(Q33762505)

29 July 2017

3 references

20 June 2019

19 September 2019

22 August 2022

Benchmarking B-cell epitope prediction for the design of peptide-based vaccines: problems and prospects (English)

1 reference

biomedical investigative technique

29 July 2017

main subject

1 reference

19 September 2019

1 reference

Salvador Eugenio C Caoili

series ordinal

1

1 reference

29 July 2017

publication date

30 March 2010

4 references

Journal of Biomedicine and Biotechnology

29 July 2017

20 June 2019

19 September 2019

22 August 2022

4 references

29 July 2017

20 June 2019

19 September 2019

22 August 2022

2010

1 reference

29 July 2017

page(s)

910524

1 reference

Creative Commons Attribution 3.0 Unported

29 July 2017

copyright license

start time

1 January 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

cites work

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Antibody epitope mapping using SPOT peptide arrays

22 June 2018

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Interplay of alpha-synuclein binding and conformational switching probed by single-molecule fluorescence.

22 June 2018

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Structure-activity relationships in peptide-antibody complexes: implications for epitope prediction and development of synthetic peptide vaccines.

22 June 2018

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Reconciling binding mechanisms of intrinsically disordered proteins.

22 June 2018

1 reference

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Linking folding and binding

22 June 2018

1 reference

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Advances in automatic, manual and microwave-assisted solid-phase peptide synthesis

22 June 2018

1 reference

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The unfoldomics decade: an update on intrinsically disordered proteins.

22 June 2018

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The curation guidelines of the immune epitope database and analysis resource

22 June 2018

1 reference

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The twilight zone between protein order and disorder

22 June 2018

1 reference

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B cell epitope mapping using synthetic peptides

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Searching the NCBI databases using Entrez

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

HIV-1 neutralization: mechanisms and relevance to vaccine design

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Genomics and vaccine development

22 June 2018

1 reference

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Neutralization of animal virus infectivity by antibody

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

More than one reason to rethink the use of peptides in vaccine design

22 June 2018

1 reference

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The growing incidence of cancer: role of lifestyle and screening detection (Review).

22 June 2018

1 reference

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Towards a consensus on datasets and evaluation metrics for developing B-cell epitope prediction tools

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Binding of intrinsically disordered proteins is not necessarily accompanied by a structural transition to a folded form

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Intrinsic disorder and functional proteomics

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Current status of short synthetic peptides as vaccines

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Variability in the immunodetection of His-tagged recombinant proteins

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

A structural-energetic basis for B-cell epitope prediction

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Immunoinformatics comes of age

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Curation of complex, context-dependent immunological data

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Improved method for predicting linear B-cell epitopes

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Emerging and re-emerging infectious diseases: influenza as a prototype of the host-pathogen balancing act.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Structure and kinetics of a transient antibody binding intermediate reveal a kinetic discrimination mechanism in antigen recognition

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

CEP: a conformational epitope prediction server.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Natively unfolded proteins

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

22 June 2018

Genome-derived vaccines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Protein folding revisited. A polypeptide chain at the folding ? misfolding ? nonfolding cross-roads: which way to go?

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Reductionism and the search for structure-function relationships in antibody molecules

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Occupancy and mechanism in antibody-mediated neutralization of animal viruses

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Vaccines: predicting the risk of allergy and autoimmunity

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Non-clinical vaccine safety assessment

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Mimotopes of viral antigens and biologically important molecules as candidate vaccines and potential immunotherapeutics

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Coupling of folding and binding for unstructured proteins

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

A model for neutralization of viruses based on antibody coating of the virion surface

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Intrinsically disordered protein

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

The antiviral activity of antibodies in vitro and in vivo.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Antigenic and immunogenic phage displayed mimotopes as substitute antigens: applications and limitations

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Pitfalls of reductionism in the design of peptide-based vaccines

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Peptide mimotopes as candidate vaccines

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Cryptic and exposed invariable regions of VlsE, the variable surface antigen of Borrelia burgdorferi sl.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Structural energetics of protein folding and binding.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Predicting binding energetics from structure: looking beyond DeltaG degrees.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Studies on the topology of the renal type II NaPi-cotransporter

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Development of an antipeptide antibody that binds to the C-terminal region of human CYP1B1.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Structural and functional analysis of SFT, a stimulator of Fe Transport

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

The role of structure in antibody cross-reactivity between peptides and folded proteins

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Synthesis of peptides for use as immunogens

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Cell surface expression of the Alzheimer disease-related presenilin proteins

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

The cluster of basic amino acids in vitronectin contributes to its binding of plasminogen activator inhibitor-1: evidence from thrombin-, elastase- and plasmin-cleaved vitronectins and anti-peptide antibodies

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Production of antisera using peptide conjugates.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

In situ topology of cytochrome b5 in the endoplasmic reticulum membrane.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Antipeptide antibodies confirm the topology of the human norepinephrine transporter

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Mapping of neutralizing epitopes and the receptor binding site of human interleukin 1 beta

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Entropic effects of disulphide bonds on protein stability

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Epitope mapping of a protein using the Geysen (PEPSCAN) procedure

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Predicting antigenic determinants in proteins: looking for unidimensional solutions to a three-dimensional problem?

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Immunogenic structure of the influenza virus hemagglutinin

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Prediction of protein antigenic determinants from amino acid sequences

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Discovery and implications of the immunogenicity of free small synthetic peptides: powerful tools for manipulating the immune system and for production of antibodies and T cells of preselected submolecular specificities

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Characterization of antisera to a synthetic carboxyl-terminal peptide of the glucose transporter protein

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Measuring the accuracy of diagnostic systems

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Synthetic peptides of Shiga toxin B subunit induce antibodies which neutralize its biological activity

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Reaction of staphylococcal alpha-toxin with peptide-induced antibodies.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Antigenic determinants in proteins coincide with surface regions accessible to large probes (antibody domains).

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Point mutation in the cytoplasmic domain of the neutrophil p22-phox cytochrome b subunit is associated with a nonfunctional NADPH oxidase and chronic granulomatous disease

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

8 Predicting location of continuous epitopes in proteins from their primary structures

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Identification of linear B-cell determinants of pertussis toxin associated with the receptor recognition site of the S3 subunit.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Epitopes on protein antigens: misconceptions and realities.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Thermodynamics of structural stability and cooperative folding behavior in proteins

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Benchmarking B cell epitope prediction: underperformance of existing methods

22 June 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F910524

Immunization with peptide-protein conjugates: impact on benchmarking B-cell epitope prediction for vaccine design

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F910524

Flavors of protein disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F910524

Prediction of linear B-cell epitopes

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F910524

An in silico method using an epitope motif database for predicting the location of antigenic determinants on proteins in a structural context.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F910524

Variability in the pKa of histidine side-chains correlates with burial within proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F910524

The evolutionary consequences of plasticity in host-pathogen interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F910524

Aldehyde modification of peptide immunogen enhances protein-reactive antibody response to toxic shock syndrome toxin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F910524

21 January 2018

Conjugation of Haptens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Developing countries face double burden of disease

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847767

Genuine and apparent cross-reaction of polyclonal antibodies to proteins and peptides

30 October 2018

1 reference

12 December 2020

Transition-state theory and secondary forces in antigen--antibody complexes

1 reference

12 December 2020

Analysis of the relationship between immunogenicity and immunity for viral subunit vaccines

1 reference

12 December 2020

Histidine-aromatic interactions in barnase. Elevation of histidine pKa and contribution to protein stability

1 reference

12 December 2020

The protein non-folding problem: amino acid determinants of intrinsic order and disorder

1 reference

12 December 2020

Molecular recognition in the post-reductionist era

1 reference

12 December 2020

Predicting B cell epitope residues with network topology based amino acid indices

1 reference

12 December 2020

Immunoinformatics may lead to a reappraisal of the nature of B cell epitopes and of the feasibility of synthetic peptide vaccines

1 reference

12 December 2020

Monoclonal antibodies distinguish synthetic peptides that differ in one chemical group

1 reference

12 December 2020

Immunochemical studies of human erythropoietin using site-specific anti-peptide antibodies. Identification of a functional domain

1 reference

12 December 2020

Application and limitations of the multiple antigen peptide (MAP) system in the production and evaluation of anti-peptide and anti-protein antibodies

1 reference

12 December 2020

Localization of an immune functional site on staphylococcal enterotoxin A using the synthetic peptide approach

1 reference

12 December 2020

Production of antisera to synthetic peptides

1 reference

12 December 2020

Consequences of dichotomization

1 reference

12 December 2020

Adsorption equilibrium in immunoaffnity chromatography with antibodies to synthetic peptides

1 reference

12 December 2020

High-resolution immunogold localization of AMPA type glutamate receptor subunits at synaptic and non-synaptic sites in rat hippocampus

1 reference

12 December 2020

Characterization of monoclonal antibodies raised against a synthetic peptide capable of inducing a neutralizing response to human rhinovirus type 2

1 reference

12 December 2020

Histidine residues at the N- and C-termini of alpha-helices: perturbed pKas and protein stability

1 reference

12 December 2020

Caveats for the use of surface-adsorbed protein antigen to test the specificity of antibodies

1 reference

12 December 2020

Production and characterization of human renin antibodies with region-oriented synthetic peptides

1 reference

12 December 2020

Biological complexity emerges from the ashes of genetic reductionism

1 reference

12 December 2020

Mechanisms of antibody binding to a protein

1 reference

12 December 2020

B cell responses to a peptide epitope. X. Epitope selection in a primary response is thermodynamically regulated

1 reference

12 December 2020

Synthetic peptides as antigens: pitfalls of conjugation methods

1 reference

12 December 2020

Antibody binding to a peptide but not the whole protein by recognition of the C-terminal carboxy group

1 reference

12 December 2020

Site-directed anti-peptide antibodies define the topography of the beta-adrenergic receptor

1 reference

12 December 2020

Immunization with a peptide having both T cell and conformationally restricted B cell epitopes elicits neutralizing antisera against a snake neurotoxin

1 reference

12 December 2020

Identifiers

DOI

10.1155/2010/910524

1 reference

29 July 2017

1 reference

29 July 2017

1 reference