(Q33756668)

English

T-bet down-modulation in tolerized Th1 effector CD4 cells confers a TCR-distal signaling defect that selectively impairs IFN-gamma expression

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scholarly article

1 reference

Europe PubMed Central

29 July 2017

T-bet down-modulation in tolerized Th1 effector CD4 cells confers a TCR-distal signaling defect that selectively impairs IFN-gamma expression (English)

1 reference

Europe PubMed Central

29 July 2017

author name string

Meixiao Long

1

1 reference

Europe PubMed Central

29 July 2017

Aaron M Slaiby

2

1 reference

Europe PubMed Central

29 July 2017

Adam T Hagymasi

3

1 reference

Europe PubMed Central

29 July 2017

Marianne A Mihalyo

4

1 reference

Europe PubMed Central

29 July 2017

Alexander C Lichtler

5

1 reference

Europe PubMed Central

29 July 2017

Steven L Reiner

6

1 reference

Europe PubMed Central

29 July 2017

Adam J Adler

7

1 reference

Europe PubMed Central

29 July 2017

language of work or name

0 references

publication date

1 January 2006

1 reference

Europe PubMed Central

29 July 2017

Journal of Immunology

1 reference

Europe PubMed Central

29 July 2017

176

1 reference

Europe PubMed Central

29 July 2017

2

1 reference

Europe PubMed Central

29 July 2017

1036-1045

1 reference

Europe PubMed Central

29 July 2017

Peripheral Tolerization of Effector and Memory T Cells: Implications for Autoimmunity and Tumor-Immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846362

21 June 2018

T-bet antagonizes mSin3a recruitment and transactivates a fully methylated IFN-gamma promoter via a conserved T-box half-site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846362

21 June 2018

Silencing T-bet defines a critical role in the differentiation of autoreactive T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846362

21 June 2018

Identification of a novel type 1 diabetes susceptibility gene, T-bet

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846362

21 June 2018

In vivo cyclophosphamide and IL-2 treatment impedes self-antigen-induced effector CD4 cell tolerization: implications for adoptive immunotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846362

21 June 2018

Effector CD4 cell tolerization is mediated through functional inactivation and involves preferential impairment of TNF-alpha and IFN-gamma expression potentials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846362

21 June 2018

TNF plays an essential role in tumor regression after adoptive transfer of perforin/IFN-gamma double knockout effector T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846362

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846362

21 June 2018

Effector CD4 cells are tolerized upon exposure to parenchymal self-antigen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846362

21 June 2018

Memory CD8(+) T cells undergo peripheral tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846362

21 June 2018

Cutting edge: changes in histone acetylation at the IL-4 and IFN-gamma loci accompany Th1/Th2 differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846362

21 June 2018

Transcriptional mechanisms underlying lymphocyte tolerance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846362

21 June 2018

Hlx is induced by and genetically interacts with T-bet to promote heritable T(H)1 gene induction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846362

21 June 2018

The roles of IFN gamma in protection against tumor development and cancer immunoediting

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846362

21 June 2018

Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846362

21 June 2018

Certified professionals: CD4(+)CD25(+) suppressor T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846362

21 June 2018

Regulatory T cells: key controllers of immunologic self-tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846362

21 June 2018

A novel transcription factor, T-bet, directs Th1 lineage commitment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846362

21 June 2018

The central role of CD4(+) T cells in the antitumor immune response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846362

21 June 2018

Molecular mimicry and immune-mediated diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846362

21 June 2018

Helper T cell differentiation is controlled by the cell cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846362

21 June 2018

CD4+ T cell tolerance to parenchymal self-antigens requires presentation by bone marrow-derived antigen-presenting cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846362

21 June 2018

Interferon-gamma is essential for destruction of beta cells and development of insulin-dependent diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846362

21 June 2018

Conditions that induce tolerance in mature CD4+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846362

21 June 2018

A pathogenetic role for TNF alpha in the syndrome of cachexia, arthritis, and autoimmunity resulting from tristetraprolin (TTP) deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846362

21 June 2018

Effect of tumor necrosis factor alpha on insulin-dependent diabetes mellitus in NOD mice. I. The early development of autoimmunity and the diabetogenic process

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846362

21 June 2018

Thymic selection of CD8+ single positive cells with a class II major histocompatibility complex-restricted receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846362

21 June 2018

Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846362

21 June 2018

Early signaling defects in human T cells anergized by T cell presentation of autoantigen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846362

21 June 2018

A signal through OX40 (CD134) allows anergic, autoreactive T cells to acquire effector cell functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846362

30 October 2018

T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846362

30 October 2018

Role of T-bet in commitment of TH1 cells before IL-12-dependent selection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846362

30 October 2018

Virus-induced autoimmune diabetes: most beta-cells die through inflammatory cytokines and not perforin from autoreactive (anti-viral) cytotoxic T-lymphocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846362

30 October 2018

CD4+ T cell--mediated tumor rejection involves inhibition of angiogenesis that is dependent on IFN gamma receptor expression by nonhematopoietic cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846362

30 October 2018

Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846362

30 October 2018

CD4 cell priming and tolerization are differentially programmed by APCs upon initial engagement

1 reference

https://pubmed.ncbi.nlm.nih.gov/16393991

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blocked Signal Transduction to the ERK and JNK Protein Kinases in Anergic CD4+ T Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16393991

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peripheral deletion of mature CD8+ antigen-specific T cells after in vivo exposure to male antigen

1 reference

https://pubmed.ncbi.nlm.nih.gov/16393991

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of interferon-γ production in Th1 CD4+ T cells: evidence for two distinct pathways for promoter activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16393991

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peripheral tolerance through clonal deletion of mature CD4-CD8+ T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16393991

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peripheral clonal elimination of functional T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16393991

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunotherapy of melanoma: a dichotomy in the requirement for IFN-gamma in vaccine-induced antitumor immunity versus adoptive immunotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/16393991

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T-bet is a STAT1-induced regulator of IL-12R expression in naïve CD4+ T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16393991

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of chromatin structure regulates cytokine gene expression during T cell differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16393991

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antigen-induced unresponsiveness results in altered T cell signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/16393991

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Positive and negative thymocyte selection induced by different concentrations of a single peptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/16393991

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo CD4+ T cell tolerance induction versus priming is independent of the rate and number of cell divisions

1 reference

https://pubmed.ncbi.nlm.nih.gov/16393991

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T-cell apoptosis detected in situ during positive and negative selection in the thymus

1 reference

https://pubmed.ncbi.nlm.nih.gov/16393991

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anergic Th1 cells express altered levels of the protein tyrosine kinases p56lck and p59fyn

1 reference

https://pubmed.ncbi.nlm.nih.gov/16393991

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of cooperative monomeric Brachyury sites conferring T-bet responsiveness to the proximal IFN-gamma promoter

1 reference

https://pubmed.ncbi.nlm.nih.gov/16393991

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T cell tolerance by clonal elimination in the thymus

1 reference

https://pubmed.ncbi.nlm.nih.gov/16393991

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blocked Ras activation in anergic CD4+ T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16393991

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4049/JIMMUNOL.176.2.1036

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

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