(Q33750221)

29 July 2017

title

High ALDH activity identifies chemotherapy-resistant Ewing's sarcoma stem cells that retain sensitivity to EWS-FLI1 inhibition (English)

1 reference

29 July 2017

1 reference

Ola Awad

1

1 reference

29 July 2017

Jason T Yustein

2

1 reference

29 July 2017

Preeti Shah

3

1 reference

29 July 2017

Naheed Gul

4

1 reference

29 July 2017

Varalakshmi Katuri

5

1 reference

29 July 2017

Alison O'Neill

6

1 reference

29 July 2017

Yali Kong

7

1 reference

29 July 2017

Milton L Brown

8

1 reference

29 July 2017

Jeffrey A Toretsky

9

1 reference

29 July 2017

David M Loeb

10

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29 July 2017

language of work or name

English

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publication date

11 November 2010

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29 July 2017

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29 July 2017

volume

5

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29 July 2017

issue

11

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29 July 2017

page(s)

e13943

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Creative Commons Attribution 4.0 International

29 July 2017

copyright license

start time

11 November 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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CD133 expression in chemo-resistant Ewing sarcoma cells

21 June 2018

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EWS/FLI1 oncogene activates caspase 3 transcription and triggers apoptosis in vivo

21 June 2018

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A small molecule blocking oncogenic protein EWS-FLI1 interaction with RNA helicase A inhibits growth of Ewing's sarcoma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978678

Resistance to cytotoxic chemotherapy-induced apoptosis in side population cells of human oral squamous cell carcinoma cell line Ho-1-N-1.

21 June 2018

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Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis

21 June 2018

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Aldehyde dehydrogenase 1 is a tumor stem cell-associated marker in lung cancer

21 June 2018

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Identification of cancer stem cells in Ewing's sarcoma

21 June 2018

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Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature

21 June 2018

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GLI1 is a direct transcriptional target of EWS-FLI1 oncoprotein.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978678

EWS-Fli1 up-regulates expression of the Aurora A and Aurora B kinases.

21 June 2018

1 reference

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An orally bioavailable small-molecule inhibitor of Hedgehog signaling inhibits tumor initiation and metastasis in pancreatic cancer.

21 June 2018

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IGF1 is a common target gene of Ewing's sarcoma fusion proteins in mesenchymal progenitor cells.

21 June 2018

1 reference

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Colorectal cancer stem cells are enriched in xenogeneic tumors following chemotherapy

21 June 2018

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ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome

21 June 2018

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Blockade of hedgehog signaling inhibits pancreatic cancer invasion and metastases: a new paradigm for combination therapy in solid cancers

21 June 2018

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Identification and expansion of human colon-cancer-initiating cells

21 June 2018

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Oncoprotein EWS-FLI1 activity is enhanced by RNA helicase A.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978678

Development of Ewing's sarcoma from primary bone marrow-derived mesenchymal progenitor cells

21 June 2018

1 reference

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Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties

21 June 2018

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Tumour stem cells and drug resistance

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978678

A distinct "side population" of cells with high drug efflux capacity in human tumor cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978678

Role of human aldehyde dehydrogenases in endobiotic and xenobiotic metabolism.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978678

Targeting the multidrug resistance-1 transporter in AML: molecular regulation and therapeutic strategies

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978678

Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978678

Identification of a cancer stem cell in human brain tumors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978678

Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978678

Prospective identification of tumorigenic breast cancer cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978678

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978678

EWS/FLI-1 antagonists induce growth inhibition of Ewing tumor cells in vitro

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978678

EWS-Fli1 antisense oligodeoxynucleotide inhibits proliferation of human Ewing's sarcoma and primitive neuroectodermal tumor cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978678

The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978678

Loss of tumorigenicity of Ewing's sarcoma cells expressing antisense RNA to EWS-fusion transcripts

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978678

In vitro chemosensitivity of two Ewing's sarcoma cell lines: implication for autologous bone marrow transplantation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978678

Addition of ifosfamide and etoposide to standard chemotherapy for Ewing's sarcoma and primitive neuroectodermal tumor of bone

21 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013943

Primary disseminated multifocal Ewing sarcoma: results of the Euro-EWING 99 trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013943

Treatment of metastatic Ewing sarcoma/primitive neuroectodermal tumor of bone: evaluation of increasing the dose intensity of chemotherapy--a report from the Children's Oncology Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013943

Oct4 and its pseudogenes confuse stem cell research.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013943

Detoxification of cyclophosphamide by human aldehyde dehydrogenase isozymes

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21085683

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0013943

1 reference

29 July 2017

0 references

1 reference

29 July 2017

1 reference