(Q33804496)

29 July 2017

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title

Basic mechanisms of gabitril (tiagabine) and future potential developments (English)

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29 July 2017

Meldrum BS

1

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29 July 2017

Chapman AG

series ordinal

2

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29 July 2017

publication date

1 January 1999

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29 July 2017

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29 July 2017

volume

40 Suppl 9

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29 July 2017

page(s)

S2-6

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Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors

29 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1999.TB02087.X

GABA transporter heterogeneity: pharmacology and cellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1999.TB02087.X

Identification and characterization of the vesicular GABA transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1999.TB02087.X

Cloning of a functional vesicular GABA and glycine transporter by screening of genome databases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1999.TB02087.X

Immunoreactivity for the GABA transporter-1 and GABA transporter-3 is restricted to astrocytes in the rat thalamus. A light and electron-microscopic immunolocalization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1999.TB02087.X

Neuronal and glial localization of two GABA transporters (GAT1 and GAT3) in the rat cerebellum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1999.TB02087.X

Immunocytochemical localization of three subtypes of GABA transporter in rat retina

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1999.TB02087.X

Embryonic and postnatal expression of four gamma-aminobutyric acid transporter mRNAs in the mouse brain and leptomeninges.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1999.TB02087.X

Immunoreactivity for GABA plasma membrane transporter, GAT-1, in the developing rat cerebral cortex: transient presence in the somata of neocortical and hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1999.TB02087.X

Reduction of GABA and glutamate transporter messenger RNAs in the severe-seizure genetically epilepsy-prone rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1999.TB02087.X

Time-dependent and regional expression of GABA transporter mRNAs following amygdala-kindled seizures in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1999.TB02087.X

Influence of inhibitors of the high affinity GABA uptake on seizure thresholds in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1999.TB02087.X

Orally active and potent inhibitors of gamma-aminobutyric acid uptake

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1999.TB02087.X

The synthesis of novel GABA uptake inhibitors. 1. Elucidation of the structure-activity studies leading to the choice of (R)-1-[4,4-bis(3-methyl-2-thienyl)-3-butenyl]-3-piperidinecarboxylic acid (tiagabine) as an anticonvulsant drug candidate

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1999.TB02087.X

NNC-711, a novel potent and selective gamma-aminobutyric acid uptake inhibitor: pharmacological characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1999.TB02087.X

Characterization of tiagabine (NO-328), a new potent and selective GABA uptake inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1999.TB02087.X

Treatment of experimental status epilepticus with the GABA uptake inhibitor, tiagabine

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1999.TB02087.X

Tiagabine prevents seizures, neuronal damage and memory impairment in experimental status epilepticus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1999.TB02087.X

Tiagabine exerts an anti-epileptogenic effect in amygdala kindling epileptogenesis in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1999.TB02087.X

The gamma-aminobutyric acid (GABA) uptake inhibitor, tiagabine, increases extracellular brain levels of GABA in awake rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1999.TB02087.X

Comparison of the effect of the GABA uptake blockers, tiagabine and nipecotic acid, on inhibitory synaptic efficacy in hippocampal CA1 neurones

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1999.TB02087.X

Tiagabine, SK&F 89976-A, CI-966, and NNC-711 are selective for the cloned GABA transporter GAT-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1999.TB02087.X

Anticonvulsant properties of two GABA uptake inhibitors NNC 05-2045 and NNC 05-2090, not acting preferentially on GAT-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1999.TB02087.X

Adjunctive treatment of partial seizures with tiagabine: a placebo-controlled trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1999.TB02087.X

Tiagabine for complex partial seizures: a randomized, add-on, dose-response trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1999.TB02087.X

Effect of the GABA uptake inhibitor tiagabine on sleep and EEG power spectra in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1999.TB02087.X

Hippocampal GABA transporter function in temporal-lobe epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1999.TB02087.X

10.1111/J.1528-1157.1999.TB02087.X

21 January 2018

Identifiers

DOI

1 reference

29 July 2017

1 reference