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Hydroxychloroquine inhibits autophagy to potentiate antiestrogen responsiveness in ER+ breast cancer.
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PMCID
4073207
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24928945%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
title
Hydroxychloroquine inhibits autophagy to potentiate antiestrogen responsiveness in ER+ breast cancer
(English)
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PMCID
4073207
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24928945%20AND%20SRC:MED&resulttype=core&format=json
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20 March 2020
main subject
autophagy
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hydroxychloroquine
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author
Katherine Cook
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1
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Europe PubMed Central
PMCID
4073207
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24928945%20AND%20SRC:MED&resulttype=core&format=json
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20 March 2020
author name string
Anni Wärri
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2
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4073207
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24928945%20AND%20SRC:MED&resulttype=core&format=json
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20 March 2020
David R Soto-Pantoja
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3
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4073207
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24928945%20AND%20SRC:MED&resulttype=core&format=json
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20 March 2020
Pamela Ag Clarke
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4
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4073207
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20 March 2020
M Idalia Cruz
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5
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4073207
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24928945%20AND%20SRC:MED&resulttype=core&format=json
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20 March 2020
Alan Zwart
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6
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PMCID
4073207
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24928945%20AND%20SRC:MED&resulttype=core&format=json
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20 March 2020
Robert Clarke
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7
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4073207
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20 March 2020
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1 June 2014
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4073207
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20 March 2020
published in
Clinical Cancer Research
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4073207
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24928945%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
volume
20
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4073207
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20 March 2020
issue
12
1 reference
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Europe PubMed Central
PMCID
4073207
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24928945%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
page(s)
3222-3232
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Europe PubMed Central
PMCID
4073207
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24928945%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
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11 June 2022
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https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4073207/fullTextXML
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GX15-070 (obatoclax) induces apoptosis and inhibits cathepsin D- and L-mediated autophagosomal lysis in antiestrogen-resistant breast cancer cells
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4 July 2018
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Glucose-regulated protein 78 controls cross-talk between apoptosis and autophagy to determine antiestrogen responsiveness
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4 July 2018
The G protein-coupled receptor GPR30 mediates the proliferative and invasive effects induced by hydroxytamoxifen in endometrial cancer cells
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4 July 2018
Endoplasmic reticulum stress, the unfolded protein response, autophagy, and the integrated regulation of breast cancer cell fate.
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4 July 2018
Chloroquine sensitizes breast cancer cells to chemotherapy independent of autophagy
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4 July 2018
Tumor-associated macrophages in breast cancer: distinct subsets, distinct functions
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sFRP-1 binds via its netrin-related motif to the N-module of thrombospondin-1 and blocks thrombospondin-1 stimulation of MDA-MB-231 breast carcinoma cell adhesion and migration.
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Addition of a histone deacetylase inhibitor redirects tamoxifen-treated breast cancer cells into apoptosis, which is opposed by the induction of autophagy
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4 July 2018
What is the malignant nature of human ductal carcinoma in situ?
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Experimental treatment of oestrogen receptor (ER) positive breast cancer with tamoxifen and brivanib alaninate, a VEGFR-2/FGFR-1 kinase inhibitor: a potential clinical application of angiogenesis inhibitors
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Chloroquine and its analogs: a new promise of an old drug for effective and safe cancer therapies
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Angiotensin-(1-7) inhibits tumor angiogenesis in human lung cancer xenografts with a reduction in vascular endothelial growth factor
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4 July 2018
Gene network signaling in hormone responsiveness modifies apoptosis and autophagy in breast cancer cells
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Autophagy facilitates the progression of ERalpha-positive breast cancer cells to antiestrogen resistance
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4 July 2018
A role for macroautophagy in protection against 4-hydroxytamoxifen-induced cell death and the development of antiestrogen resistance
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4 July 2018
Predicting prognosis using molecular profiling in estrogen receptor-positive breast cancer treated with tamoxifen
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4 July 2018
Ataxia telangiectasia-mutated and p53 are potential mediators of chloroquine-induced resistance to mammary carcinogenesis
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4 July 2018
Antiestrogens, aromatase inhibitors, and apoptosis in breast cancer
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4 July 2018
Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer
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4 July 2018
Estrogen as an immunomodulator
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4 July 2018
Small-sample inference for incomplete longitudinal data with truncation and censoring in tumor xenograft models
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4 July 2018
Molecular and pharmacological aspects of antiestrogen resistance
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4 July 2018
Cellular and molecular pharmacology of antiestrogen action and resistance
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4 July 2018
MCF7/LCC9: an antiestrogen-resistant MCF-7 variant in which acquired resistance to the steroidal antiestrogen ICI 182,780 confers an early cross-resistance to the nonsteroidal antiestrogen tamoxifen
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4 July 2018
Current pathologic methods for measuring intratumoral microvessel density within breast carcinoma and other solid tumors
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4 July 2018
Hormonal aspects of breast cancer. Growth factors, drugs and stromal interactions
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4 July 2018
Responses to retinoic acid of tamoxifen-sensitive and -resistant sublines of human breast cancer cell line MCF-7
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4 July 2018
Hydroxychloroquine for chronic myeloid leukemia: complete cure on the horizon?
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30 October 2018
The 76-gene signature defines high-risk patients that benefit from adjuvant tamoxifen therapy.
1 reference
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073207
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30 October 2018
Relation of in vitro properties to tumorigenicity for a series of sublines of the human breast cancer cell line MCF-7
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24928945
retrieved
12 December 2020
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Identifiers
DOI
10.1158/1078-0432.CCR-13-3227
1 reference
stated in
Europe PubMed Central
PMCID
4073207
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24928945%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
PMCID
4073207
1 reference
stated in
Europe PubMed Central
PMCID
4073207
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24928945%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
PubMed ID
24928945
1 reference
stated in
Europe PubMed Central
PMCID
4073207
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24928945%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
ResearchGate publication ID
264455362
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