(Q33762852)

29 July 2017

title

Allosteric switching of agonist/antagonist activity by a single point mutation in the interluekin-1 receptor antagonist, IL-1Ra (English)

1 reference

29 July 2017

1 reference

Kendra L Hailey

1

1 reference

29 July 2017

Dominique T Capraro

series ordinal

2

1 reference

29 July 2017

Sulyman Barkho

series ordinal

3

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29 July 2017

Patricia A Jennings

series ordinal

4

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29 July 2017

publication date

15 March 2013

1 reference

Journal of Molecular Biology

29 July 2017

published in

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29 July 2017

volume

425

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29 July 2017

issue

13

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29 July 2017

page(s)

2382-2392

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describes a project that uses

29 July 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4059520/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Folding circular permutants of IL-1β: route selection driven by functional frustration

22 June 2018

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β-Bulge triggers route-switching on the functional landscape of interleukin-1β.

22 June 2018

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Structural insights into the assembly and activation of IL-1β with its receptors

22 June 2018

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Pro-interleukin (IL)-1beta shares a core region of stability as compared with mature IL-1beta while maintaining a distinctly different configurational landscape: a comparative hydrogen/deuterium exchange mass spectrometry study

22 June 2018

1 reference

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Differential requirement for the activation of the inflammasome for processing and release of IL-1beta in monocytes and macrophages

22 June 2018

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Backtracking on the folding landscape of the beta-trefoil protein interleukin-1beta?

22 June 2018

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22 June 2018

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22 June 2018

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Allosteric signaling of ATP hydrolysis in GroEL-GroES complexes

22 June 2018

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22 June 2018

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22 June 2018

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22 June 2018

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Signaling to NF-kappaB

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The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation

22 June 2018

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Three topologically equivalent core residues affect the transition state ensemble in a protein folding reaction

22 June 2018

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The interleukin-1 receptor/Toll-like receptor superfamily: signal transduction during inflammation and host defense.

22 June 2018

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How native-state topology affects the folding of dihydrofolate reductase and interleukin-1beta

22 June 2018

1 reference

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Evolutionarily conserved pathways of energetic connectivity in protein families

22 June 2018

1 reference

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The type II IL-1 receptor interacts with the IL-1 receptor accessory protein: a novel mechanism of regulation of IL-1 responsiveness

22 June 2018

1 reference

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Interleukin-1 receptor antagonist: role in biology

22 June 2018

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A new cytokine-receptor binding mode revealed by the crystal structure of the IL-1 receptor with an antagonist

22 June 2018

1 reference

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Crystal structure of the type-I interleukin-1 receptor complexed with interleukin-1beta

22 June 2018

1 reference

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Receptor binding and biological activity of IL-1 alpha, IL-1 beta, IL-1 beta analogues and an IL-1 antagonist in A375 human melanoma cells

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059520

Breakdown in the relationship between thermal and thermodynamic stability in an interleukin-1 beta point mutant modified in a surface loop

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059520

Binding of IL-1 alpha, IL-1 beta, and IL-1 receptor antagonist by soluble IL-1 receptors and levels of soluble IL-1 receptors in synovial fluids.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059520

Disulfide Bonds in Protein Folding and Stability

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059520

Interleukin-1 beta secretion. A possible multistep process that is regulated in a cell type-specific manner

22 June 2018

1 reference

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An engineered disulfide bond in dihydrofolate reductase.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059520

Calculation of protein extinction coefficients from amino acid sequence data

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059520

Long-range coupling between separate docking sites in interleukin-1beta

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059520

Intramolecular signaling pathways revealed by modeling anisotropic thermal diffusion

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059520

The native energy landscape for interleukin-1beta. Modulation of the population ensemble through native-state topology

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059520

Mapping receptor binding sites in interleukin (IL)-1 receptor antagonist and IL-1 beta by site-directed mutagenesis. Identification of a single site in IL-1ra and two sites in IL-1 beta.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059520

Allosteric disulfide bonds

30 October 2018

1 reference

12 December 2020

Biophysical characterization of structural properties and folding of interleukin-1 receptor antagonist

1 reference

12 December 2020

The IL-1 receptor/toll-like receptor superfamily: crucial receptors for inflammation and host defense

1 reference

12 December 2020

Secondary structure and topology of interleukin-1 receptor antagonist protein determined by heteronuclear three-dimensional NMR spectroscopy

1 reference

12 December 2020

Kinetics of folding of the all-beta sheet protein interleukin-1 beta

1 reference

12 December 2020

10.1016/J.JMB.2013.03.016

Identifiers

DOI

1 reference

29 July 2017

1 reference

29 July 2017

1 reference