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Advances in vaccine adjuvants
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
10545912
retrieved
29 July 2017
review article
1 reference
stated in
Europe PubMed Central
title
Advances in vaccine adjuvants
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
10545912
retrieved
29 July 2017
main subject
vaccine
1 reference
based on heuristic
inferred from title
author name string
Singh M
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
10545912
retrieved
29 July 2017
O'Hagan D
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
10545912
retrieved
29 July 2017
publication date
1 November 1999
1 reference
stated in
Europe PubMed Central
PubMed ID
10545912
retrieved
29 July 2017
published in
Nature Biotechnology
1 reference
stated in
Europe PubMed Central
PubMed ID
10545912
retrieved
29 July 2017
volume
17
1 reference
stated in
Europe PubMed Central
PubMed ID
10545912
retrieved
29 July 2017
issue
11
1 reference
stated in
Europe PubMed Central
PubMed ID
10545912
retrieved
29 July 2017
page(s)
1075-1081
1 reference
stated in
Europe PubMed Central
PubMed ID
10545912
retrieved
29 July 2017
exact match
https://scigraph.springernature.com/pub.10.1038/15058
0 references
cites work
Poly(lactide-co-glycolide) microparticles for the development of single-dose controlled-release vaccines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rational approaches to reduce adverse reactions in man to vaccines containing tetanus and diphtheria toxoids
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2F15058
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7 January 2021
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Two types of mouse helper T cell clone. III. Further differences in lymphokine synthesis between Th1 and Th2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
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7 January 2021
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The role of IL-10 in crossregulation of TH1 and TH2 responses
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
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7 January 2021
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inferred from DOI database lookup
Human TH1 and TH2 subsets: doubt no more
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
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7 January 2021
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Interferon-gamma and B cell stimulatory factor-1 reciprocally regulate Ig isotype production
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
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7 January 2021
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Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
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7 January 2021
based on heuristic
inferred from DOI database lookup
Human toll-like receptor 2 confers responsiveness to bacterial lipopolysaccharide
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
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7 January 2021
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inferred from DOI database lookup
Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
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7 January 2021
based on heuristic
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Bacterial cell wall products as adjuvants: early interferon gamma as a marker for adjuvants that enhance protective immunity
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Safety and immunogenicity of a hepatitis B vaccine formulated with a novel adjuvant system
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure/function studies of QS-21 adjuvant: assessment of triterpene aldehyde and glucuronic acid roles in adjuvant function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Action of Saponin on Biological Cell Membranes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
QS-21: a water-soluble triterpene glycoside adjuvant
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phase 1 trial of immunological adjuvant QS-21 with a GM2 ganglioside-keyhole limpet haemocyanin conjugate vaccine in patients with malignant melanoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of systemic and mucosal immune responses to human immunodeficiency virus type 1 by a DNA vaccine formulated with QS-21 saponin adjuvant via intramuscular and intranasal routes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CpG motifs in bacterial DNA trigger direct B-cell activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA as an adjuvant: capacity of insect DNA and synthetic oligodeoxynucleotides to augment T cell responses to specific antigen
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CpG DNA, a novel immune enhancer for systemic and mucosal immunization with influenza virus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CpG motifs as immune adjuvants
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Use of cellular and cytokine adjuvants in the immunotherapy of cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
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7 January 2021
based on heuristic
inferred from DOI database lookup
An adjuvant formulation that selectively elicits the formation of antibodies of protective isotypes and of cell-mediated immunity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Enhancement of humoral response against human influenza vaccine with the simple submicron oil/water emulsion adjuvant MF59.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Recent advances in vaccine adjuvants: the development of MF59 emulsion and polymeric microparticles
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
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7 January 2021
based on heuristic
inferred from DOI database lookup
MF59 adjuvant enhances the immunogenicity of influenza vaccine in both young and old mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The adjuvant MF59 increases the immunogenicity and protective efficacy of subunit influenza vaccine in mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MF59 adjuvant enhances the antibody response to recombinant hepatitis B surface antigen vaccine in primates
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MF59 adjuvant enhances antibody responses of infant baboons immunized with Haemophilus influenzae type b and Neisseria meningitidis group C oligosaccharide-CRM197 conjugate vaccine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
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7 January 2021
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Dendritic cells internalize vaccine adjuvant after intramuscular injection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
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7 January 2021
based on heuristic
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Clinical and immunologic responses to human immunodeficiency virus (HIV) type 1SF2 gp120 subunit vaccine combined with MF59 adjuvant with or without muramyl tripeptide dipalmitoyl phosphatidylethanolamine in non-HIV-infected human volunteers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
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7 January 2021
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A recombinant glycoprotein vaccine for herpes simplex virus type 2: safety and immunogenicity [corrected]
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
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7 January 2021
based on heuristic
inferred from DOI database lookup
Immunization against the murine malaria parasite Plasmodium yoelii using a recombinant protein with adjuvants developed for clinical use.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A preliminary evaluation of a recombinant circumsporozoite protein vaccine against Plasmodium falciparum malaria. RTS,S Malaria Vaccine Evaluation Group
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
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7 January 2021
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Immunological adjuvants: a role for liposomes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
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7 January 2021
based on heuristic
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Immunogenicity and protectivity of a new liposomal hepatitis A vaccine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
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7 January 2021
based on heuristic
inferred from DOI database lookup
Targeting immune response induction with cochleate and liposome-based vaccines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
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7 January 2021
based on heuristic
inferred from DOI database lookup
ISCOMs and other saponin based adjuvants
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
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7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of protective immunity against influenza virus in a macaque model: comparison of conventional and iscom vaccines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
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7 January 2021
based on heuristic
inferred from DOI database lookup
Biodegradable microspheres in drug delivery
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Improving protein therapeutics with sustained-release formulations
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Controlled release microparticles for vaccine development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Biodegradable and biocompatible poly(DL-lactide-co-glycolide) microspheres as an adjuvant for staphylococcal enterotoxin B toxoid which enhances the level of toxin-neutralizing antibodies.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Long-term antibody responses in mice following subcutaneous immunization with ovalbumin entrapped in biodegradable microparticles
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immunization with a soluble recombinant HIV protein entrapped in biodegradable microparticles induces HIV-specific CD8+ cytotoxic T lymphocytes and CD4+ Th1 cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
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7 January 2021
based on heuristic
inferred from DOI database lookup
Synthetic peptides entrapped in microparticles can elicit cytotoxic T cell activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Microspheres containing plasmid-encoded antigens elicit cytotoxic T-cell responses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Development of adjuvant-active nonionic block copolymers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Poly[di(carboxylatophenoxy)phosphazene] (PCPP) is a potent immunoadjuvant for an influenza vaccine.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synthesis and assembly of hepatitis B virus surface antigen particles in yeast
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Priming of class I-restricted cytotoxic T lymphocytes by vaccination with recombinant protein antigens
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A protein particle vaccine containing multiple malaria epitopes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Optimism over vaccines administered via mucosal surfaces.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Salivary, gut, vaginal and nasal antibody responses after oral immunization with biodegradable microparticles.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Orally administered microencapsulated Bordetella pertussis fimbriae protect mice from B. pertussis respiratory infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immune responses and protection against Bordetella pertussis infection after intranasal immunization of mice with filamentous haemagglutinin in solution or incorporated in biodegradable microparticles
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oral immunization with an anti-idiotypic antibody to the exoglycolipid antigen protects against experimental Chlamydia trachomatis infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protective immunity against Salmonella typhimurium elicited in mice by oral vaccination with phosphorylcholine encapsulated in poly(DL-lactide-co-glycolide) microspheres
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protection against vaginal SIV transmission with microencapsulated vaccine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intranasal immunization of mice with herpes simplex virus type 2 recombinant gD2: the effect of adjuvants on mucosal and serum antibody responses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Biologically erodable microspheres as potential oral drug delivery systems
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Poly(DL-lactide-co-glycolide)-encapsulated plasmid DNA elicits systemic and mucosal antibody responses to encoded protein after oral administration.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PLGA microspheres containing plasmid DNA: preservation of supercoiled DNA via cryopreparation and carbohydrate stabilization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutants of Escherichia coli heat-labile toxin lacking ADP-ribosyltransferase activity act as nontoxic, mucosal adjuvants
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dissociation of Escherichia coli heat-labile enterotoxin adjuvanticity from ADP-ribosyltransferase activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of antigen-specific antibodies in vaginal secretions by using a nontoxic mutant of heat-labile enterotoxin as a mucosal adjuvant
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mucosal adjuvanticity and immunogenicity of LTR72, a novel mutant of Escherichia coli heat-labile enterotoxin with partial knockout of ADP-ribosyltransferase activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protection against Helicobacter pylori infection in mice by intragastric vaccination with H. pylori antigens is achieved using a non-toxic mutant of E. coli heat-labile enterotoxin (LT) as adjuvant.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure and mucosal adjuvanticity of cholera and Escherichia coli heat-labile enterotoxins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Skin immunization made possible by cholera toxin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Placebo-controlled trial of vaccination with recombinant glycoprotein D of herpes simplex virus type 2 for immunotherapy of genital herpes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immune responses of mice and human breast cancer patients following immunization with synthetic sialyl-Tn conjugated to KLH plus detox adjuvant
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cancer-associated MUC1 mucin inhibits human T-cell proliferation, which is reversible by IL-2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Therapeutic intragastric vaccination against Helicobacter pylori in mice eradicates an otherwise chronic infection and confers protection against reinfection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oral tolerance: immune mechanisms and treatment of autoimmune diseases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Microparticles and polymers for the mucosal delivery of vaccines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted delivery of antigen to hamster nasal lymphoid tissue with M-cell-directed lectins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lectin-bearing polymerized liposomes as potential oral vaccine carriers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ulex europaeus 1 lectin targets microspheres to mouse Peyer's patch M-cells in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Enhanced oral uptake of tomato lectin-conjugated nanoparticles in the rat
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HIV-1-specific cell-mediated immune responses induced by DNA vaccination were enhanced by mannan-coated liposomes and inhibited by anti-interferon-gamma antibody
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeting HIV proteins to the major histocompatibility complex class I processing pathway with a novel gp120-anthrax toxin fusion protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F15058
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/15058
1 reference
stated in
Europe PubMed Central
PubMed ID
10545912
retrieved
29 July 2017
PubMed ID
10545912
1 reference
stated in
Europe PubMed Central
PubMed ID
10545912
retrieved
29 July 2017
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