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Mutation of Glu-166 blocks the substrate-induced dimerization of SARS coronavirus main protease.
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scholarly article
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stated in
Europe PubMed Central
PMC publication ID
2849084
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20371333%20AND%20SRC:MED&resulttype=core&format=json
retrieved
30 January 2020
title
Mutation of Glu-166 blocks the substrate-induced dimerization of SARS coronavirus main protease
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
2849084
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20371333%20AND%20SRC:MED&resulttype=core&format=json
retrieved
30 January 2020
main subject
SARS-CoV-1
1 reference
based on heuristic
inferred from title
3C-like proteinase [SARS-Cov]
0 references
Coronaviridae
1 reference
based on heuristic
inferred from title
author
Chi-Yuan Chou
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
2849084
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20371333%20AND%20SRC:MED&resulttype=core&format=json
retrieved
30 January 2020
author name string
Shu-Chun Cheng
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
2849084
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20371333%20AND%20SRC:MED&resulttype=core&format=json
retrieved
30 January 2020
Gu-Gang Chang
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
2849084
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20371333%20AND%20SRC:MED&resulttype=core&format=json
retrieved
30 January 2020
language of work or name
English
0 references
publication date
1 April 2010
1 reference
stated in
Europe PubMed Central
PMC publication ID
2849084
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20371333%20AND%20SRC:MED&resulttype=core&format=json
retrieved
30 January 2020
number of pages
10
1 reference
based on heuristic
inferred from page(s)
published in
Biophysical Journal
1 reference
stated in
Europe PubMed Central
PMC publication ID
2849084
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20371333%20AND%20SRC:MED&resulttype=core&format=json
retrieved
30 January 2020
volume
98
1 reference
stated in
Europe PubMed Central
PMC publication ID
2849084
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20371333%20AND%20SRC:MED&resulttype=core&format=json
retrieved
30 January 2020
issue
7
1 reference
stated in
Europe PubMed Central
PMC publication ID
2849084
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20371333%20AND%20SRC:MED&resulttype=core&format=json
retrieved
30 January 2020
page(s)
1327-1336
1 reference
stated in
Europe PubMed Central
PMC publication ID
2849084
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20371333%20AND%20SRC:MED&resulttype=core&format=json
retrieved
30 January 2020
describes a project that uses
plasmid design
1 reference
based on heuristic
inferred from Methods description
Escherichia coli
1 reference
based on heuristic
inferred from Methods description
protein purification
1 reference
based on heuristic
inferred from Methods description
SDS-PAGE
1 reference
based on heuristic
inferred from Methods description
enzyme assay
1 reference
based on heuristic
inferred from Methods description
analytical ultracentrifugation
1 reference
based on heuristic
inferred from Methods description
size-exclusion chromatography
1 reference
based on heuristic
inferred from Methods description
isothermal titration calorimetry
1 reference
based on heuristic
inferred from Methods description
cites work
Two adjacent mutations on the dimer interface of SARS coronavirus 3C-like protease cause different conformational changes in crystal structure
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849084
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22 June 2018
C-terminal domain of sars-CoV main protease can form a 3d domain-swapped dimer
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849084
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22 June 2018
Development of Broad-Spectrum Halomethyl Ketone Inhibitors Against Coronavirus Main Protease 3CLpro
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PubMed Central
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22 June 2018
Structure of the Main Protease from a Global Infectious Human Coronavirus, HCoV-HKU1
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22 June 2018
Mechanism for Controlling the Dimer-Monomer Switch and Coupling Dimerization to Catalysis of the Severe Acute Respiratory Syndrome Coronavirus 3C-Like Protease
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849084
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22 June 2018
Structures of Two Coronavirus Main Proteases: Implications for Substrate Binding and Antiviral Drug Design
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22 June 2018
Mutation of Gly-11 on the dimer interface results in the complete crystallographic dimer dissociation of severe acute respiratory syndrome coronavirus 3C-like protease: crystal structure with molecular dynamics simulations
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PubMed Central
reference URL
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22 June 2018
Crystal structure of murine CstF-77: dimeric association and implications for polyadenylation of mRNA precursors
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reference URL
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22 June 2018
Long-range cooperative interactions modulate dimerization in SARS 3CLpro.
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reference URL
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22 June 2018
Reversible unfolding of the severe acute respiratory syndrome coronavirus main protease in guanidinium chloride
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849084
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22 June 2018
Macromolecular size-and-shape distributions by sedimentation velocity analytical ultracentrifugation.
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PubMed Central
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22 June 2018
Computational docking and solution x-ray scattering predict a membrane-interacting role for the histone domain of the Ras activator son of sevenless
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22 June 2018
Design of wide-spectrum inhibitors targeting coronavirus main proteases
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22 June 2018
Characterization and complete genome sequence of a novel coronavirus, coronavirus HKU1, from patients with pneumonia
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22 June 2018
Structural variation in human apolipoprotein E3 and E4: secondary structure, tertiary structure, and size distribution
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849084
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22 June 2018
Identification of a new human coronavirus
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PubMed Central
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22 June 2018
The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor
1 reference
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PubMed Central
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22 June 2018
Biosynthesis, Purification, and Substrate Specificity of Severe Acute Respiratory Syndrome Coronavirus 3C-like Proteinase
1 reference
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PubMed Central
reference URL
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22 June 2018
On the analysis of protein self-association by sedimentation velocity analytical ultracentrifugation
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849084
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22 June 2018
The 3C-like proteinase of an invertebrate nidovirus links coronavirus and potyvirus homologs
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849084
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22 June 2018
Structure of coronavirus main proteinase reveals combination of a chymotrypsin fold with an extra alpha-helical domain
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849084
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22 June 2018
Mutational analysis of the active centre of coronavirus 3C-like proteases
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849084
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22 June 2018
Size-Distribution Analysis of Macromolecules by Sedimentation Velocity Ultracentrifugation and Lamm Equation Modeling
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849084
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22 June 2018
A bicarbonate ion as a general base in the mechanism of peptide hydrolysis by dizinc leucine aminopeptidase
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PubMed Central
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22 June 2018
Correlation between dissociation and catalysis of SARS-CoV main protease.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849084
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30 October 2018
Steady-state and pre-steady-state kinetic evaluation of severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro cysteine protease: development of an ion-pair model for catalysis.
1 reference
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PubMed Central
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Is dimerization required for the catalytic activity of bacterial biotin carboxylase?
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30 October 2018
Critical assessment of important regions in the subunit association and catalytic action of the severe acute respiratory syndrome coronavirus main protease.
1 reference
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PubMed Central
reference URL
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30 October 2018
Mechanism of the maturation process of SARS-CoV 3CL protease
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849084
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30 October 2018
Severe acute respiratory syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849084
retrieved
30 October 2018
Quaternary structure of the severe acute respiratory syndrome (SARS) coronavirus main protease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849084
retrieved
30 October 2018
3C-like proteinase from SARS coronavirus catalyzes substrate hydrolysis by a general base mechanism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849084
retrieved
30 October 2018
Conservation of substrate specificities among coronavirus main proteases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849084
retrieved
30 October 2018
Only one protomer is active in the dimer of SARS 3C-like proteinase
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20371333
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.BPJ.2009.12.4272
1 reference
stated in
Europe PubMed Central
PMC publication ID
2849084
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20371333%20AND%20SRC:MED&resulttype=core&format=json
retrieved
30 January 2020
PMC publication ID
2849084
1 reference
stated in
Europe PubMed Central
PMC publication ID
2849084
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20371333%20AND%20SRC:MED&resulttype=core&format=json
retrieved
30 January 2020
PubMed publication ID
20371333
1 reference
stated in
Europe PubMed Central
PMC publication ID
2849084
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20371333%20AND%20SRC:MED&resulttype=core&format=json
retrieved
30 January 2020
ResearchGate publication ID
43049629
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