(Q33772643)

29 July 2017

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title

Tools of the trade: use of dominant-inhibitory mutants of Ras-family GTPases (English)

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29 July 2017

Feig LA

1

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29 July 2017

1 June 1999

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29 July 2017

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29 July 2017

1

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29 July 2017

E25-7

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29 July 2017

2

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https://scigraph.springernature.com/pub.10.1038/10018

29 July 2017

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cites work

Function and regulation of ras.

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7 January 2021

Signal transduction from multiple Ras effectors

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7 January 2021

Mutant ras-encoded proteins with altered nucleotide binding exert dominant biological effects

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7 January 2021

Inhibition of NIH 3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP.

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7 January 2021

Dominant yeast and mammalian RAS mutants that interfere with the CDC25-dependent activation of wild-type RAS in Saccharomyces cerevisiae

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7 January 2021

Identification of residues critical for Ras(17N) growth-inhibitory phenotype and for Ras interaction with guanine nucleotide exchange factors

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7 January 2021

Distal switch II region of Ras2p is required for interaction with guanine nucleotide exchange factor.

1 reference

7 January 2021

Dominant inhibitory mutations in the Mg(2+)-binding site of RasH prevent its activation by GTP

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7 January 2021

Studies on the structure and mechanism of H-ras p21

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7 January 2021

Dominant inhibitory Ras mutants selectively inhibit the activity of either cellular or oncogenic Ras.

1 reference

7 January 2021

Identification of a novel RalGDS-related protein as a candidate effector for Ras and Rap1

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7 January 2021

Kinetic analysis by fluorescence of the interaction between Ras and the catalytic domain of the guanine nucleotide exchange factor Cdc25Mm

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7 January 2021

Influence of guanine nucleotides on complex formation between Ras and CDC25 proteins

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7 January 2021

Preferential inhibition of the oncogenic form of RasH by mutations in the GAP binding/"effector" domain

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7 January 2021

TC21 causes transformation by Raf-independent signaling pathways

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7 January 2021

Activation of the Raf/MAP kinase cascade by the Ras-related protein TC21 is required for the TC21-mediated transformation of NIH 3T3 cells

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7 January 2021

Activation of R-Ras by Ras-guanine nucleotide-releasing factor

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7 January 2021

Guanine nucleotide exchange catalyzed by dbl oncogene product

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7 January 2021

Structural and Functional Analysis of a Mutant Ras Protein That Is Insensitive to Nitric Oxide Activation†

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7 January 2021

Stimulation of p21 ras upon T-cell activation

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7 January 2021

Requirement of Ras-GTP-Raf Complexes for Activation of Raf-1 by Protein Kinase C

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7 January 2021

Effect of a dominant inhibitory Ha-ras mutation on neuronal differentiation of PC12 cells

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7 January 2021

Biochemical characterization of C3G: an exchange factor that discriminates between Rap1 and Rap2 and is not inhibited by Rap1A(S17N).

1 reference

7 January 2021

The 2.2 A crystal structure of transducin-alpha complexed with GTP gamma S

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7 January 2021

A mutation in the putative Mg(2+)-binding site of Gs alpha prevents its activation by receptors

1 reference

7 January 2021

Identifiers

DOI

10.1038/10018

1 reference

PubMed ID

10559887

Dimensions Publication ID

29 July 2017

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1 reference

PubMed ID

10559887