(Q33790163)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28659770%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

title

Evaluation of AZD1446 as a Therapeutic in DYT1 Dystonia (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28659770%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28659770%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

Francesca Romana Rizzo

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28659770%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

David G. Standaert

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28659770%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

author name string

Chelsea N Zimmerman

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28659770%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

Karen L Eskow Jaunarajs

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28659770%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

Massimo Santoro

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28659770%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

Antonio Pisani

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28659770%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

publication date

13 June 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28659770%20AND%20SRC:MED&resulttype=core&format=json

Frontiers in Systems Neuroscience

24 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28659770%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

volume

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28659770%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

page(s)

43

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28659770%20AND%20SRC:MED&resulttype=core&format=json

Cortical Control of Striatal Dopamine Transmission via Striatal Cholinergic Interneurons

24 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468415

Population pharmacokinetics and safety of AZD1446, a neuronal nicotinic receptor agonist, administered in healthy volunteers

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468415

A randomized, double-blind, placebo-controlled crossover study of α4β 2* nicotinic acetylcholine receptor agonist AZD1446 (TC-6683) in adults with attention-deficit/hyperactivity disorder

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468415

Cholinergic dysfunction alters synaptic integration between thalamostriatal and corticostriatal inputs in DYT1 dystonia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468415

Selective activation of cholinergic interneurons enhances accumbal phasic dopamine release: setting the tone for reward processing.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468415

Discovery of 3-(5-chloro-2-furoyl)-3,7-diazabicyclo[3.3.0]octane (TC-6683, AZD1446), a novel highly selective α4β2 nicotinic acetylcholine receptor agonist for the treatment of cognitive disorders

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468415

Functional analysis of dopaminergic systems in a DYT1 knock-in mouse model of dystonia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468415

Dopamine release in the basal ganglia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468415

Developmental profile of the aberrant dopamine D2 receptor response in striatal cholinergic interneurons in DYT1 dystonia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468415

Nicotinic receptor agonists decrease L-dopa-induced dyskinesias most effectively in partially lesioned parkinsonian rats

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468415

Function of dopamine transporter is compromised in DYT1 transgenic animal model in vivo

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468415

Impairment of bidirectional synaptic plasticity in the striatum of a mouse model of DYT1 dystonia: role of endogenous acetylcholine.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468415

Opposing actions of chronic stress and chronic nicotine on striatal function in mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468415

Loss of the dystonia-associated protein torsinA selectively disrupts the neuronal nuclear envelope

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468415

Nicotine acts as a pharmacological chaperone to up-regulate human alpha4beta2 acetylcholine receptors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468415

Chronic nicotine exposure upregulates nicotinic receptors by a novel mechanism

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468415

Alternate stoichiometries of alpha4beta2 nicotinic acetylcholine receptors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468415

Desensitization of neuronal nicotinic receptors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468415

Endogenous nicotinic cholinergic activity regulates dopamine release in the striatum

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468415

Alpha3, beta2, and beta4 form heterotrimeric neuronal nicotinic acetylcholine receptors in Xenopus oocytes.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468415

The early-onset torsion dystonia gene (DYT1) encodes an ATP-binding protein

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468415

Presynaptic regulation of neurotransmitter release in the brain: Facts and hypothesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468415

Bregma, lambda and the interaural midpoint in stereotaxic surgery with rats of different sex, strain and weight

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468415

Innervation of substantia nigra neurons by cholinergic afferents from pedunculopontine nucleus in the rat: neuroanatomical and electrophysiological evidence.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468415

Morphology and electrophysiological properties of immunocytochemically identified rat dopamine neurons recorded in vitro.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468415

Distribution of alpha 2, alpha 3, alpha 4, and beta 2 neuronal nicotinic receptor subunit mRNAs in the central nervous system: a hybridization histochemical study in the rat.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468415

Involvement of cholinergic presynaptic receptors of nicotinic and muscarinic types in the control of the spontaneous release of dopamine from striatal dopaminergic terminals in the rat.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468415

"Complex" dystonia is not a category in the new 2013 consensus classification.

28 July 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNSYS.2017.00043

Dopamine release is impaired in a mouse model of DYT1 dystonia

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNSYS.2017.00043

Continuous and intermittent nicotine treatment reduces L-3,4-dihydroxyphenylalanine (L-DOPA)-induced dyskinesias in a rat model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNSYS.2017.00043

Anticholinergic drugs rescue synaptic plasticity in DYT1 dystonia: role of M1 muscarinic receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNSYS.2017.00043

Regional specificity of synaptic plasticity deficits in a knock-in mouse model of DYT1 dystonia.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNSYS.2017.00043

Involvement of alpha7- and alpha4beta2-type postsynaptic nicotinic acetylcholine receptors in nicotine-induced excitation of dopaminergic neurons in the substantia nigra: a patch clamp and single-cell PCR study using acutely dissociated nigral neuro

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNSYS.2017.00043

Excitation of rat striatal large neurons by dopamine and/or glutamate released from nerve terminals via presynaptic nicotinic receptor (A4beta2 type) stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNSYS.2017.00043

Nicotine reduces levodopa-induced dyskinesias in lesioned monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNSYS.2017.00043

Nicotine amplifies reward-related dopamine signals in striatum

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNSYS.2017.00043

Nicotine upregulates its own receptors through enhanced intracellular maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNSYS.2017.00043

Striatal dopamine release is triggered by synchronized activity in cholinergic interneurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNSYS.2017.00043

Chronic exposure to nicotine upregulates the human (alpha)4((beta)2 nicotinic acetylcholine receptor function.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468415

Upregulation of surface alpha4beta2 nicotinic receptors is initiated by receptor desensitization after chronic exposure to nicotine.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468415

A semiautomated analysis method for catecholamines, indoleamines, and some prominent metabolites in microdissected regions of the nervous system: an isocratic HPLC technique employing coulometric detection and minimal sample preparation.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468415

Medical treatment of dystonia

30 October 2018

1 reference

12 December 2020

Treatment of spastic dystonia with transdermal nicotine

1 reference

12 December 2020

Properties of the hyperpolarization-activated cation current Ih in rat midbrain dopaminergic neurons

1 reference

12 December 2020

Generation of a novel rodent model for DYT1 dystonia

1 reference

12 December 2020

Two cell types in rat substantia nigra zona compacta distinguished by membrane properties and the actions of dopamine and opioids

1 reference

12 December 2020

Identifiers

DOI

10.3389/FNSYS.2017.00043

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28659770%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28659770%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

1 reference