(Q33792630)

29 July 2017

title

DNA breaks at fragile sites generate oncogenic RET/PTC rearrangements in human thyroid cells (English)

1 reference

29 July 2017

M Gandhi

1

1 reference

29 July 2017

L W Dillon

2

1 reference

29 July 2017

S Pramanik

3

1 reference

29 July 2017

Y E Nikiforov

4

1 reference

29 July 2017

Y-H Wang

5

1 reference

29 July 2017

language of work or name

English

0 references

publication date

25 January 2010

1 reference

29 July 2017

1 reference

29 July 2017

volume

29

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29 July 2017

issue

15

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29 July 2017

page(s)

2272-2280

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Thyroid carcinoma: molecular pathways and therapeutic targets

29 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855398

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28 July 2018

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Replication stress induces tumor-like microdeletions in FHIT/FRA3B

28 July 2018

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Regulation of DNA double-strand break repair pathway choice

28 July 2018

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Molecular genetics of thyroid cancer: implications for diagnosis, treatment and prognosis

28 July 2018

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The role of chromosomal alterations in human cancer development

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855398

An AT-rich sequence in human common fragile site FRA16D causes fork stalling and chromosome breakage in S. cerevisiae

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855398

28 July 2018

Chromosome fragile sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855398

Common fragile sites as targets for chromosome rearrangements

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855398

The role of late/slow replication of the FRA16D in common fragile site induction

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855398

Molecular basis for expression of common and rare fragile sites

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855398

Genetic alterations in cancer as a result of breakage at fragile sites

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855398

ATR Regulates Fragile Site Stability

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855398

Breaksite batch mapping, a rapid method for assay and identification of DNA breaksites in mammalian cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855398

Replication delay along FRA7H, a common fragile site on human chromosome 7, leads to chromosomal instability

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855398

Allele-specific late replication and fragility of the most active common fragile site, FRA3B.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855398

A new role for hypoxia in tumor progression: induction of fragile site triggering genomic rearrangements and formation of complex DMs and HSRs

28 July 2018

1 reference

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ret rearrangements in Japanese pediatric and adult papillary thyroid cancers.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855398

FRA10B structure reveals common elements in repeat expansion and chromosomal fragile site genesis.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855398

Molecular characterization of a common fragile site (FRA7H) on human chromosome 7 by the cloning of a simian virus 40 integration site.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855398

Comparison of the breakpoint regions of ELE1 and RET genes involved in the generation of RET/PTC3 oncogene in sporadic and in radiation-associated papillary thyroid carcinomas.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855398

A variable domain of delayed replication in FRAXA fragile X chromosomes: X inactivation-like spread of late replication

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855398

Oncogenic rearrangements of the RET proto-oncogene in papillary thyroid carcinomas from children exposed to the Chernobyl nuclear accident

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855398

CGG repeats associated with DNA instability and chromosome fragility form structures that block DNA synthesis in vitro

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855398

Constitutive fragile sites and cancer.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855398

Induction of sister chromatid exchanges at common fragile sites

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855398

Chromosome breakage and recombination at fragile sites

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855398

Fibroblast-specific common fragile sites induced by aphidicolin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855398

Chromosomal fragile sites

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855398

Chromosome 3p14 homozygous deletions and sequence analysis of FRA3B.

28 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.502

Over half of breakpoints in gene pairs involved in cancer-specific recurrent translocations are mapped to human chromosomal fragile sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.502

Chromosomal instability at common fragile sites in Seckel syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.502

Trinucleotide repeats that expand in human disease form hairpin structures in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.502

21 January 2018

Common fragile sites.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.502

RET rearrangements in radiation-induced papillary thyroid carcinomas: high prevalence of topoisomerase I sites at breakpoints and microhomology-mediated end joining in ELE1 and RET chimeric genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.502

Replication timing of two human common fragile sites: FRA1H and FRA2G.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.502

RET/PTC activation in papillary thyroid carcinoma: European Journal of Endocrinology Prize Lecture

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.502

Identification of unstable sequences within the common fragile site at 3p14.2: implications for the mechanism of deletions within fragile histidine triad gene/common fragile site at 3p14.2 in tumors

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855398

Dose-dependent generation of RET/PTC in human thyroid cells after in vitro exposure to gamma-radiation: a model of carcinogenic chromosomal rearrangement induced by ionizing radiation

30 October 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.502

BRAF copy number gains in thyroid tumors detected by fluorescence in situ hybridization

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.502

Analysis of replication timing at the FRA10B and FRA16B fragile site loci

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.502

A role for common fragile site induction in amplification of human oncogenes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.502

Aphidicolin-sensitive specific common fragile sites: a biomarker of exposure to pesticides

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.502

Chromosomal breakpoint positions suggest a direct role for radiation in inducing illegitimate recombination between the ELE1 and RET genes in radiation-induced thyroid carcinomas

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.502

Trinucleotide repeats affect DNA replication in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.502

Breakpoint characterization of the ret/PTC oncogene in human papillary thyroid carcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.502

New classes of common fragile sites induced by 5-azacytidine and bromodeoxyuridine

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.502

Synergistic effect of aphidicolin and ethanol on the induction of common fragile sites

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20101222

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Distinct pattern of ret oncogene rearrangements in morphological variants of radiation-induced and sporadic thyroid papillary carcinomas in children.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20101222

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The ret/PTC mutations are common in sporadic papillary thyroid carcinoma of children and young adults

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20101222

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2009.502

1 reference

Dimensions Publication ID

29 July 2017

0 references

1 reference

29 July 2017

1 reference