(Q33795294)

English

Direct observations of amyloid β self-assembly in live cells provide insights into differences in the kinetics of Aβ(1-40) and Aβ(1-42) aggregation.

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scholarly article

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19 March 2020

Direct observations of amyloid β self-assembly in live cells provide insights into differences in the kinetics of Aβ(1-40) and Aβ(1-42) aggregation (English)

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19 March 2020

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Elin K. Esbjörner

1

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19 March 2020

Clemens F Kaminski

7

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19 March 2020

author name string

Fiona Chan

2

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19 March 2020

Eric Rees

3

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19 March 2020

Miklos Erdelyi

4

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19 March 2020

Leila M Luheshi

5

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19 March 2020

Carlos W Bertoncini

6

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19 March 2020

Gabriele S Kaminski Schierle

9

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19 March 2020

Christopher M Dobson

8

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19 March 2020

publication date

22 May 2014

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19 March 2020

Chemistry and Biology

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19 March 2020

21

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19 March 2020

6

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19 March 2020

732-742

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19 March 2020

describes a project that uses

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11 June 2022

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Direct observation of heterogeneous amyloid fibril growth kinetics via two-color super-resolution microscopy

1 reference

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Extracellular monomeric tau protein is sufficient to initiate the spread of tau protein pathology

1 reference

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28 July 2018

Proliferation of amyloid-β42 aggregates occurs through a secondary nucleation mechanism

1 reference

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28 July 2018

Protein amyloids develop an intrinsic fluorescence signature during aggregation

1 reference

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28 July 2018

NIH Image to ImageJ: 25 years of image analysis

1 reference

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28 July 2018

From macroscopic measurements to microscopic mechanisms of protein aggregation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067742

28 July 2018

The extracellular chaperone clusterin sequesters oligomeric forms of the amyloid-β(1-40) peptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067742

28 July 2018

High-resolution 3D reconstruction reveals intra-synaptic amyloid fibrils.

1 reference

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28 July 2018

Amyloid-β forms fibrils by nucleated conformational conversion of oligomers

1 reference

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28 July 2018

In situ measurements of the formation and morphology of intracellular β-amyloid fibrils by super-resolution fluorescence imaging

1 reference

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28 July 2018

A FRET sensor for non-invasive imaging of amyloid formation in vivo

1 reference

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28 July 2018

Mechanisms of quenching of Alexa fluorophores by natural amino acids

1 reference

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28 July 2018

Mechanism of amyloid plaque formation suggests an intracellular basis of Abeta pathogenicity

1 reference

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28 July 2018

A causative link between the structure of aberrant protein oligomers and their toxicity.

1 reference

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28 July 2018

Real-time computation of subdiffraction-resolution fluorescence images

1 reference

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28 July 2018

Amyloid seeds formed by cellular uptake, concentration, and aggregation of the amyloid-beta peptide

1 reference

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28 July 2018

Misfolded proteins partition between two distinct quality control compartments

1 reference

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28 July 2018

Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067742

28 July 2018

Fluorescence imaging of amyloid formation in living cells by a functional, tetracysteine-tagged alpha-synuclein

1 reference

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28 July 2018

Detection of novel intracellular alpha-synuclein oligomeric species by fluorescence lifetime imaging

1 reference

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28 July 2018

Protein misfolding, functional amyloid, and human disease

1 reference

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28 July 2018

Precise nanometer localization analysis for individual fluorescent probes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067742

28 July 2018

Acidic pH promotes the formation of toxic fibrils from beta-amyloid peptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067742

28 July 2018

Intraneuronal Abeta42 accumulation in human brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067742

28 July 2018

On the nucleation and growth of amyloid beta-protein fibrils: detection of nuclei and quantitation of rate constants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067742

28 July 2018

The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease

1 reference

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28 July 2018

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

1 reference

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28 July 2018

Amyloid plaque core protein in Alzheimer disease and Down syndrome

1 reference

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28 July 2018

Amyloid deposition as the central event in the aetiology of Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067742

28 July 2018

Assembly and aggregation properties of synthetic Alzheimer's A4/beta amyloid peptide analogs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067742

28 July 2018

Intracellular accumulation and resistance to degradation of the Alzheimer amyloid A4/beta protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067742

28 July 2018

A label-free, quantitative assay of amyloid fibril growth based on intrinsic fluorescence

1 reference

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30 October 2018

Selenium-enhanced electron microscopic imaging of different aggregate forms of a segment of the amyloid β peptide in cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067742

30 October 2018

Fluorescence lifetime dynamics of enhanced green fluorescent protein in protein aggregates with expanded polyglutamine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067742

30 October 2018

Highly inclined thin illumination enables clear single-molecule imaging in cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067742

30 October 2018

Abeta peptides can enter the brain through a defective blood-brain barrier and bind selectively to neurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067742

30 October 2018

Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice

1 reference

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30 October 2018

Oligomerization of Alzheimer's beta-amyloid within processes and synapses of cultured neurons and brain.

1 reference

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30 October 2018

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1 reference

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30 October 2018

Preferential adsorption, internalization and resistance to degradation of the major isoform of the Alzheimer's amyloid peptide, A beta 1-42, in differentiated PC12 cells

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The oligomerization of amyloid beta-protein begins intracellularly in cells derived from human brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/24856820

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.CHEMBIOL.2014.03.014

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19 March 2020

1 reference

Europe PubMed Central

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19 March 2020

1 reference

Europe PubMed Central

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19 March 2020

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