(Q33800161)

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Add-on prolonged-release melatonin for cognitive function and sleep in mild to moderate Alzheimer's disease: a 6-month, randomized, placebo-controlled, multicenter trial

scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Add-on prolonged-release melatonin for cognitive function and sleep in mild to moderate Alzheimer's disease: a 6-month, randomized, placebo-controlled, multicenter trial (English)

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

0 references

multicenter clinical trial

0 references

Alzheimer's disease

0 references

0 references

author name string

Alan G Wade

1

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Mildred Farmer

2

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Gil Harari

3

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Naama Fund

4

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Moshe Laudon

5

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Tali Nir

6

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Anat Frydman-Marom

7

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Nava Zisapel

8

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

language of work or name

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publication date

18 June 2014

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Clinical Interventions in Aging

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

9

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

947-961

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

copyright license

Creative Commons Attribution-NonCommercial 3.0 Unported

1 June 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Sleep and Alzheimer disease pathology--a bidirectional relationship

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4069047

4 July 2018

Self-reported sleep and β-amyloid deposition in community-dwelling older adults

1 reference

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4 July 2018

Modification of the relationship of the apolipoprotein E ε4 allele to the risk of Alzheimer disease and neurofibrillary tangle density by sleep

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4069047

4 July 2018

Sleep drives metabolite clearance from the adult brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4069047

4 July 2018

Synthesis and comparison of the meta-analyses evaluating the efficacy of memantine in moderate to severe stages of Alzheimer's disease

1 reference

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4 July 2018

Sleep quality and preclinical Alzheimer disease

1 reference

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4 July 2018

Therapeutic application of melatonin in mild cognitive impairment.

1 reference

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4 July 2018

Melatonin for sleep problems in children with neurodevelopmental disorders: randomised double masked placebo controlled trial

1 reference

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4 July 2018

Benzodiazepine use and risk of dementia: prospective population based study

1 reference

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4 July 2018

Prolonged-release formulation of melatonin (Circadin) for the treatment of insomnia

1 reference

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4 July 2018

Effects of a diet integration with an oily emulsion of DHA-phospholipids containing melatonin and tryptophan in elderly patients suffering from mild cognitive impairment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4069047

4 July 2018

Melatonin plus physical exercise are highly neuroprotective in the 3xTg-AD mouse.

1 reference

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4 July 2018

What is the clinically relevant change on the ADAS-Cog?

1 reference

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4 July 2018

Memory disorders associated with consumption of drugs: updating through a case/noncase study in the French PharmacoVigilance Database

1 reference

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4 July 2018

Effects of the use of hypnotics on cognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4069047

4 July 2018

Melatonin and its agonist ramelteon in Alzheimer's disease: possible therapeutic value

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4069047

4 July 2018

Do sleep complaints contribute to age-related cognitive decline?

1 reference

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4 July 2018

Determining the minimum clinically important differences for outcomes in the DOMINO trial.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4069047

4 July 2018

Is modulation of nicotinic acetylcholine receptors by melatonin relevant for therapy with cholinergic drugs?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4069047

4 July 2018

Alzheimer's Disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4069047

4 July 2018

The association between dementia and long-term use of benzodiazepine in the elderly: nested case-control study using claims data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4069047

4 July 2018

Melatonin fails to improve sleep or agitation in double-blind randomized placebo-controlled trial of institutionalized patients with Alzheimer disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4069047

4 July 2018

Clinical trial design issues in mild to moderate Alzheimer disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4069047

4 July 2018

Efficacy and safety of donepezil, galantamine, and rivastigmine for the treatment of Alzheimer's disease: a systematic review and meta-analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4069047

4 July 2018

The impact of analytic method on interpretation of outcomes in longitudinal clinical trials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4069047

4 July 2018

Effect of bright light and melatonin on cognitive and noncognitive function in elderly residents of group care facilities: a randomized controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4069047

4 July 2018

Melatonin and bright-light treatment for rest-activity disruption in institutionalized patients with Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4069047

4 July 2018

Efficacy of prolonged release melatonin in insomnia patients aged 55–80 years: quality of sleep and next-day alertness outcomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4069047

4 July 2018

Impaired declarative memory consolidation during sleep in patients with primary insomnia: Influence of sleep architecture and nocturnal cortisol release.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4069047

4 July 2018

A multicenter, placebo-controlled trial of melatonin for sleep disturbance in Alzheimer's disease.

1 reference

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4 July 2018

The Sleep Disorders Inventory: an instrument for studies of sleep disturbance in persons with Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4069047

4 July 2018

Measuring well-being rather than the absence of distress symptoms: a comparison of the SF-36 Mental Health subscale and the WHO-Five Well-Being Scale.

1 reference

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4 July 2018

The role of sleep in learning and memory

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4069047

4 July 2018

Clinical trials of controlled-release melatonin in children with sleep-wake cycle disorders

1 reference

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4 July 2018

Melatonin secretion rhythm disorders in patients with senile dementia of Alzheimer's type with disturbed sleep-waking.

1 reference

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4 July 2018

A 24-week, double-blind, placebo-controlled trial of donepezil in patients with Alzheimer's disease. Donepezil Study Group

1 reference

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4 July 2018

Development of cognitive instruments for use in clinical trials of antidementia drugs: additions to the Alzheimer's Disease Assessment Scale that broaden its scope. The Alzheimer's Disease Cooperative Study.

1 reference

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4 July 2018

Neuroprotective effects of melatonin

1 reference

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4 July 2018

The Neuropsychiatric Inventory: comprehensive assessment of psychopathology in dementia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4069047

4 July 2018

Improvement of sleep quality in elderly people by controlled-release melatonin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4069047

4 July 2018

The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4069047

4 July 2018

Sleep Problems and Institutionalization of the Elderly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4069047

4 July 2018

Concentrations of serotonin and its related substances in the cerebrospinal fluid in patients with Alzheimer type dementia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4069047

4 July 2018

“Mini-mental state”

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4069047

4 July 2018

Sleep evaluation by actigraphy for patients with Alzheimer disease--reply

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4069047

30 October 2018

Sleep evaluation by actigraphy for patients with Alzheimer disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4069047

30 October 2018

The effect of self-reported habitual sleep quality and sleep length on autobiographical memory.

1 reference

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30 October 2018

Poor sleep quality impairs cognitive performance in older adults

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4069047

30 October 2018

Effects of prolonged-release melatonin and zolpidem on postural stability in older adults

1 reference

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30 October 2018

Prolonged-release melatonin for children with neurodevelopmental disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4069047

30 October 2018

Prolonged release melatonin in the treatment of primary insomnia: evaluation of the age cut-off for short- and long-term response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4069047

30 October 2018

Low sleep efficiency in patients with cognitive impairment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4069047

30 October 2018

The effect of prolonged-release melatonin on sleep measures and psychomotor performance in elderly patients with insomnia.

1 reference

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30 October 2018

Highway driving performance and cognitive functioning the morning after bedtime and middle-of-the-night use of gaboxadol, zopiclone and zolpidem.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4069047

30 October 2018

The ADAS-cog and clinically meaningful change in the VISTA clinical trial of galantamine for Alzheimer's disease.

1 reference

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30 October 2018

Effects of prolonged-release melatonin, zolpidem, and their combination on psychomotor functions, memory recall, and driving skills in healthy middle aged and elderly volunteers

1 reference

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A five-point change in Modified Mini-Mental State Examination was clinically meaningful in community-dwelling elderly people.

1 reference

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Melatonin and the human hippocampus, a time dependent interplay

1 reference

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30 October 2018

Actigraphy in agitated patients with dementia. Monitoring treatment outcomes.

1 reference

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30 October 2018

Double blind study of melatonin effects on the sleep-wake rhythm, cognitive and non-cognitive functions in Alzheimer type dementia

1 reference

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30 October 2018

Double blind randomised placebo controlled trial of low dose melatonin for sleep disorders in dementia

1 reference

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30 October 2018

Melatonin treatment stabilizes chronobiologic and cognitive symptoms in Alzheimer's disease.

1 reference

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30 October 2018

Monozygotic twins with Alzheimer's disease treated with melatonin: Case report

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4069047

30 October 2018

Prolonged-release melatonin for the treatment of insomnia in patients over 55 years

1 reference

https://pubmed.ncbi.nlm.nih.gov/24971004

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessment of older people: self-maintaining and instrumental activities of daily living

1 reference

https://pubmed.ncbi.nlm.nih.gov/24971004

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2147/CIA.S65625

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

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