(Q33812164)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24934217%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

title

Gain and loss of function of P2X7 receptors: mechanisms, pharmacology and relevance to diabetic neuropathic pain (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24934217%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

0 references

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24934217%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Emily Langron

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24934217%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

author name string

Daniel Ursu

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24934217%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Cara Ruble

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24934217%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Leanne Munsie

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24934217%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Wei Zou

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24934217%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Bonnie Fijal

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24934217%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Yue-Wei Qian

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24934217%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Terry A McNearney

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24934217%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Adrian Mogg

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24934217%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Olivera Grubisha

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24934217%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Kalpana Merchant

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24934217%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Emanuele Sher

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24934217%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

publication date

16 June 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24934217%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24934217%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

volume

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24934217%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

page(s)

37

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24934217%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1186/1744-8069-10-37

20 March 2020

exact match

0 references

cites work

Sex differences in pain: a brief review of clinical and experimental findings

1 reference

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Motor neuron dysfunction in a mouse model of ALS: gender-dependent effect of P2X7 antagonism.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072620

P2X receptors as drug targets

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072620

The P2X(7) loss-of-function Glu496Ala polymorphism affects ex vivo cytokine release and protects against the cytotoxic effects of high ATP-levels

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072620

Association of P2X7 receptor polymorphisms with bone mineral density and osteoporosis risk in a cohort of Dutch fracture patients

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072620

Molecular mechanism of ATP binding and ion channel activation in P2X receptors

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072620

P2X7 receptor-stimulation causes fever via PGE2 and IL-1β release

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072620

Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072620

Effects of genetic variation in the P2RX7 gene on pharmacodynamics of a P2X(7) receptor antagonist: a prospective genotyping approach

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072620

Single-nucleotide polymorphisms in the P2X7 receptor gene are associated with post-menopausal bone loss and vertebral fractures

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072620

Polymorphisms in the P2X7 receptor gene are associated with low lumbar spine bone mineral density and accelerated bone loss in post-menopausal women

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072620

Duloxetine, pregabalin, and duloxetine plus gabapentin for diabetic peripheral neuropathic pain management in patients with inadequate pain response to gabapentin: an open-label, randomized, noninferiority comparison.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072620

Residues 155 and 348 contribute to the determination of P2X7 receptor function via distinct mechanisms revealed by single-nucleotide polymorphisms

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072620

P2X7 receptor signaling pathway as a therapeutic target for neurodegenerative diseases

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072620

Single nucleotide polymorphisms that were identified in affective mood disorders affect ATP-activated P2X7 receptor functions

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072620

Identification and characterization of a novel variant of the human P2X(7) receptor resulting in gain of function

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072620

Sex, gender, and pain: a review of recent clinical and experimental findings

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072620

Genetics of the P2X7 receptor and human disease.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072620

[3H]A-804598 ([3H]2-cyano-1-[(1S)-1-phenylethyl]-3-quinolin-5-ylguanidine) is a novel, potent, and selective antagonist radioligand for P2X7 receptors

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072620

Liaisons dangereuses: P2X(7) and the inflammasome.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072620

Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATP-gated P2X7 receptor

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072620

A-740003 [N-(1-{[(cyanoimino)(5-quinolinylamino) methyl]amino}-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide], a novel and selective P2X7 receptor antagonist, dose-dependently reduces neuropathic pain in the rat

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072620

A His-155 to Tyr polymorphism confers gain-of-function to the human P2X7 receptor of human leukemic lymphocytes.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072620

Disruption of the P2X7 purinoceptor gene abolishes chronic inflammatory and neuropathic pain

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072620

Novel P2X7 receptor antagonists

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072620

Deletion of the P2X7 nucleotide receptor reveals its regulatory roles in bone formation and resorption

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072620

The melanocortin-1 receptor gene mediates female-specific mechanisms of analgesia in mice and humans

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072620

Molecular physiology of P2X receptors

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072620

Absence of the P2X7 receptor alters leukocyte function and attenuates an inflammatory response

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072620

Rapid secretion of interleukin-1beta by microvesicle shedding

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072620

A Glu-496 to Ala polymorphism leads to loss of function of the human P2X7 receptor

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072620

Altered cytokine production in mice lacking P2X(7) receptors

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072620

Ionic effects on human recombinant P2X7 receptor function

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072620

The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7)

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072620

P2X receptors bring new structure to ligand-gated ion channels

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072620

Antinociceptive effect of a new P(2Z)/P2X7 antagonist, oxidized ATP, in arthritic rats

4 July 2018

1 reference

https://api.crossref.org/works/10.1186%2F1744-8069-10-37

The neuroprotective effect of a specific P2X₇ receptor antagonist derives from its ability to inhibit assembly of the NLRP3 inflammasome in glial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1744-8069-10-37

P2X7 receptor channels allow direct permeation of nanometer-sized dyes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1744-8069-10-37

A comparative study of interleukin-1beta production and p2x7 expression after ATP stimulation by peripheral blood mononuclear cells isolated from rheumatoid arthritis patients and normal healthy controls.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1744-8069-10-37

Two haplotypes of the P2X(7) receptor containing the Ala-348 to Thr polymorphism exhibit a gain-of-function effect and enhanced interleukin-1beta secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1744-8069-10-37

The A118G single nucleotide polymorphism of the mu-opioid receptor gene (OPRM1) is associated with pressure pain sensitivity in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1744-8069-10-37

Effect of P2X(7) receptor knockout on exocrine secretion of pancreas, salivary glands and lacrimal glands

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1744-8069-10-37

Altered cytokine levels in the blood and cerebrospinal fluid of chronic pain patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1744-8069-10-37

Single nucleotide polymorphisms in the P2X7 gene are associated to fracture risk and to effect of estrogen treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1744-8069-10-37

A practical two-step quantitative clinical and electrophysiological assessment for the diagnosis and staging of diabetic neuropathy

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24934217

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Extracellular ATP triggers IL-1 beta release by activating the purinergic P2Z receptor of human macrophages

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24934217

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Crystallinity segregation upon selective self-assembling of gold colloidal single nanocrystals.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24934217

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1744-8069-10-37

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24934217%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

20 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24934217%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24934217%20AND%20SRC:MED&resulttype=core&format=json