(Q33785121)

English

The functional basis of granulocyte-macrophage colony stimulating factor, interleukin-3 and interleukin-5 receptor activation, basic and clinical implications.

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scholarly article

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2 November 2019

1 reference

Europe PubMed Central

The functional basis of granulocyte-macrophage colony stimulating factor, interleukin-3 and interleukin-5 receptor activation, basic and clinical implications (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10582336%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

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Joanna M Woodcock

1

1 reference

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2 November 2019

3

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2 November 2019

author name string

C J Bagley

2

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2 November 2019

publication date

1 October 1999

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2 November 2019

International Journal of Biochemistry & Cell Biology

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Europe PubMed Central

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2 November 2019

31

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2 November 2019

10

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2 November 2019

1017-1025

1 reference

Europe PubMed Central

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2 November 2019

Hematopoietic and lung abnormalities in mice with a null mutation of the common beta subunit of the receptors for granulocyte-macrophage colony-stimulating factor and interleukins 3 and 5.

1 reference

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7 January 2021

based on heuristic

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Critical proline residues of the cytoplasmic domain of the IL-5 receptor alpha chain and its function in IL-5-mediated activation of JAK kinase and STAT5.

1 reference

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7 January 2021

based on heuristic

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Specific human granulocyte-macrophage colony-stimulating factor antagonists.

1 reference

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7 January 2021

based on heuristic

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A discontinuous eight-amino acid epitope in human interleukin-3 binds the alpha-chain of its receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900084-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of receptor-binding domains on human interleukin 5 and design of an interleukin 5-derived receptor antagonist

1 reference

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7 January 2021

based on heuristic

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An interleukin 5 mutant distinguishes between two functional responses in human eosinophils.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900084-9

7 January 2021

based on heuristic

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Crucial role of the residue R280 at the F'-G' loop of the human granulocyte/macrophage colony-stimulating factor receptor alpha chain for ligand recognition

1 reference

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7 January 2021

based on heuristic

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Detailed analysis of the IL-5-IL-5R alpha interaction: characterization of crucial residues on the ligand and the receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900084-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Covalent modification of the interleukin-5 receptor by isothiazolones leads to inhibition of the binding of interleukin-5.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900084-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Human growth hormone and extracellular domain of its receptor: crystal structure of the complex

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900084-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Reciprocal inhibition of binding between interleukin 3 and granulocyte-macrophage colony-stimulating factor to human eosinophils

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900084-9

7 January 2021

based on heuristic

inferred from DOI database lookup

GM-CSF, IL-3 and IL-5: cross-competition on human haemopoietic cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900084-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Three residues in the common beta chain of the human GM-CSF, IL-3 and IL-5 receptors are essential for GM-CSF and IL-5 but not IL-3 high affinity binding and interact with Glu21 of GM-CSF

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900084-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Histidine-367 of the human common beta chain of the receptor is critical for high-affinity binding of human granulocyte-macrophage colony-stimulating factor.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900084-9

7 January 2021

based on heuristic

inferred from DOI database lookup

A single tyrosine residue in the membrane-proximal domain of the granulocyte-macrophage colony-stimulating factor, interleukin (IL)-3, and IL-5 receptor common beta-chain is necessary and sufficient for high affinity binding and signaling by all thr

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900084-9

7 January 2021

based on heuristic

inferred from DOI database lookup

JAK2 associates with the beta c chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal region

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900084-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Human interleukin-3 (IL-3) induces disulfide-linked IL-3 receptor alpha- and beta-chain heterodimerization, which is required for receptor activation but not high-affinity binding

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900084-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of a Cys motif in the common beta chain of the interleukin 3, granulocyte-macrophage colony-stimulating factor, and interleukin 5 receptors essential for disulfide-linked receptor heterodimerization and activation of all three recepto

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900084-9

7 January 2021

based on heuristic

inferred from DOI database lookup

The beta subunit of human granulocyte-macrophage colony-stimulating factor receptor forms a homodimer and is activated via association with the alpha subunit

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900084-9

7 January 2021

based on heuristic

inferred from DOI database lookup

A dominant negative granulocyte-macrophage colony-stimulating factor receptor alpha chain reveals the multimeric structure of the receptor complex

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900084-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Recombinant human granulocyte-macrophage colony-stimulating factor stimulates in vitro mature human neutrophil and eosinophil function, surface receptor expression, and survival

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900084-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Recombinant human interleukin 5 is a selective activator of human eosinophil function

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900084-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Human eosinophils have prolonged survival, enhanced functional properties, and become hypodense when exposed to human interleukin 3.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900084-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Messenger RNA expression of the cytokine gene cluster, interleukin 3 (IL-3), IL-4, IL-5, and granulocyte/macrophage colony-stimulating factor, in allergen-induced late-phase cutaneous reactions in atopic subjects

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900084-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Secretion of the eosinophil‐active cytokines interleukin‐5, granulocyte/macrophage colonystimulating factor and interleukin‐3 by bronchoalveolar lavage CD4+ and CD8+ T cell lines in atopics asthmatics, and atopic and nonatopic controls

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900084-9

7 January 2021

based on heuristic

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Peripheral blood CD4 but not CD8 t-lymphocytes in patients with exacerbation of asthma transcribe and translate messenger RNA encoding cytokines which prolong eosinophil survival in the context of a Th2-type pattern: effect of glucocorticoid therapy

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900084-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Chronic cough resembles asthma with IL-5 and granulocyte-macrophage colony-stimulating factor gene expression in bronchoalveolar cells☆☆☆★★★

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Expression of interleukin-5 and granulocyte-macrophage colony-stimulating factor in aspirin-sensitive and non-aspirin-sensitive asthmatic airways

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900084-9

7 January 2021

based on heuristic

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Curcumin inhibition of Dermatophagoides farinea-induced interleukin-5 (IL-5) and granulocyte macrophage-colony stimulating factor (GM-CSF) production by lymphocytes from bronchial asthmatics

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900084-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Stimulation of blood mononuclear cells of atopic children with the relevant allergen induces the release of eosinophil chemotaxins such as IL-3, IL-5, and GM-CSF

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S1357-2725(99)00084-9

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10582336%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10582336%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

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