(Q33754400)

29 July 2017

title

Designing safer chemicals: predicting the rates of metabolism of halogenated alkanes (English)

1 reference

29 July 2017

H Yin

1

1 reference

29 July 2017

M W Anders

2

1 reference

29 July 2017

K R Korzekwa

3

1 reference

29 July 2017

L Higgins

4

1 reference

29 July 2017

K E Thummel

5

1 reference

29 July 2017

E D Kharasch

6

1 reference

29 July 2017

J P Jones

7

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29 July 2017

language of work or name

English

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publication date

1 November 1995

1 reference

Proceedings of the National Academy of Sciences of the United States of America

29 July 2017

published in

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29 July 2017

volume

92

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29 July 2017

issue

24

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29 July 2017

page(s)

11076-11080

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Predicting the cytochrome P450 mediated metabolism of xenobiotics.

29 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40574

Identification of cytochrome P450 2E1 as the predominant enzyme catalyzing human liver microsomal defluorination of sevoflurane, isoflurane, and methoxyflurane.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40574

Gas-uptake pharmacokinetics of 2,2-dichloro-1,1,1-trifluoroethane (HCFC-123).

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40574

Human kidney methoxyflurane and sevoflurane metabolism. Intrarenal fluoride production as a possible mechanism of methoxyflurane nephrotoxicity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40574

Renal Effects and Metabolism of Isoflurane in Man

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40574

Methoxyflurane nephrotoxicity. A study of dose response in man

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40574

Intrinsic isotope effects suggest that the reaction coordinate symmetry for the cytochrome P-450 catalyzed hydroxylation of octane is isozyme independent

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40574

Mechanisms of cytochrome P-450 catalysis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40574

Tissue acylation by the chlorofluorocarbon substitute 2,2-dichloro-1,1,1-trifluoroethane

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40574

Oxidative defluorination of 1,1,1,2-tetrafluoroethane by rat liver microsomes.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40574

Oxidation of toxic and carcinogenic chemicals by human cytochrome P-450 enzymes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40574

Fluoride metabolites after prolonged exposure of volunteers and patients to desflurane.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40574

Metabolism and toxicity of hydrochlorofluorocarbons: current knowledge and needs for the future

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40574

Comparison of Induction, Maintenance, and Recovery Characteristics of Sevoflurane-N2O and Propofol-Sevoflurane-N2O With Propofol-Isoflurane-N2O Anesthesia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40574

Plasma inorganic fluoride with sevoflurane anesthesia: correlation with indices of hepatic and renal function.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40574

Metabolism in vivo and in vitro of the refrigerant substitute 1,1,1,2-tetrafluoro-2-chloroethane

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40574

Expression of mammalian cytochrome P450 using vaccinia virus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40574

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40574

Isoniazid-induced enflurane defluorination in humans.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40574

Oxidation of 1,1,1,2-tetrafluoroethane in rat liver microsomes is catalyzed primarily by cytochrome P-450IIE1

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40574

Pentahaloethane-based chlorofluorocarbon substitutes and halothane: correlation of in vivo hepatic protein trifluoroacetylation and urinary trifluoroacetic acid excretion with calculated enthalpies of activation

30 October 2018

1 reference

12 December 2020

Modeling cyanide release from nitriles: prediction of cytochrome P450 mediated acute nitrile toxicity

1 reference

12 December 2020

The CFC-Ozone Issue: Progress on the Development of Alternatives to CFCs

1 reference

12 December 2020

EPA campaigns for safer chemicals

1 reference

12 December 2020

Metabolism of the hydrochlorofluorocarbon 1,2-dichloro-1,1-difluoroethane

1 reference

12 December 2020

Induction by pyridine of cytochrome P450IIE1 and xenobiotic metabolism in rat lung and liver

1 reference

12 December 2020

Disposition of azole antifungal agents. II. Hepatic binding and clearance of dichlorophenyl-bis-triazolylpropanol (DTP) in the rat

1 reference

12 December 2020

Studies on the mechanism of acute toxicity of nitriles in mice

1 reference

12 December 2020

Determination of sulphonamides by electron-capture gas chromatography preparation and properties of perfluoroacyl and pentafluorobenzyl derivatives

1 reference

12 December 2020

Mechanistic studies of uridine diphosphate glucuronosyltransferase

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.92.24.11076

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29 July 2017

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29 July 2017

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