(Q33781957)

29 July 2017

1 reference

title

Development of eptifibatide (English)

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29 July 2017

R M Scarborough

1

1 reference

PubMed ID

10577440

29 July 2017

language of work or name

English

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publication date

1 December 1999

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29 July 2017

American Heart Journal

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29 July 2017

138

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29 July 2017

1093-1104

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29 July 2017

6 Pt 1

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Novel antithrombotic therapeutics targeted against platelet glycoprotein IIb/IIIa

29 July 2017

1 reference

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The role of intracoronary thrombus in unstable angina: angiographic assessment and thrombolytic therapy during ongoing anginal attacks

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Prevalence of total coronary occlusion during the early hours of transmural myocardial infarction

7 January 2021

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Percutaneous transluminal coronary angioplasty

7 January 2021

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Safety and antiplatelet effect of murine monoclonal antibody 7E3 Fab directed against platelet glycoprotein IIb/IIIa in patients undergoing elective coronary angioplasty

7 January 2021

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Profound inhibition of platelet aggregation with monoclonal antibody 7E3 Fab after thrombolytic therapy. Results of the Thrombolysis and Angioplasty in Myocardial Infarction (TAMI) 8 Pilot Study

7 January 2021

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The immunogenicity of the 7E3 murine monoclonal Fab antibody fragment variable region is dramatically reduced in humans by substitution of human for murine constant regions

7 January 2021

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Blockade of platelet GPIIb/IIIa receptors as an antithrombotic strategy

7 January 2021

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Use of a monoclonal antibody directed against the platelet glycoprotein IIb/IIIa receptor in high-risk coronary angioplasty

7 January 2021

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Pharmacodynamics of chimeric glycoprotein IIb/IIIa integrin antiplatelet antibody Fab 7E3 in high-risk coronary angioplasty.

7 January 2021

1 reference

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Shear-induced platelet aggregation is inhibited by in vivo infusion of an anti-glycoprotein IIb/IIIa antibody fragment, c7E3 Fab, in patients undergoing coronary angioplasty

7 January 2021

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Abciximab (c7E3 Fab). A review of its pharmacology and therapeutic potential in ischaemic heart disease

7 January 2021

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Role of platelets in restenosis after percutaneous coronary revascularization

7 January 2021

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7E3 monoclonal antibody directed against the platelet glycoprotein IIb/IIIa cross-reacts with the leukocyte integrin Mac-1 and blocks adhesion to fibrinogen and ICAM-1.

7 January 2021

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Disintegrins: a family of integrin inhibitory proteins from viper venoms

7 January 2021

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Clinical pharmacology of eptifibatide

7 January 2021

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Effect of Ca2+ on GP IIb-IIIa interactions with integrilin: enhanced GP IIb-IIIa binding and inhibition of platelet aggregation by reductions in the concentration of ionized calcium in plasma anticoagulated with citrate

7 January 2021

1 reference

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Immediate and reversible platelet inhibition after intravenous administration of a peptide glycoprotein IIb/IIIa inhibitor during percutaneous coronary intervention

7 January 2021

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Early clinical experience with integrelin, an inhibitor of the platelet glycoprotein IIb/IIIa integrin receptor

7 January 2021

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Effects of integrelin, a platelet glycoprotein IIb/IIIa receptor antagonist, in unstable angina. A randomized multicenter trial.

7 January 2021

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Combined accelerated tissue-plasminogen activator and platelet glycoprotein IIb/IIIa integrin receptor blockade with Integrilin in acute myocardial infarction. Results of a randomized, placebo-controlled, dose-ranging trial. IMPACT-AMI Investigators

7 January 2021

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Multicenter, randomized, double-blind, placebo-controlled trial of the platelet integrin glycoprotein IIb/IIIa blocker Integrelin in elective coronary intervention. IMPACT Investigators

7 January 2021

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Impact of eptifibatide on early ischemic events in acute ischemic coronary syndromes: a review of the IMPACT II trial. Integrilin to Minimize Platelet Aggregation and Coronary Thrombosis

7 January 2021

1 reference

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Design and methodology of the PURSUIT trial: evaluating eptifibatide for acute ischemic coronary syndromes. Platelet Glycoprotein IIb-IIIa in Unstable Angina: Receptor Suppression Using Integrilin Therapy

7 January 2021

1 reference

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Inhibition of platelet glycoprotein IIb/IIIa with eptifibatide in patients with acute coronary syndromes

7 January 2021

1 reference

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10.1016/S0002-8703(99)70075-X

7 January 2021

Identifiers

DOI

1 reference

29 July 2017

1 reference

PubMed ID

10577440