(Q33776166)

29 July 2017

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title

Hemodynamic shear stress and the endothelium in cardiovascular pathophysiology (English)

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29 July 2017

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Peter F Davies

1

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PubMed ID

19029993

29 July 2017

language of work or name

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25 November 2008

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Nature Clinical Practice Cardiovascular Medicine

29 July 2017

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29 July 2017

6

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29 July 2017

16-26

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29 July 2017

1

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https://scigraph.springernature.com/pub.10.1038/ncpcardio1397

29 July 2017

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cites work

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4 July 2018

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Mapping the dynamics of shear stress-induced structural changes in endothelial cells

4 July 2018

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Vascular remodeling of the mouse yolk sac requires hemodynamic force

4 July 2018

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Distinctive expression of chemokines and transforming growth factor-beta signaling in human arterial endothelium during atherosclerosis

4 July 2018

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Nanomechanotransduction and interphase nuclear organization influence on genomic control

4 July 2018

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4 July 2018

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Biomechanical modulation of endothelial phenotype: implications for health and disease

4 July 2018

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Adventures in vascular biology: a tale of two mediators

4 July 2018

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Role of small GTPases in endothelial cytoskeletal dynamics and the shear stress response

4 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851404

Flow imaging and computing: large artery hemodynamics

4 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851404

Integration of flow-dependent endothelial phenotypes by Kruppel-like factor 2

4 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851404

Endothelial protein kinase C isoform identity and differential activity of PKCzeta in an athero-susceptible region of porcine aorta

4 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851404

Effect of exercise training on endothelium-derived nitric oxide function in humans.

4 July 2018

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Primary cilia of human endothelial cells disassemble under laminar shear stress

4 July 2018

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Coexisting proinflammatory and antioxidative endothelial transcription profiles in a disturbed flow region of the adult porcine aorta.

4 July 2018

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Mapping mechanical strain of an endogenous cytoskeletal network in living endothelial cells

4 July 2018

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Transitional flow at the venous anastomosis of an arteriovenous graft: potential activation of the ERK1/2 mechanotransduction pathway

4 July 2018

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Beneficial effects of antioxidants and L-arginine on oxidation-sensitive gene expression and endothelial NO synthase activity at sites of disturbed shear stress

4 July 2018

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Role of integrins in endothelial mechanosensing of shear stress

4 July 2018

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Prolonged fluid shear stress induces a distinct set of endothelial cell genes, most specifically lung Krüppel-like factor (KLF2)

4 July 2018

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4 July 2018

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4 July 2018

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The cytoskeleton under external fluid mechanical forces: hemodynamic forces acting on the endothelium

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851404

Rapid flow-induced responses in endothelial cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851404

Is PECAM-1 a mechanoresponsive molecule?

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851404

Coronary artery injury and the biology of atherosclerosis: inflammation, thrombosis, and stabilization

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851404

The NF-kappa B signal transduction pathway in aortic endothelial cells is primed for activation in regions predisposed to atherosclerotic lesion formation.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851404

A spatial approach to transcriptional profiling: mechanotransduction and the focal origin of atherosclerosis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851404

Pressure-jump studies of the folding/unfolding of trp repressor.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851404

Demonstration of mechanical connections between integrins, cytoskeletal filaments, and nucleoplasm that stabilize nuclear structure

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851404

Identification of distinct luminal domains for macromolecules, erythrocytes, and leukocytes within mammalian capillaries

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851404

Mechanism of endothelial cell shape change and cytoskeletal remodeling in response to fluid shear stress.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851404

Fluid shear stress induces a biphasic response of human monocyte chemotactic protein 1 gene expression in vascular endothelium

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851404

Quantitative studies of endothelial cell adhesion. Directional remodeling of focal adhesion sites in response to flow forces

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851404

Flow-mediated endothelial mechanotransduction

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851404

Influence of hemodynamic forces on vascular endothelial function. In vitro studies of shear stress and pinocytosis in bovine aortic cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851404

The elongation and orientation of cultured endothelial cells in response to shear stress.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851404

Turbulent fluid shear stress induces vascular endothelial cell turnover in vitro

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851404

Endothelial cilia in human aortic atherosclerotic lesions

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851404

Hemodynamics and atherosclerosis. Insights and perspectives gained from studies of human arteries.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851404

Mathematical analysis of mural thrombogenesis. Concentration profiles of platelet-activating agents and effects of viscous shear flow

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851404

Haemodynamic shear stress activates a K+ current in vascular endothelial cells.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851404

A quantitative study of the localization of atherosclerotic lesions in the rabbit aorta

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851404

Endothelial nitric oxide synthase gene expression during murine embryogenesis: commencement of expression in the embryo occurs with the establishment of a unidirectional circulatory system.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851404

Blood flow patterns in the proximal human coronary arteries: relationship to atherosclerotic plaque occurrence.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851404

Flow patterns in three-dimensional porcine epicardial coronary arterial tree.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851404

Glycocalyx modulates the motility and proliferative response of vascular endothelium to fluid shear stress.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851404

Hemodynamic shear stresses in mouse aortas: implications for atherogenesis.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851404

Flow-activated chloride channels in vascular endothelium. Shear stress sensitivity, desensitization dynamics, and physiological implications.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851404

Atherosclerotic lesion size and vulnerability are determined by patterns of fluid shear stress.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851404

Spatial distribution of platelet deposition in stented arterial models under physiologic flow.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851404

A mechanosensory complex that mediates the endothelial cell response to fluid shear stress

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851404

Shear stress affects the intracellular distribution of eNOS: direct demonstration by a novel in vivo technique.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851404

Strut position, blood flow, and drug deposition: implications for single and overlapping drug-eluting stents.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851404

Heparan Sulfate Proteoglycan Is a Mechanosensor on Endothelial Cells

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851404

Subcellular distribution of shear stress at the surface of flow-aligned and nonaligned endothelial monolayers.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851404

Endothelial primary cilia in areas of disturbed flow are at the base of atherosclerosis

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851404

Patterns of vascular cell adhesion molecule-1 and intercellular adhesion molecule-1 expression in rabbit and mouse atherosclerotic lesions and at sites predisposed to lesion formation

30 October 2018

1 reference

12 December 2020

Control of stress propagation in the cytoplasm by prestress and loading frequency

1 reference

12 December 2020

Effect of the endothelial surface layer on transmission of fluid shear stress to endothelial cells

1 reference

12 December 2020

Intracoronary stenting and angiographic results: strut thickness effect on restenosis outcome (ISAR-STEREO) trial

1 reference

12 December 2020

Mechanosensitive endothelial gene expression profiles: scripts for the role of hemodynamics in atherogenesis?

1 reference

12 December 2020

Arterial Wall Shear and Distribution of Early Atheroma in Man

1 reference

12 December 2020

Dynamics of arterial flow

1 reference

12 December 2020

The Dynamic Response of Vascular Endothelial Cells to Fluid Shear Stress

1 reference

12 December 2020

Reductions in arterial diameter produced by chronic decreases in blood flow are endothelium-dependent

1 reference

12 December 2020

Crucial role of endothelium in the vasodilator response to increased flow in vivo

1 reference

12 December 2020

Flow patterns and spatial distribution of atherosclerotic lesions in human coronary arteries

1 reference

12 December 2020

Vascular endothelium responds to fluid shear stress gradients

1 reference

12 December 2020

Phosphorylation of endothelial nitric oxide synthase in response to fluid shear stress

1 reference

12 December 2020

Increased blood flow induces regression of intimal hyperplasia

1 reference

12 December 2020

Influence of oscillatory and unidirectional flow environments on the expression of endothelin and nitric oxide synthase in cultured endothelial cells

1 reference

12 December 2020

Biomechanical forces in atherosclerosis-resistant vascular regions regulate endothelial redox balance via phosphoinositol 3-kinase/Akt-dependent activation of Nrf2

1 reference

12 December 2020

Increased endothelial mitogen-activated protein kinase phosphatase-1 expression suppresses proinflammatory activation at sites that are resistant to atherosclerosis

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCPCARDIO1397

1 reference

PubMed ID

19029993

Dimensions Publication ID

29 July 2017

0 references

1 reference

29 July 2017

1 reference

PubMed ID

19029993