(Q33747433)

29 July 2017

1 reference

title

Neuroprotection in acute ischaemic stroke. II: Clinical potential (English)

1 reference

29 July 2017

M Davis

1

1 reference

PubMed ID

10512595

29 July 2017

D Barer

series ordinal

2

1 reference

29 July 2017

1 January 1999

1 reference

29 July 2017

1 reference

29 July 2017

4

1 reference

29 July 2017

3

1 reference

29 July 2017

149-163

1 reference

Why do all drugs work in animals but none in stroke patients? 1. Drugs promoting cerebral blood flow

29 July 2017

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Why do all drugs work in animals but none in stroke patients? 2. Neuroprotective therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Medical treatment of acute ischaemic stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Neuronal necrosis after middle cerebral artery occlusion in Wistar rats progresses at different time intervals in the caudoputamen and the cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Evaluation of critically perfused area in acute ischemic stroke for therapeutic reperfusion: a clinical PET study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

PET imaging of cerebral perfusion and oxygen consumption in acute ischaemic stroke: relation to outcome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

'Spectacular shrinking deficit': rapid recovery from a major hemispheric syndrome by migration of an embolus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Prolonged persistence of substantial volumes of potentially viable brain tissue after stroke: a correlative PET-CT study with voxel-based data analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

A model to predict the histopathology of human stroke using diffusion and T2-weighted magnetic resonance imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Clinical outcome in ischemic stroke predicted by early diffusion-weighted and perfusion magnetic resonance imaging: a preliminary analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Early detection of regional cerebral ischemia in cats: comparison of diffusion- and T2-weighted MRI and spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Early detection of irreversibly damaged ischemic tissue by flumazenil positron emission tomography in cats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Permanent cortical damage detected by flumazenil positron emission tomography in acute stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Monitoring by PET of macrophage accumulation in brain after ischaemic stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Massive persistent release of excitatory amino acids following human occlusive stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Clinical and instrumental evaluation of patients with ischemic stroke within the first six hours.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Spontaneous neurological recovery after stroke and the fate of the ischemic penumbra.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Prognostic value of reperfusion during first 48 hours of ischaemic stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Spontaneous middle cerebral artery reperfusion in ischemic stroke. A follow-up study with transcranial Doppler

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Deteriorating ischemic stroke: risk factors and prognosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

21 January 2018

Cerebral autoregulation

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Autoregulation of cerebral blood flow in experimental focal brain ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Should hypertension be treated after acute stroke? A randomized controlled trial using single photon emission computed tomography.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Treating hypertension after stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Is hyperglycaemia an independent predictor of poor outcome after acute stroke? Results of a long-term follow up study

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Body temperature in acute stroke: relation to stroke severity, infarct size, mortality, and outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Do stroke units save lives?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Differential regional vulnerability in transient focal cerebral ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Neurological deficit and cerebral infarction after temporary middle cerebral artery occlusion in unanesthetized cats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Penumbral tissues salvaged by reperfusion following middle cerebral artery occlusion in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Brain edema during ischemia and after restoration of blood flow. Measurement of water, sodium, potassium content and plasma protein permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Oxygen-derived free radicals in postischemic tissue injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

George E. Brown memorial lecture. Oxygen radicals in cerebral vascular injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Reperfusion-induced injury to the blood-brain barrier after middle cerebral artery occlusion in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Thrombolysis in acute ischemic stroke: does it work?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

A randomized trial comparing ticlopidine hydrochloride with aspirin for the prevention of stroke in high-risk patients. Ticlopidine Aspirin Stroke Study Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE). CAPRIE Steering Committee

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

European Stroke Prevention Study. 2. Dipyridamole and acetylsalicylic acid in the secondary prevention of stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Antithrombotic therapy in acute ischaemic stroke: an overview of the completed randomised trials.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Computed tomographic-angiographic findings within the first five hours of cerebral infarction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

A pilot study of urokinase therapy in cerebral infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Thrombolytic therapy in cerebrovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Thrombolytic therapy in cerebrovascular disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke. The European Cooperative Acute Stroke Study (ECASS)

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Tissue plasminogen activator for acute ischemic stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Biology and therapeutic potential of prostacyclin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

The effect of intracarotid aminophylline infusion on the cerebral circulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

The mechanism of action of aminophylline upon cerebral vascular disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Controlled trial of intravenous aminophylline in acute cerebral infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Beneficial effects of induced hypertension on experimental stroke in awake monkeys.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Phenylephrine-induced hypertension reduces ischemia following middle cerebral artery occlusion in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Effect of haematocrit on cerebral blood-flow in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Custom-tailored hemodilution with albumin and crystalloids in acute ischemic stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

HbXL99 alpha: a hemoglobin derivative that is cross-linked between the alpha subunits is useful as a blood substitute

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Diaspirin cross-linked hemoglobin improves neurological outcome following reversible but not irreversible CNS ischemia in rabbits

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

RENAL EFFECTS OF HEMOGLOBIN INFUSIONS IN DOGS IN HEMORRHAGIC SHOCK

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

ORAL GLYCEROL FOR THE REDUCTION OF INTRACRANIAL PRESSURE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Effect of intravenous infusion of glycerol on hemispheric blood flow and metabolism in patients with acute cerebral infarction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Spontaneous cerebral hypothermia diminishes focal infarction in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Reduction by delayed hypothermia of cerebral infarction following middle cerebral artery occlusion in the rat: a time-course study

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Cerebral protective, metabolic, and vascular effects of phenytoin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Pentobarbital protection from cerebral infarction without suppression of edema.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Effect of oral nimodipine on cerebral infarction and outcome after subarachnoid haemorrhage: British aneurysm nimodipine trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Elevation of the Extracellular Concentrations of Glutamate and Aspartate in Rat Hippocampus During Transient Cerebral Ischemia Monitored by Intracerebral Microdialysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Strategies for neuroprotection with glutamate antagonists. Extrapolating from evidence taken from the first stroke and head injury studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Reduction of infarct volume by magnesium after middle cerebral artery occlusion in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

A randomized, double-blind, placebo-controlled pilot trial of intravenous magnesium sulfate in acute stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Clinical experience with excitatory amino acid antagonist drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

BW619C89, a glutamate release inhibitor, protects against focal cerebral ischemic damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Postischemic blockade of AMPA but not NMDA receptors mitigates neuronal damage in the rat brain following transient severe cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Delayed treatment with AMPA, but not NMDA, antagonists reduces neocortical infarction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

AMPA receptor antagonists and local cerebral glucose utilization in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Expression of human nitric oxide synthase isozymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

NO synthase isozymes have distinct substrate binding sites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Nitric oxide synthase in models of focal ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Bright and dark sides of nitric oxide in ischemic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

L-arginine infusion promotes nitric oxide-dependent vasodilation, increases regional cerebral blood flow, and reduces infarction volume in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Nitric oxide donors increase blood flow and reduce brain damage in focal ischemia: evidence that nitric oxide is beneficial in the early stages of cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Reduction of focal cerebral ischemic damage by delayed treatment with nitric oxide donors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Inducible nitric oxide synthase gene expression in vascular cells after transient focal cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Selective pharmacological inhibition of distinct nitric oxide synthase isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Aminoguanidine ameliorates and L-arginine worsens brain damage from intraluminal middle cerebral artery occlusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Pharmacological reduction of electrophysiological diaschisis after photothrombotic ischemia in rat neocortex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Lubeluzole blocks increases in extracellular glutamate and taurine in the peri-infarct zone in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Lubeluzole treatment of acute ischemic stroke. The US and Canadian Lubeluzole Ischemic Stroke Study Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Treatment of acute ischemic stroke with piracetam. Members of the Piracetam in Acute Stroke Study (PASS) Group.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Pentoxifylline (oxpentifylline). A review of its therapeutic efficacy in the management of peripheral vascular and cerebrovascular disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Pentoxifylline in cerebrovascular dementia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Pentoxifylline in acute nonhemorrhagic stroke. A randomized, placebo-controlled double-blind trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

The importance of the Helsingborg declaration on stroke management in Europe

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Safety study of tirilazad mesylate in patients with acute ischemic stroke (STIPAS).

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Ebselen in acute ischemic stroke: a placebo-controlled, double-blind clinical trial. Ebselen Study Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Carboxyfullerenes as neuroprotective agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Rapid suppression of free radical formation by nerve growth factor involves the mitogen-activated protein kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

A randomized dose-response trial of citicoline in acute ischemic stroke patients. Citicoline Stroke Study Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Early intrathecal production of interleukin-6 predicts the size of brain lesion in stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Endothelial ICAM-1 expression associated with inflammatory cell response in human ischemic stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Cytokines and adhesion molecules in stroke and related diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Intrathecal release of pro- and anti-inflammatory cytokines during stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Tumor necrosis factor-alpha. A mediator of focal ischemic brain injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

New therapeutic possibility of blocking cytokine-induced neutrophil chemoattractant on transient ischemic brain damage in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Circulating antibody against tumor necrosis factor-alpha protects rat brain from reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Antibodies against adhesion molecules reduce apoptosis after transient middle cerebral artery occlusion in rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Interleukin-1 receptor and receptor antagonist gene expression after focal stroke in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Protective mechanisms of adenosine in neurons and glial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Considerations in the design of clinical trials of neuroprotective therapy in acute stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

SERIAL OBSERVATIONS ON THE PATHOPHYSIOLOGY OF ACUTE STROKE

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

Streptokinase in acute ischaemic stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1358836X9900400306

10.1177/1358836X9900400306

21 January 2018

Identifiers

DOI

1 reference

29 July 2017

1 reference

PubMed ID

10512595