(Q33809839)

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Integrated analysis of preclinical data to support the design of the first in man study of LY2181308, a second generation antisense oligonucleotide

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scholarly article

1 reference

Europe PubMed Central

29 July 2017

Integrated analysis of preclinical data to support the design of the first in man study of LY2181308, a second generation antisense oligonucleotide (English)

1 reference

Europe PubMed Central

29 July 2017

author name string

Sophie Callies

1

1 reference

Europe PubMed Central

29 July 2017

Valérie André

2

1 reference

Europe PubMed Central

29 July 2017

Bharvin Patel

3

1 reference

Europe PubMed Central

29 July 2017

David Waters

4

1 reference

Europe PubMed Central

29 July 2017

Paul Francis

5

1 reference

Europe PubMed Central

29 July 2017

Michael Burgess

6

1 reference

Europe PubMed Central

29 July 2017

Michael Lahn

7

1 reference

Europe PubMed Central

29 July 2017

language of work or name

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publication date

1 March 2011

1 reference

Europe PubMed Central

29 July 2017

British Journal of Clinical Pharmacology

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Europe PubMed Central

29 July 2017

71

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29 July 2017

3

1 reference

Europe PubMed Central

29 July 2017

416-428

1 reference

Europe PubMed Central

29 July 2017

Antisense inhibition of survivin expression as a cancer therapeutic

1 reference

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4 July 2018

Phase I trial of AEG35156 administered as a 7-day and 3-day continuous intravenous infusion in patients with advanced refractory cancer

1 reference

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Flat-fixed dosing versus body surface area based dosing of anticancer drugs in adults: does it make a difference?

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Role of the Survivin gene in pathophysiology

1 reference

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Model-based drug development: the road to quantitative pharmacology

1 reference

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4 July 2018

What's wrong with our cancer models?

1 reference

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4 July 2018

Toxicology of antisense therapeutics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045551

4 July 2018

Predictive pharmacokinetic-pharmacodynamic modeling of tumor growth kinetics in xenograft models after administration of anticancer agents

1 reference

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4 July 2018

Validating survivin as a cancer therapeutic target

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045551

4 July 2018

Relationships between drug activity in NCI preclinical in vitro and in vivo models and early clinical trials

1 reference

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4 July 2018

Population pharmacokinetics. A regulatory perspective.

1 reference

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4 July 2018

The population approach to pharmacokinetic data analysis: rationale and standard data analysis methods

1 reference

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4 July 2018

Pharmacokinetics of a tumor necrosis factor-alpha phosphorothioate 2'-O-(2-methoxyethyl) modified antisense oligonucleotide: comparison across species

1 reference

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21 January 2018

Evaluation of the branched-chain DNA assay for measurement of RNA in formalin-fixed tissues

1 reference

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21 January 2018

Interaction between structural, statistical, and covariate models in population pharmacokinetic analysis.

1 reference

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21 January 2018

Comparison of pharmacokinetics and tissue disposition of an antisense phosphorothioate oligonucleotide targeting human Ha-ras mRNA in mouse and monkey.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2010.03836.X

21 January 2018

A phase I pharmacokinetic and pharmacodynamic study of OGX-011, a 2'-methoxyethyl antisense oligonucleotide to clusterin, in patients with localized prostate cancer

1 reference

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21 January 2018

The evaluation of estrogen receptor in primary breast carcinoma by computer-assisted image analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21284701

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of long-term administration of the survivin mRNA-targeted antisense oligonucleotide LY2181308 with reversible kidney injury in a patient with metastatic melanoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/21284701

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1365-2125.2010.03836.X

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

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