(Q33784288)

29 July 2017

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title

Clinical applications of angiogenic growth factors and their inhibitors (English)

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29 July 2017

Ferrara N

1

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29 July 2017

Alitalo K

series ordinal

2

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29 July 2017

language of work or name

English

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publication date

1 December 1999

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29 July 2017

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29 July 2017

5

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29 July 2017

1359-1364

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29 July 2017

12

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https://scigraph.springernature.com/pub.10.1038/70928

29 July 2017

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7 January 2021

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7 January 2021

Signaling angiogenesis and lymphangiogenesis

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Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene

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Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

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Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188

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Fibroblast growth factor-2 (FGF-2) induces vascular endothelial growth factor (VEGF) expression in the endothelial cells of forming capillaries: an autocrine mechanism contributing to angiogenesis

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Angiogenesis and vasculogenesis in treatment of cardiovascular disease.

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Therapeutic angiogenesis. A single intraarterial bolus of vascular endothelial growth factor augments revascularization in a rabbit ischemic hind limb model

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Enhanced revascularization of the ischemic limb by angiogenic therapy

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Synergistic effect of vascular endothelial growth factor and basic fibroblast growth factor on angiogenesis in vivo.

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Potentiated angiogenic effect of scatter factor/hepatocyte growth factor via induction of vascular endothelial growth factor: the case for paracrine amplification of angiogenesis

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Vascular endothelial growth factor-C (VEGF-C/VEGF-2) promotes angiogenesis in the setting of tissue ischemia

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Salvage angiogenesis induced by adenovirus-mediated gene transfer of vascular endothelial growth factor protects against ischemic vascular occlusion

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Magnetic resonance mapping demonstrates benefits of VEGF-induced myocardial angiogenesis

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Basic fibroblast growth factor improves myocardial function in chronically ischemic porcine hearts

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7 January 2021

VEGF administration in chronic myocardial ischemia in pigs

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7 January 2021

Biologic bypass with the use of adenovirus-mediated gene transfer of the complementary deoxyribonucleic acid for vascular endothelial growth factor 121 improves myocardial perfusion and function in the ischemic porcine heart

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Intracoronary gene transfer of fibroblast growth factor-5 increases blood flow and contractile function in an ischemic region of the heart

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Clinical evidence of angiogenesis after arterial gene transfer of phVEGF165 in patient with ischaemic limb

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Constitutive expression of phVEGF165 after intramuscular gene transfer promotes collateral vessel development in patients with critical limb ischemia

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Gene therapy for myocardial angiogenesis: initial clinical results with direct myocardial injection of phVEGF165 as sole therapy for myocardial ischemia

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Treatment of thromboangiitis obliterans (Buerger's disease) by intramuscular gene transfer of vascular endothelial growth factor: preliminary clinical results

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Advances in coronary angioplasty

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7 January 2021

Vascular gene transfer

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7 January 2021

Local delivery of vascular endothelial growth factor accelerates reendothelialization and attenuates intimal hyperplasia in balloon-injured rat carotid artery

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7 January 2021

Vascular endothelial growth factor causes endothelial proliferation after vascular injury

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7 January 2021

VEGF Gene Transfer Reduces Intimal Thickening via Increased Production of Nitric Oxide in Carotid Arteries

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Adenovirus-mediated gene transfer to lower limb artery of patients with chronic critical leg ischemia.

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Intracoronary heparin delivery in humans. Acute feasibility and long-term results

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Stable restoration of the sarcoglycan complex in dystrophic muscle perfused with histamine and a recombinant adeno-associated viral vector

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Transplacental carcinogenesis by stilbestrol

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Block of AIDS-Kaposi's sarcoma (KS) cell growth, angiogenesis, and lesion formation in nude mice by antisense oligonucleotide targeting basic fibroblast growth factor. A novel strategy for the therapy of KS.

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Inhibition of tumor angiogenesis using a soluble receptor establishes a role for Tie2 in pathologic vascular growth

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Antiangiogenic gene therapy targeting the endothelium-specific receptor tyrosine kinase Tie2

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Tumor induction of VEGF promoter activity in stromal cells

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Prognostic significance of vascular endothelial growth factor protein in node-negative breast carcinoma

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High pre-treatment serum level of vascular endothelial growth factor (VEGF) is associated with poor outcome in small-cell lung cancer

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Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

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Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody

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Regional suppression of tumor growth by in vivo transfer of a cDNA encoding a secreted form of the extracellular domain of the flt-1 vascular endothelial growth factor receptor

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Paracrine expression of a native soluble vascular endothelial growth factor receptor inhibits tumor growth, metastasis, and mortality rate

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Preclinical safety evaluation of rhuMAbVEGF, an antiangiogenic humanized monoclonal antibody

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Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders

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Inhibition of vascular endothelial growth factor prevents retinal ischemia-associated iris neovascularization in a nonhuman primate

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Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins

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7 January 2021

2'-Fluoropyrimidine RNA-based aptamers to the 165-amino acid form of vascular endothelial growth factor (VEGF165). Inhibition of receptor binding and VEGF-induced vascular permeability through interactions requiring the exon 7-encoded domain

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7 January 2021

Vascular endothelial growth factor is essential for corpus luteum angiogenesis.

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7 January 2021

Vascular endothelial growth factor as capillary permeability agent in ovarian hyperstimulation syndrome

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7 January 2021

Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor

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7 January 2021

Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis

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7 January 2021

Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4

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7 January 2021

Direct intramuscular injection of plasmid DNA encoding angiopoietin-1 but not angiopoietin-2 augments revascularization in the rabbit ischemic hindlimb

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7 January 2021

Delivery of molecular and cellular medicine to solid tumors

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7 January 2021

Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

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7 January 2021

The angiogenesis induced by HIV-1 tat protein is mediated by the Flk-1/KDR receptor on vascular endothelial cells.

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7 January 2021

G-protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator

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7 January 2021

A novel type of vascular endothelial growth factor, VEGF-E (NZ-7 VEGF), preferentially utilizes KDR/Flk-1 receptor and carries a potent mitotic activity without heparin-binding domain

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7 January 2021

A novel vascular endothelial growth factor encoded by Orf virus, VEGF-E, mediates angiogenesis via signalling through VEGFR-2 (KDR) but not VEGFR-1 (Flt-1) receptor tyrosine kinases

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7 January 2021

Vascular endothelial growth factor (VEGF)-like protein from orf virus NZ2 binds to VEGFR2 and neuropilin-1

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7 January 2021

Increased vascularization in mice overexpressing angiopoietin-1

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7 January 2021

Tie2 receptor ligands, angiopoietin-1 and angiopoietin-2, modulate VEGF-induced postnatal neovascularization

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7 January 2021

VEGF gene delivery to muscle: potential role for vasculogenesis in adults

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7 January 2021

Hyperplasia of lymphatic vessels in VEGF-C transgenic mice

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7 January 2021

VEGF and VEGF-C: specific induction of angiogenesis and lymphangiogenesis in the differentiated avian chorioallantoic membrane

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7 January 2021

Magnetic resonance imaging detects suppression of tumor vascular permeability after administration of antibody to vascular endothelial growth factor

1 reference

7 January 2021

VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation

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7 January 2021

VEGF(165) mediates glomerular endothelial repair

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7 January 2021

Isolation of putative progenitor endothelial cells for angiogenesis

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7 January 2021

KDR receptor: a key marker defining hematopoietic stem cells

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7 January 2021

Ischemia- and cytokine-induced mobilization of bone marrow-derived endothelial progenitor cells for neovascularization

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7 January 2021

Role of alphavbeta3 integrin in the activation of vascular endothelial growth factor receptor-2.

1 reference

7 January 2021

Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis

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7 January 2021

Hereditary lymphedema: evidence for linkage and genetic heterogeneity

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7 January 2021

Identifiers

DOI

10.1038/70928

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Dimensions Publication ID

29 July 2017

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1 reference