(Q33777110)

English

Accelerated accumulation of lipofuscin pigments in the RPE of a mouse model for ABCA4-mediated retinal dystrophies following Vitamin A supplementation

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Accelerated accumulation of lipofuscin pigments in the RPE of a mouse model for ABCA4-mediated retinal dystrophies following Vitamin A supplementation (English)

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

0 references

1 reference

based on heuristic

inferred from title

author name string

Roxana A Radu

1

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Quan Yuan

2

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Jane Hu

3

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Jennifer H Peng

4

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Marcia Lloyd

5

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Steven Nusinowitz

6

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Dean Bok

7

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Gabriel H Travis

8

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

language of work or name

0 references

publication date

30 May 2008

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Investigative Ophthalmology Visual Science

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

49

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

9

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

3821-3829

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

The all-trans-retinal dimer series of lipofuscin pigments in retinal pigment epithelial cells in a recessive Stargardt disease model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851626

28 July 2018

Characterization of dihydro-A2PE: an intermediate in the A2E biosynthetic pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851626

28 July 2018

Retinitis pigmentosa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851626

28 July 2018

Reductions in Serum Vitamin A Arrest Accumulation of Toxic Retinal Fluorophores: A Potential Therapy for Treatment of Lipofuscin-Based Retinal Diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851626

28 July 2018

Isolation and characterization of a retinal pigment epithelial cell fluorophore: an all-trans-retinal dimer conjugate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851626

28 July 2018

Changes in fundus autofluorescence in patients with age-related maculopathy. Correlation to visual function: a prospective study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851626

28 July 2018

Microarray-based mutation analysis of the ABCA4 (ABCR) gene in autosomal recessive cone-rod dystrophy and retinitis pigmentosa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851626

28 July 2018

Light exposure stimulates formation of A2E oxiranes in a mouse model of Stargardt's macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851626

28 July 2018

Treatment with isotretinoin inhibits lipofuscin accumulation in a mouse model of recessive Stargardt's macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851626

28 July 2018

A2E-epoxides damage DNA in retinal pigment epithelial cells. Vitamin E and other antioxidants inhibit A2E-epoxide formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851626

28 July 2018

Retinol-binding protein-deficient mice: biochemical basis for impaired vision

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851626

28 July 2018

The lipofuscin component A2E selectively inhibits phagolysosomal degradation of photoreceptor phospholipid by the retinal pigment epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851626

28 July 2018

Fundus autofluorescence in patients with age-related macular degeneration and high risk of visual loss

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851626

28 July 2018

Delayed dark-adaptation and lipofuscin accumulation in abcr+/- mice: implications for involvement of ABCR in age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851626

28 July 2018

Inhibition of the visual cycle in vivo by 13-cis retinoic acid protects from light damage and provides a mechanism for night blindness in isotretinoin therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851626

28 July 2018

Biosynthesis of a major lipofuscin fluorophore in mice and humans with ABCR-mediated retinal and macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851626

28 July 2018

A2E, a lipofuscin fluorophore, in human retinal pigmented epithelial cells in culture.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851626

28 July 2018

Insights into the function of Rim protein in photoreceptors and etiology of Stargardt's disease from the phenotype in abcr knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851626

28 July 2018

Retinal stimulates ATP hydrolysis by purified and reconstituted ABCR, the photoreceptor-specific ATP-binding cassette transporter responsible for Stargardt disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851626

28 July 2018

Stargardt's ABCR is localized to the disc membrane of retinal rod outer segments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851626

28 July 2018

The photoreceptor rim protein is an ABC transporter encoded by the gene for recessive Stargardt's disease (ABCR)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851626

28 July 2018

The 220-kDa rim protein of retinal rod outer segments is a member of the ABC transporter superfamily

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851626

28 July 2018

A photoreceptor cell-specific ATP-binding transporter gene (ABCR) is mutated in recessive Stargardt macular dystrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851626

28 July 2018

A randomized trial of vitamin A and vitamin E supplementation for retinitis pigmentosa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851626

28 July 2018

Light adaptation of human rod receptors: the leading edge of the human a-wave and models of rod receptor activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851626

28 July 2018

Histopathology and immunocytochemistry of the neurosensory retina in fundus flavimaculatus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851626

28 July 2018

The molecular basis of retinoic acid induced night blindness

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851626

28 July 2018

Classification of fundus autofluorescence patterns in early age-related macular disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851626

30 October 2018

Rpe65 is the retinoid isomerase in bovine retinal pigment epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851626

30 October 2018

Fundus autofluorescence in children and teenagers with hereditary retinal diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851626

30 October 2018

Partial agonism in a G Protein-coupled receptor: role of the retinal ring structure in rhodopsin activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851626

30 October 2018

The spectrum of retinal phenotypes caused by mutations in the ABCA4 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851626

30 October 2018

N-retinylidene-phosphatidylethanolamine is the preferred retinoid substrate for the photoreceptor-specific ABC transporter ABCA4 (ABCR).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851626

30 October 2018

Electroretinographic evidence for altered phototransduction gain and slowed recovery from photobleaches in albino mice with a MET450 variant in RPE65

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851626

30 October 2018

Formation of a nonaoxirane from A2E, a lipofuscin fluorophore related to macular degeneration, and evidence of singlet oxygen involvement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851626

30 October 2018

Interaction of A2E with model membranes. Implications to the pathogenesis of age-related macular degeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851626

30 October 2018

Blue light-induced apoptosis of A2E-containing RPE: involvement of caspase-3 and protection by Bcl-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851626

30 October 2018

The lipofuscin fluorophore A2E mediates blue light-induced damage to retinal pigmented epithelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851626

30 October 2018

Isolation and one-step preparation of A2E and iso-A2E, fluorophores from human retinal pigment epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851626

30 October 2018

Rod phototransduction in retinitis pigmentosa: estimation and interpretation of parameters derived from the rod a-wave.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851626

30 October 2018

Allelic variation in ABCR associated with Stargardt disease but not age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851626

30 October 2018

Retinal pigment epithelial abnormalities in fundus flavimaculatus: a light and electron microscopic study

1 reference

https://pubmed.ncbi.nlm.nih.gov/18515570

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevalence of retinitis pigmentosa in Maine

1 reference

https://pubmed.ncbi.nlm.nih.gov/18515570

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Delayed rod dark adaptation in patients with Stargardt's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/18515570

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro interaction of fenretinide with plasma retinol-binding protein and its functional consequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/18515570

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retinal age pigments generated by self-assembling lysosomotropic detergents

1 reference

https://pubmed.ncbi.nlm.nih.gov/18515570

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo fluorescence of the ocular fundus exhibits retinal pigment epithelium lipofuscin characteristics

1 reference

https://pubmed.ncbi.nlm.nih.gov/18515570

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Opsin/all-trans-retinal complex activates transducin by different mechanisms than photolyzed rhodopsin

1 reference

https://pubmed.ncbi.nlm.nih.gov/18515570

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipofuscin in the retina: quantitative assay for an unprecedented autofluorescent compound (pyridinium bis-retinoid, A2-E) of ocular age pigment

1 reference

https://pubmed.ncbi.nlm.nih.gov/18515570

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Photophysical Studies of A2-E, Putative Precursor of Lipofuscin, in Human Retinal Pigment Epithelial Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18515570

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of native retinal fluorophores involved in biosynthesis of A2E and lipofuscin-associated retinopathies

1 reference

https://pubmed.ncbi.nlm.nih.gov/18515570

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Substrate specificities and 13-cis-retinoic acid inhibition of human, mouse and bovine cis-retinol dehydrogenases

1 reference

https://pubmed.ncbi.nlm.nih.gov/18515570

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Indocyanine green angiography in Fundus flavimaculatus

1 reference

https://pubmed.ncbi.nlm.nih.gov/18515570

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dietary reference intakes for the antioxidant nutrients: vitamin C, vitamin E, selenium, and carotenoids

1 reference

https://pubmed.ncbi.nlm.nih.gov/18515570

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Photodamage to human RPE cells by A2-E, a retinoid component of lipofuscin

1 reference

https://pubmed.ncbi.nlm.nih.gov/18515570

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-related Macular Degeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/18515570

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-related accumulation and spatial distribution of lipofuscin in RPE of normal subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/18515570

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1167/IOVS.07-1470

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q33777110&oldid=1965071170"