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The inflammasomes: mechanisms of activation and function
scientific article
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
20060699
retrieved
29 July 2017
review article
1 reference
stated in
Europe PubMed Central
title
The inflammasomes: mechanisms of activation and function
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
20060699
retrieved
29 July 2017
main subject
inflammasome complex
1 reference
based on heuristic
inferred from title
author name string
Eicke Latz
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
20060699
retrieved
29 July 2017
publication date
8 January 2010
1 reference
stated in
Europe PubMed Central
PubMed ID
20060699
retrieved
29 July 2017
published in
Current Opinion in Immunology
1 reference
stated in
Europe PubMed Central
PubMed ID
20060699
retrieved
29 July 2017
volume
22
1 reference
stated in
Europe PubMed Central
PubMed ID
20060699
retrieved
29 July 2017
page(s)
28-33
1 reference
stated in
Europe PubMed Central
PubMed ID
20060699
retrieved
29 July 2017
issue
1
1 reference
stated in
Europe PubMed Central
PubMed ID
20060699
retrieved
29 July 2017
cites work
Pure Hemozoin is inflammatory in vivo and activates the NALP3 inflammasome via release of uric acid
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844336
retrieved
28 July 2018
Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844336
retrieved
28 July 2018
Malarial hemozoin is a Nalp3 inflammasome activating danger signal
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844336
retrieved
28 July 2018
Cutting edge: Necrosis activates the NLRP3 inflammasome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844336
retrieved
28 July 2018
Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844336
retrieved
28 July 2018
Cutting edge: TNF-alpha mediates sensitization to ATP and silica via the NLRP3 inflammasome in the absence of microbial stimulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844336
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28 July 2018
An essential role for the NLRP3 inflammasome in host defense against the human fungal pathogen Candida albicans
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844336
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28 July 2018
Neisseria gonorrhoeae activates the proteinase cathepsin B to mediate the signaling activities of the NLRP3 and ASC-containing inflammasome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844336
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28 July 2018
Horror autoinflammaticus: the molecular pathophysiology of autoinflammatory disease (*)
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844336
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28 July 2018
Immunological and inflammatory functions of the interleukin-1 family
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844336
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28 July 2018
The inflammasomes: guardians of the body
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844336
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28 July 2018
An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844336
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28 July 2018
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844336
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28 July 2018
HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844336
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28 July 2018
Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844336
retrieved
28 July 2018
NLRC4/IPAF: a CARD carrying member of the NLR family
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844336
retrieved
28 July 2018
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844336
retrieved
28 July 2018
The NALP3 inflammasome is involved in the innate immune response to amyloid-beta
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844336
retrieved
28 July 2018
The Nalp3 inflammasome is essential for the development of silicosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844336
retrieved
28 July 2018
Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844336
retrieved
28 July 2018
The NLR gene family: a standard nomenclature
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844336
retrieved
28 July 2018
Active caspase-1 is a regulator of unconventional protein secretion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844336
retrieved
28 July 2018
The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844336
retrieved
28 July 2018
Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844336
retrieved
28 July 2018
Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844336
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28 July 2018
Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844336
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28 July 2018
Host-microbe interactions: shaping the evolution of the plant immune response
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844336
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28 July 2018
Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844336
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28 July 2018
Cryopyrin activates the inflammasome in response to toxins and ATP
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844336
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28 July 2018
Gout-associated uric acid crystals activate the NALP3 inflammasome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844336
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28 July 2018
Cutting edge: CIAS1/cryopyrin/PYPAF1/NALP3/CATERPILLER 1.1 is an inducible inflammatory mediator with NF-kappa B suppressive properties
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844336
retrieved
28 July 2018
A Pseudomonas syringae type III effector suppresses cell wall-based extracellular defense in susceptible Arabidopsis plants
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844336
retrieved
28 July 2018
Toll-like receptors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844336
retrieved
28 July 2018
The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844336
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28 July 2018
Plant pathogens and integrated defence responses to infection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844336
retrieved
28 July 2018
A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844336
retrieved
28 July 2018
Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844336
retrieved
30 October 2018
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844336
retrieved
30 October 2018
Cryopyrin/NALP3 binds ATP/dATP, is an ATPase, and requires ATP binding to mediate inflammatory signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844336
retrieved
30 October 2018
Superoxide dismutase 1 regulates caspase-1 and endotoxic shock
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20060699
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.COI.2009.12.004
1 reference
stated in
Europe PubMed Central
PubMed ID
20060699
retrieved
29 July 2017
PMCID
2844336
1 reference
stated in
Europe PubMed Central
PubMed ID
20060699
retrieved
29 July 2017
PubMed ID
20060699
1 reference
stated in
Europe PubMed Central
PubMed ID
20060699
retrieved
29 July 2017
ResearchGate publication ID
40898448
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