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Molecular virology of the hepatitis C virus.
scientific article
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
10622560
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10622560%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
review article
1 reference
stated in
Europe PubMed Central
title
Molecular virology of the hepatitis C virus
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
10622560
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10622560%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
main subject
virology
0 references
Hepatitis C virus
1 reference
based on heuristic
inferred from title
hepatitis C
1 reference
based on heuristic
inferred from title
author
Raffaele De Francesco
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
10622560
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10622560%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
author name string
De Francesco R
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
10622560
retrieved
29 July 2017
publication date
1 January 1999
1 reference
stated in
Europe PubMed Central
PubMed ID
10622560
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10622560%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
published in
Journal of Hepatology
1 reference
stated in
Europe PubMed Central
PubMed ID
10622560
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10622560%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
volume
31 Suppl 1
1 reference
stated in
Europe PubMed Central
PubMed ID
10622560
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10622560%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
page(s)
47-53
1 reference
stated in
Europe PubMed Central
PubMed ID
10622560
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10622560%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
cites work
Structure and function of the hepatitis C virus internal ribosome entry site
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gene mapping of the putative structural region of the hepatitis C virus genome by in vitro processing analysis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Biosynthesis and biochemical properties of the hepatitis C virus core protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A second hepatitis C virus-encoded proteinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nonstructural protein 3 of the hepatitis C virus encodes a serine-type proteinase required for cleavage at the NS3/4 and NS4/5 junctions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Production of nonstructural proteins of hepatitis C virus requires a putative viral protease encoded by NS3.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of NS3-mediated processing of the hepatitis C virus non-structural region in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel sequence found at the 3' terminus of hepatitis C virus genome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a highly conserved sequence element at the 3' terminus of hepatitis C virus genome RNA
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Specific interaction of polypyrimidine tract-binding protein with the extreme 3'-terminal structure of the hepatitis C virus genome, the 3'X
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Detection of Cellular Proteins and Viral Core Protein Interacting with the 5' Untranslated Region of Hepatitis C Virus RNA.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Homotypic interaction and multimerization of hepatitis C virus core protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of hepatitis C virus core protein interaction domains
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hepatitis C virus core protein inhibits human immunodeficiency virus type 1 replication
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcriptional regulation of cellular and viral promoters by the hepatitis C virus core protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcriptional repression of p53 promoter by hepatitis C virus core protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hepatitis C virus core protein represses p21WAF1/Cip1/Sid1 promoter activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hepatitis C virus core protein cooperates with ras and transforms primary rat embryo fibroblasts to tumorigenic phenotype
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The core protein of hepatitis C virus induces hepatocellular carcinoma in transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hepatitis C virus core protein inhibits Fas- and tumor necrosis factor alpha-mediated apoptosis via NF-kappaB activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Direct interaction of hepatitis C virus core protein with the cellular lymphotoxin-beta receptor modulates the signal pathway of the lymphotoxin-beta receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hepatitis C virus core protein interacts with the cytoplasmic tail of lymphotoxin-beta receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression and characterization of glycoprotein gp35 of hepatitis C virus using recombinant vaccinia virus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of hepatitis C virus envelope proteins in transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of hepatitis C virus capsid, E1, and E2/NS1 proteins expressed in insect cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of processed envelope protein of hepatitis C virus in mammalian and insect cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Processing of E1 and E2 glycoproteins of hepatitis C virus expressed in mammalian and insect cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of the hepatitis C virus E2/NS1 gene product expressed in mammalian cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Virion-like structures in HeLa G cells transfected with the full-length sequence of the hepatitis C virus genome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hepatitis C virus structural proteins assemble into viruslike particles in insect cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypervariable regions in the putative glycoprotein of hepatitis C virus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Variable and hypervariable domains are found in the regions of HCV corresponding to the flavivirus envelope and NS1 proteins and the pestivirus envelope glycoproteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Binding of hepatitis C virus to CD81
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Kinetic and structural analyses of hepatitis C virus polyprotein processing
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An amino-terminal domain of the hepatitis C virus NS3 protease is essential for interaction with NS4A
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of the domain required for trans-cleavage activity of hepatitis C viral serine proteinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of the protease domain in NS3 of hepatitis C virus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Specificity of the hepatitis C virus NS3 serine protease: effects of substitutions at the 3/4A, 4A/4B, 4B/5A, and 5A/5B cleavage sites on polyprotein processing
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hepatitis C virus NS3 serine proteinase: trans-cleavage requirements and processing kinetics
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The hepatitis C virus NS3 serine proteinase and NS4A cofactor: establishment of a cell-free trans-processing assay
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular model of the specificity pocket of the hepatitis C virus protease: implications for substrate recognition.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hepatitis C virus-encoded nonstructural protein NS4A has versatile functions in viral protein processing
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A central hydrophobic domain of the hepatitis C virus NS4A protein is necessary and sufficient for the activation of the NS3 protease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In vitro studies on the activation of the hepatitis C virus NS3 proteinase by the NS4A cofactor.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Enhancement of hepatitis C virus NS3 proteinase activity by association with NS4A-specific synthetic peptides: identification of sequence and critical residues of NS4A for the cofactor activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The crystal structure of hepatitis C virus NS3 proteinase reveals a trypsin-like fold and a structural zinc binding site
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A zinc binding site in viral serine proteinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Spectroscopic characterization of rhinoviral protease 2A: Zn is essential for the structural integrity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Helicases: amino acid sequence comparisons and structure-function relationships
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A steady-state and pre-steady-state kinetic analysis of the NTPase activity associated with the hepatitis C virus NS3 helicase domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of RNA binding activity and RNA helicase activity of the hepatitis C virus NS3 protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression, isolation, and characterization of the hepatitis C virus ATPase/RNA helicase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
C-terminal domain of the hepatitis C virus NS3 protein contains an RNA helicase activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The helicase activity associated with hepatitis C virus nonstructural protein 3 (NS3)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA helicase activity of the hepatitis C virus nonstructural protein 3.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A point mutation abolishes the helicase but not the nucleoside triphosphatase activity of hepatitis C virus NS3 protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutational analysis of the hepatitis C virus RNA helicase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Non-structural protein 3 of hepatitis C virus inhibits phosphorylation mediated by cAMP-dependent protein kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nonstructural protein 3 of hepatitis C virus blocks the distribution of the free catalytic subunit of cyclic AMP-dependent protein kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Production of two phosphoproteins from the NS5A region of the hepatitis C viral genome.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Comparison of full-length sequences of interferon-sensitive and resistant hepatitis C virus 1b. Sensitivity to interferon is conferred by amino acid substitutions in the NS5A region
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in the nonstructural protein 5A gene and response to interferon in patients with chronic hepatitis C virus 1b infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pretreatment virus load and multiple amino acid substitutions in the interferon sensitivity-determining region predict the outcome of interferon treatment in patients with chronic genotype 1b hepatitis C virus infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of genotypes and amino acid residues 2209 to 2248 of the NS5A region of hepatitis C virus in relation to the response to interferon-beta therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence that hepatitis C virus resistance to interferon is mediated through repression of the PKR protein kinase by the nonstructural 5A protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Control of PKR protein kinase by hepatitis C virus nonstructural 5A protein: molecular mechanisms of kinase regulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression, purification, and partial characterization of HCV RNA polymerase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980374-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0168-8278(99)80374-2
1 reference
stated in
Europe PubMed Central
PubMed ID
10622560
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10622560%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
PubMed ID
10622560
1 reference
stated in
Europe PubMed Central
PubMed ID
10622560
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10622560%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
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