncbi.nlm.nih.gov/19864605

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

C1q binds directly and specifically to surface blebs of apoptotic human keratinocytes: complement deficiency and systemic lupus erythematosus revisited

1 reference

https://pubmed.ncbi.nlm.nih.gov/19864605

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunosuppressive effects of apoptotic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19864605

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of IL-10 in exhaustion of myeloid dendritic cells and rescue by CD40 stimulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19864605

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of TH2 polarization by the chemokine monocyte chemoattractant protein-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/19864605

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immune modulation of human dendritic cells by complement

1 reference

https://pubmed.ncbi.nlm.nih.gov/19864605

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The globular heads of C1q specifically recognize surface blebs of apoptotic vascular endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19864605

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4049/JIMMUNOL.0902232

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19864605%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19864605%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19864605%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

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